SNAPIN and RGS7

Number of citations of the paper that reports this interaction (PMID 12659861)
7

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SNAPIN	RGS7
Gene Name		SNAP-associated protein	regulator of G-protein signaling 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleolus Golgi Apparatus Synaptic Vesicle Cell Junction Transport Vesicle Secretory Granule Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane BLOC-1 Complex Synapse Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Cytosol Heterotrimeric G-protein Complex Plasma Membrane Dendrite Terminus
	Molecular Function	SNARE Binding Protein Binding	Signal Transducer Activity GTPase Activator Activity G-protein Beta-subunit Binding
	Biological Process	Intracellular Protein Transport Neurotransmitter Secretion Anterograde Axon Cargo Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Viral Process Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Membrane Melanosome Organization Regulation Of Protein Binding Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Terminal Button Organization Autophagic Vacuole Maturation Positive Regulation Of Late Endosome To Lysosome Transport	G-protein Coupled Receptor Signaling Pathway Intracellular Signal Transduction Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Signaling by GPCR GPCR downstream signaling G alpha (i) signalling events
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		33 interactors: BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL CSNK1D DDR1 DTNBP1 EBAG9 EEF1G GPRASP1 HAP1 IKBKAP IMMT KAT5 KAT7 KIF5C LAMC1 LRP12 MAPK14 MET PRKACA RGS7 RNF13 SHBG SMAD2 SNAP23 SNAP25 SPAG5 SPP1 ST7 TRPV1	12 interactors: GNAI1 GNAI3 GNAO1 GNAQ GNAZ GNB5 MSX1 PKD1 PRKCA SNAPIN YWHAB YWHAQ
Entrez ID		23557	6000
HPRD ID		06111	03948
Ensembl ID		ENSG00000143553	ENSG00000182901
Uniprot IDs		O95295	P49802
PDB IDs			2A72 2D9J
Enriched GO Terms of Interacting Partners?		Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Axon Cargo Transport Synaptic Vesicle Transport Establishment Of Vesicle Localization Vesicle Localization Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Vesicle Organization Establishment Of Organelle Localization Microtubule-based Transport Cell-cell Signaling Movement Of Cell Or Subcellular Component Organelle Localization Synaptic Transmission Microtubule-based Movement Pigmentation Microtubule-based Process Post-Golgi Vesicle-mediated Transport Organelle Organization Vesicle-mediated Transport Platelet Dense Granule Organization Generation Of Neurons Signaling Neurogenesis Neuron Projection Development Cell Communication Cell Projection Organization Cell Development Cell Differentiation Neuron Development Nervous System Development Response To Stimulus Establishment Of Localization In Cell Regulation Of Growth Neuron Differentiation Membrane Organization Transport Secretory Granule Organization Intracellular Transport Peptidyl-amino Acid Modification Golgi Vesicle Transport System Development Cellular Localization Cellular Process Endosome To Melanosome Transport Pigment Granule Maturation Synaptic Vesicle Docking	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Signaling Cell Communication Cell Surface Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Signal Transduction Negative Regulation Of Transport Regulation Of Intracellular Transport Membrane Organization Platelet Activation Vesicle Fusion Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of Cellular Localization Organelle Fusion Cellular Response To Stimulus Regulation Of Establishment Of Protein Localization Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Protein Localization Membrane Fusion Positive Regulation Of Organelle Organization Nervous System Development Positive Regulation Of Blood Vessel Endothelial Cell Migration Blood Coagulation Hemostasis Negative Regulation Of Adenylate Cyclase Activity Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Lyase Activity Response To Stimulus Cytoplasmic Sequestering Of Protein Central Nervous System Development Regulation Of Rhodopsin Mediated Signaling Pathway Detection Of Abiotic Stimulus Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of CAMP Biosynthetic Process Intrinsic Apoptotic Signaling Pathway Rhodopsin Mediated Signaling Pathway Negative Regulation Of CAMP Metabolic Process Cartilage Development Positive Regulation Of Apoptotic Signaling Pathway Skeletal System Development Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Dopamine Receptor Signaling Pathway Vesicle Organization Regulation Of Body Fluid Levels Synaptic Transmission Wound Healing Negative Regulation Of Nucleotide Metabolic Process Negative Regulation Of Calcium Ion Transport Regulation Of Protein Transport
Tagcloud ?		acidic adaptor altogether bace1 brains cleaving coupling defective deleting disrupting dynein endocytic endosomes enhancing generating happ live lysosomal lysosomes mechanistic organelles overexpressing reduces rescue retrograde secretase traffic transport turnover	2a ag490 attenuated cortex corticosterone dependently desensitization frontal hormone hypothalamic increases jak mediating necessary nucleus olanzapine oxytocin paraventricular phospholipase prevented rat reductions regulator release reverse serotonin stat stimulated understand
Tagcloud (Difference) ?		acidic adaptor altogether bace1 brains cleaving coupling defective deleting disrupting dynein endocytic endosomes enhancing generating happ live lysosomal lysosomes mechanistic organelles overexpressing reduces rescue retrograde secretase traffic transport turnover	2a ag490 attenuated cortex corticosterone dependently desensitization frontal hormone hypothalamic increases jak mediating necessary nucleus olanzapine oxytocin paraventricular phospholipase prevented rat reductions regulator release reverse serotonin stat stimulated understand
Tagcloud (Intersection) ?