NME7 and DDIT4L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NME7	DDIT4L
Description		NME/NM23 family member 7	DNA damage inducible transcript 4 like
Image			No pdb structure
GO Annotations	Cellular Component	Gamma-tubulin Ring Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Axonemal Microtubule Plasma Membrane Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Cytoplasm
	Molecular Function	Nucleoside Diphosphate Kinase Activity Protein Kinase Activity Protein Binding ATP Binding 3'-5'-DNA Exonuclease Activity Kinase Activity Transferase Activity Hydrolase Activity	Protein Binding
	Biological Process	Epithelial Cilium Movement Involved In Extracellular Fluid Movement GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process DNA Catabolic Process Determination Of Left/right Symmetry Brain Development Regulation Of Microtubule Nucleation Flagellated Sperm Motility Intraciliary Transport Receptor Clustering Cilium Assembly Left/right Pattern Formation Cellular Response To Leukemia Inhibitory Factor	Negative Regulation Of Signal Transduction
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) D-dimer levels ( 21502573) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left-handedness ( 32989287) Myocardial infarction ( 33532862) Pulse pressure ( 27841878 30578418) QT interval ( 30679814) Systolic blood pressure ( 27841878 30578418) Venous thromboembolism ( 21980494 22672568 30659681 33592630)	Alcohol consumption (drinks per week) ( 30643258) Nose size ( 27182965)
Interacting Genes		74 interacting genes: AMOTL2 ARHGAP9 BTBD6 CARD10 CBY2 CCDC136 CCDC33 CCDC88B CCHCR1 CDC42EP2 CEP72 DDIT4L DDX1 DISC1 DNAI7 EFHC2 FKBP6 FLOT1 FOSL1 FOSL2 GATAD2B GLIS2 GOLGA2 GSC2 HAUS8 IKZF1 IKZF3 INCA1 ISY1-RAB43 KRT18 KRT75 LNX1 MAP4K4 MED11 MED30 MEI4 MEOX2 MYOT NAB2 NEFL NFKBIL1 NIF3L1 NME4 NT5C2 OFD1 PAX4 PIAS2 PICK1 POU6F2 PROSER3 PSMA1 REL RUBCN SHTN1 SNAPIN SNX32 SYCE1 TCF4 TCHP TEKT1 TEPSIN THAP10 TNIP1 TNNI2 TRIM27 TRIM48 TUFT1 YWHAQ ZBTB48 ZNF23 ZNF263 ZNF343 ZNF526 ZNF620	155 interacting genes: ABCB11 ACY3 AFMID AIDA AKT1 ARK2N ARPIN BAG4 BANF2 BCL2L14 BID C14orf119 C19orf25 C5orf22 CABP5 CALCOCO2 CALM1 CALM2 CALM3 CATIP CCNK CDA CDKN2D CDPF1 CHMP1A CLIC3 CLK2 CLK3 CPNE7 CRLF3 CRYBB1 DBI DNPH1 DUSP23 DUSP29 EIF4A3 EIF4EBP1 EIF4H EPHB6 EXOSC1 EXOSC5 EXOSC8 FAAP20 FADD FAM200C FHIT FHL2 FKBP6 FLNA GADD45G GEMIN6 GPKOW GRB2 GUCA1A HDAC7 HMG20A HSPB7 IL36RN IMPDH1 KANK2 KCTD9 KDM8 KRT34 KRTAP5-6 LENG1 LGALS14 LGALSL LMO1 LRATD2 LSM3 LSM5 LSM7 MAP3K7CL MAPRE2 MAPRE3 MEMO1 MIEN1 MKRN3 MLX MORF4L2 MT1M MYG1 MYLIP NAA10 NAV1 NEK6 NGB NHLRC4 NME7 NQO2 NR2C2AP NUDT2 NUDT22 NXT2 PARVG PCBP3 PDE4C PFKFB1 PLSCR4 PM20D2 PMVK PPCDC PPIL1 PPP1R27 PRKAB2 PRPF40A PSMA1 PSMB9 PTS PUF60 RAB32 RFC5 RFPL3 RPIA RPL22 RPRD1B SCOC SEC22A SEPTIN1 SEPTIN3 SEPTIN5 SH3BGRL3 SNRPA SNRPG SREK1IP1 STK16 STK4 SULT2B1 TBC1D22B TCL1A TCP11L1 TEKT4 TEX14 TFPT TNS2 TOLLIP TRIM73 TSEN15 TSSK3 TTC5 TXN TXNL4A TYW3 UBASH3A UBTFL1 VBP1 VCX2 VPS26C YES1 YOD1 YPEL5 ZNF593 ZNF76 ZNF765 ZSCAN23
Entrez ID		29922	115265
HPRD ID		11394	09663
Ensembl ID		ENSG00000143156	ENSG00000145358
Uniprot IDs		Q9Y5B8	Q96D03
PDB IDs		7UNG 8J07
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Transcription Coregulator Activity Regulation Of RNA Metabolic Process Phosphatidylinositol 3-kinase Inhibitor Activity	Protein Binding Cytoplasm Nucleus MRNA Splicing, Via Spliceosome MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Identical Protein Binding Cytosol U4/U6 X U5 Tri-snRNP Complex MRNA Processing RNA Splicing Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Lsm1-7-Pat1 Complex RNA Processing Nucleobase-containing Compound Metabolic Process Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Lsm2-8 Complex Protein Serine/threonine Kinase Activator Activity Spliceosomal Complex U6 SnRNP Protein Kinase Binding Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Nucleolar Exosome (RNase Complex) U2-type Precatalytic Spliceosome Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Nucleoplasm Titin Binding Septin Ring Septin Complex Cell Division Site Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Detection Of Calcium Ion Nucleobase-containing Compound Catabolic Process Regulation Of Cell Communication By Electrical Coupling Nuclear Exosome (RNase Complex) U2-type Prespliceosome Exosome (RNase Complex) Phosphate-containing Compound Metabolic Process Protein Phosphatase Activator Activity Microtubule Cytoskeleton Calyx Of Held U1 SnRNP RNA Metabolic Process Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Channel Regulator Activity
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