SNAPIN and NME7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SNAPIN	NME7
Description		SNAP associated protein	NME/NM23 family member 7
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Vesicle Manchette Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Cytosol Synaptic Vesicle Membrane Secretory Granule Synaptic Vesicle Membrane BLOC-1 Complex Cytoplasmic Vesicle Synapse Perinuclear Region Of Cytoplasm Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm Microvesicle	Gamma-tubulin Ring Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Axonemal Microtubule Plasma Membrane Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	SNARE Binding Protein Binding	Nucleoside Diphosphate Kinase Activity Protein Kinase Activity Protein Binding ATP Binding 3'-5'-DNA Exonuclease Activity Kinase Activity Transferase Activity Hydrolase Activity
	Biological Process	Intracellular Protein Transport Exocytosis Lysosome Organization Lysosomal Lumen Acidification Chemical Synaptic Transmission Neurotransmitter Secretion Anterograde Axonal Transport Retrograde Axonal Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Protein-containing Complex Localization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Melanosome Organization Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Protein Maturation Establishment Of Vesicle Localization Regulation Of Lysosome Size Neuron Cellular Homeostasis Organelle Transport Along Microtubule Terminal Button Organization Autophagosome Maturation Late Endosome To Lysosome Transport Positive Regulation Of Late Endosome To Lysosome Transport Regulation Of Synaptic Vesicle Exocytosis	Epithelial Cilium Movement Involved In Extracellular Fluid Movement GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process DNA Catabolic Process Determination Of Left/right Symmetry Brain Development Regulation Of Microtubule Nucleation Flagellated Sperm Motility Intraciliary Transport Receptor Clustering Cilium Assembly Left/right Pattern Formation Cellular Response To Leukemia Inhibitory Factor
Pathways		Golgi Associated Vesicle Biogenesis	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) D-dimer levels ( 21502573) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left-handedness ( 32989287) Myocardial infarction ( 33532862) Pulse pressure ( 27841878 30578418) QT interval ( 30679814) Systolic blood pressure ( 27841878 30578418) Venous thromboembolism ( 21980494 22672568 30659681 33592630)
Interacting Genes		103 interacting genes: ABI2 ACTN2 ATG14 ATP1A1 BANP BFSP1 BFSP2 BIN1 BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL C20orf202 CCDC102B CDC42BPA CEP170 CMYA5 CSNK1D DDR1 DENND1C DES DNM2 DOCK9 DST DTNBP1 DYRK3 DYSF EBAG9 EEF1G ELP1 ENO3 EXOC7 FAM114A1 FSD2 GPRASP1 GRIK1 HAP1 HMGB2 IKBIP IMMT KANK2 KAT5 KAT7 KIF5C KPNB1 KRT10 KRT15 KRT16 KRT17 KRT19 KRT20 KRT24 KRT26 LAMA2 LAMC1 LMNB1 LRP12 MACF1 MAPK14 MET MORC3 MTNR1A MYH14 MYH3 MYH7 NECAB2 NEDD9 NME7 NUP62CL PCYT1A PLAC9 PLEC PRKACA RABEP1 RABGEF1 RETREG1 RGS7 RNF13 SHBG SKA1 SMAD2 SMG1 SNAP23 SNAP25 SPAG5 SPP1 SPTB SPTBN1 ST7 TFIP11 TOMM70 TPM1 TPM2 TPM3 TPM4 TRIM63 TRPV1 TSG101 WASHC3 YWHAE YWHAZ	74 interacting genes: AMOTL2 ARHGAP9 BTBD6 CARD10 CBY2 CCDC136 CCDC33 CCDC88B CCHCR1 CDC42EP2 CEP72 DDIT4L DDX1 DISC1 DNAI7 EFHC2 FKBP6 FLOT1 FOSL1 FOSL2 GATAD2B GLIS2 GOLGA2 GSC2 HAUS8 IKZF1 IKZF3 INCA1 ISY1-RAB43 KRT18 KRT75 LNX1 MAP4K4 MED11 MED30 MEI4 MEOX2 MYOT NAB2 NEFL NFKBIL1 NIF3L1 NME4 NT5C2 OFD1 PAX4 PIAS2 PICK1 POU6F2 PROSER3 PSMA1 REL RUBCN SHTN1 SNAPIN SNX32 SYCE1 TCF4 TCHP TEKT1 TEPSIN THAP10 TNIP1 TNNI2 TRIM27 TRIM48 TUFT1 YWHAQ ZBTB48 ZNF23 ZNF263 ZNF343 ZNF526 ZNF620
Entrez ID		23557	29922
HPRD ID		06111	11394
Ensembl ID		ENSG00000143553	ENSG00000143156
Uniprot IDs		O95295	Q9Y5B8
PDB IDs			7UNG 8J07
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Cytoskeleton Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Organelle Organization Intermediate Filament Organization Establishment Of Organelle Localization Intermediate Filament Supramolecular Fiber Organization Organelle Localization Structural Constituent Of Cytoskeleton BLOC-1 Complex Actin Filament Binding Synaptic Vesicle Transport Establishment Of Vesicle Localization Structural Molecule Activity Axo-dendritic Transport Axon Cytoplasm Axonal Transport Vesicle Localization Establishment Of Localization In Cell Anterograde Axonal Transport Cytosol Anterograde Synaptic Vesicle Transport Muscle Thin Filament Tropomyosin Structural Constituent Of Skin Epidermis Cytoplasm Transport Along Microtubule Vesicle Transport Along Microtubule Cellular Localization Cytoskeleton-dependent Intracellular Transport Vesicle Cytoskeletal Trafficking Regulation Of Cellular Component Organization Microtubule-based Transport Melanosome Organization Keratin Filament Intracellular Transport Pigment Granule Organization Structural Constituent Of Muscle Actomyosin Structure Organization Muscle System Process Actin Binding Muscle Contraction Extracellular Exosome Contractile Muscle Fiber Stress Fiber Organelle Transport Along Microtubule Tissue Morphogenesis Intracellular Protein Localization Z Disc	Protein Binding Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Transcription Coregulator Activity Regulation Of RNA Metabolic Process Phosphatidylinositol 3-kinase Inhibitor Activity
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