SNAPIN and KIF5C

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SNAPIN	KIF5C
Gene Name		SNAP-associated protein	kinesin family member 5C
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleolus Golgi Apparatus Synaptic Vesicle Cell Junction Transport Vesicle Secretory Granule Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane BLOC-1 Complex Synapse Perinuclear Region Of Cytoplasm	Cytoplasm Kinesin Complex Microtubule
	Molecular Function	SNARE Binding Protein Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity
	Biological Process	Intracellular Protein Transport Neurotransmitter Secretion Anterograde Axon Cargo Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Viral Process Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Membrane Melanosome Organization Regulation Of Protein Binding Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Terminal Button Organization Autophagic Vacuole Maturation Positive Regulation Of Late Endosome To Lysosome Transport	Organelle Organization Microtubule-based Movement Axon Guidance Protein Localization Metabolic Process Cytoskeleton-dependent Intracellular Transport MRNA Transport
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Peptide hormone metabolism Insulin processing
Drugs
Diseases
GWAS			Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
Protein-Protein Interactions		33 interactors: BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL CSNK1D DDR1 DTNBP1 EBAG9 EEF1G GPRASP1 HAP1 IKBKAP IMMT KAT5 KAT7 KIF5C LAMC1 LRP12 MAPK14 MET PRKACA RGS7 RNF13 SHBG SMAD2 SNAP23 SNAP25 SPAG5 SPP1 ST7 TRPV1	7 interactors: CSNK2A1 KIF5A KLC1 KLC3 NCOA2 SNAPIN YWHAG
Entrez ID		23557	3800
HPRD ID		06111	18371
Ensembl ID		ENSG00000143553	ENSG00000168280
Uniprot IDs		O95295	O60282 Q59GB8
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Axon Cargo Transport Synaptic Vesicle Transport Establishment Of Vesicle Localization Vesicle Localization Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Vesicle Organization Establishment Of Organelle Localization Microtubule-based Transport Cell-cell Signaling Movement Of Cell Or Subcellular Component Organelle Localization Synaptic Transmission Microtubule-based Movement Pigmentation Microtubule-based Process Post-Golgi Vesicle-mediated Transport Organelle Organization Vesicle-mediated Transport Platelet Dense Granule Organization Generation Of Neurons Signaling Neurogenesis Neuron Projection Development Cell Communication Cell Projection Organization Cell Development Cell Differentiation Neuron Development Nervous System Development Response To Stimulus Establishment Of Localization In Cell Regulation Of Growth Neuron Differentiation Membrane Organization Transport Secretory Granule Organization Intracellular Transport Peptidyl-amino Acid Modification Golgi Vesicle Transport System Development Cellular Localization Cellular Process Endosome To Melanosome Transport Pigment Granule Maturation Synaptic Vesicle Docking	Cytoskeleton-dependent Intracellular Transport Axon Cargo Transport Microtubule-based Movement Microtubule-based Transport Movement Of Cell Or Subcellular Component Intracellular Transport Microtubule-based Process Establishment Of Localization In Cell Cellular Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Late Endosome To Lysosome Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Generation Of Neurons Stress Granule Disassembly Neurogenesis Terminal Button Organization Autophagic Vacuole Maturation Protein Localization Neuron Projection Development Intracellular Protein Transport Antigen Processing And Presentation Of Peptide Antigen Neuron Development Positive Regulation Of Intracellular Transport Nervous System Development Antigen Processing And Presentation Synaptic Vesicle Fusion To Presynaptic Membrane Neuron Differentiation Rhythmic Process Cell Projection Organization Synaptic Vesicle Maturation Axon Guidance Cellular Protein Localization Protein Localization To Synapse Transport Protein Transport Anterograde Synaptic Vesicle Transport Blood Coagulation Hemostasis Melanosome Organization Regulation Of Intracellular Transport Pigment Granule Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Establishment Of Protein Localization Organelle Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Anterograde Axon Cargo Transport Endosome To Lysosome Transport Axonogenesis Signaling
Tagcloud ?		acidic adaptor altogether bace1 brains cleaving coupling defective deleting disrupting dynein endocytic endosomes enhancing generating happ live lysosomal lysosomes mechanistic organelles overexpressing reduces rescue retrograde secretase traffic transport turnover	200x customized dcx depths dync1h1 exome flna funded heterotopia kinesin malformations megalencephaly mosaicism neurodevelopmental neuropsychiatric nodular pachygyria panels periventricular persons polymicrogyria read sanger somatic subcloned subcloning subcortical tubb2b unequal
Tagcloud (Difference) ?		acidic adaptor altogether bace1 brains cleaving coupling defective deleting disrupting dynein endocytic endosomes enhancing generating happ live lysosomal lysosomes mechanistic organelles overexpressing reduces rescue retrograde secretase traffic transport turnover	200x customized dcx depths dync1h1 exome flna funded heterotopia kinesin malformations megalencephaly mosaicism neurodevelopmental neuropsychiatric nodular pachygyria panels periventricular persons polymicrogyria read sanger somatic subcloned subcloning subcortical tubb2b unequal
Tagcloud (Intersection) ?