SNAPIN and TRPV1

Number of citations of the paper that reports this interaction (PMID 15066994)
52

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)

		SNAPIN	TRPV1
Gene Name		SNAP-associated protein	transient receptor potential cation channel, subfamily V, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleolus Golgi Apparatus Synaptic Vesicle Cell Junction Transport Vesicle Secretory Granule Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane BLOC-1 Complex Synapse Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Cell Junction Intrinsic Component Of Plasma Membrane Dendritic Spine Membrane Postsynaptic Membrane
	Molecular Function	SNARE Binding Protein Binding	Transmembrane Signaling Receptor Activity Excitatory Extracellular Ligand-gated Ion Channel Activity Calcium Channel Activity Calmodulin Binding ATP Binding Calcium-release Channel Activity Phosphoprotein Binding
	Biological Process	Intracellular Protein Transport Neurotransmitter Secretion Anterograde Axon Cargo Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Viral Process Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Membrane Melanosome Organization Regulation Of Protein Binding Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Terminal Button Organization Autophagic Vacuole Maturation Positive Regulation Of Late Endosome To Lysosome Transport	Transport Cell Surface Receptor Signaling Pathway Chemosensory Behavior Ion Transmembrane Transport Thermoception Transmembrane Transport Calcium Ion Transmembrane Transport Cellular Response To Alkaloid Cellular Response To ATP
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Ion channel transport TRP channels Stimuli-sensing channels
Drugs			Alpha-Linolenic Acid Icosapent Aspartame
Diseases
GWAS
Protein-Protein Interactions		33 interactors: BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL CSNK1D DDR1 DTNBP1 EBAG9 EEF1G GPRASP1 HAP1 IKBKAP IMMT KAT5 KAT7 KIF5C LAMC1 LRP12 MAPK14 MET PRKACA RGS7 RNF13 SHBG SMAD2 SNAP23 SNAP25 SPAG5 SPP1 ST7 TRPV1	7 interactors: CALM1 EGFR ITCH PRKCE SNAPIN SYT9 TRPV2
Entrez ID		23557	7442
HPRD ID		06111	03648
Ensembl ID		ENSG00000143553	ENSG00000196689
Uniprot IDs		O95295	E7EQ78 Q8NER1
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Axon Cargo Transport Synaptic Vesicle Transport Establishment Of Vesicle Localization Vesicle Localization Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Vesicle Organization Establishment Of Organelle Localization Microtubule-based Transport Cell-cell Signaling Movement Of Cell Or Subcellular Component Organelle Localization Synaptic Transmission Microtubule-based Movement Pigmentation Microtubule-based Process Post-Golgi Vesicle-mediated Transport Organelle Organization Vesicle-mediated Transport Platelet Dense Granule Organization Generation Of Neurons Signaling Neurogenesis Neuron Projection Development Cell Communication Cell Projection Organization Cell Development Cell Differentiation Neuron Development Nervous System Development Response To Stimulus Establishment Of Localization In Cell Regulation Of Growth Neuron Differentiation Membrane Organization Transport Secretory Granule Organization Intracellular Transport Peptidyl-amino Acid Modification Golgi Vesicle Transport System Development Cellular Localization Cellular Process Endosome To Melanosome Transport Pigment Granule Maturation Synaptic Vesicle Docking	Positive Regulation Of Transport Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Cellular Localization Immune Response-regulating Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Innate Immune Response Regulation Of Nitric-oxide Synthase Activity Fc Receptor Signaling Pathway Regulation Of Immune Response Negative Regulation Of Transporter Activity Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Regulation Of Cytokinesis Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Abiotic Stimulus Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Ion Transmembrane Transport Regulation Of Intracellular Transport Regulation Of Oxidoreductase Activity Positive Regulation Of Ion Transmembrane Transport Immune Response Regulation Of Immune System Process Regulation Of Phosphorylation Regulation Of Cellular Ketone Metabolic Process Alkanesulfonate Metabolic Process Positive Regulation Of Late Endosome To Lysosome Transport Positive Regulation Of Cellular Glucuronidation Defense Response Positive Regulation Of Calcium Ion Transport Calcium-mediated Signaling Negative Regulation Of Ion Transport Positive Regulation Of Synaptic Transmission Regulation Of Phosphorus Metabolic Process Reactive Oxygen Species Metabolic Process Cellular Response To Growth Factor Stimulus Response To Calcium Ion Response To Growth Factor Regulation Of MAPK Cascade TRAM-dependent Toll-like Receptor 4 Signaling Pathway Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling
Tagcloud ?		acidic adaptor altogether bace1 brains cleaving coupling defective deleting disrupting dynein endocytic endosomes enhancing generating happ live lysosomal lysosomes mechanistic organelles overexpressing reduces rescue retrograde secretase traffic transport turnover	6h ag anandamide arachidonoylglycerol ascaris beagle cannabinoid capsaicin cb1 cb2 congener dependently desensitization desensitized dogs endocannabinoid hek hypersensitive ic50 keratinocytes micronized mum palmitoylethanolamide pea spontaneously suum ultramicronized vanilloid volunteers
Tagcloud (Difference) ?		acidic adaptor altogether bace1 brains cleaving coupling defective deleting disrupting dynein endocytic endosomes enhancing generating happ live lysosomal lysosomes mechanistic organelles overexpressing reduces rescue retrograde secretase traffic transport turnover	6h ag anandamide arachidonoylglycerol ascaris beagle cannabinoid capsaicin cb1 cb2 congener dependently desensitization desensitized dogs endocannabinoid hek hypersensitive ic50 keratinocytes micronized mum palmitoylethanolamide pea spontaneously suum ultramicronized vanilloid volunteers
Tagcloud (Intersection) ?