NME7 and TCHP

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		NME7	TCHP
Gene Name		NME/NM23 family member 7	trichoplein, keratin filament binding
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Ciliary Basal Body	Cytoplasm Mitochondrion Centrosome Plasma Membrane Keratin Filament Apical Cortex
	Molecular Function	Nucleoside Diphosphate Kinase Activity ATP Binding Metal Ion Binding	Protein Binding
	Biological Process	Epithelial Cilium Movement Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Determination Of Left/right Symmetry Brain Development Intraciliary Transport Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Left/right Pattern Formation	Apoptotic Process Negative Regulation Of Cell Growth
Pathways
Drugs
Diseases
GWAS		D-dimer levels ( 21502573) Venous thromboembolism ( 21980494 22672568)	Metabolite levels (MHPG) ( 23319000)
Protein-Protein Interactions		27 interactors: C1orf189 CCHCR1 CDC42EP2 CEP72 DDX1 FKBP6 FOSL1 GOLGA2 KIAA1598 KRT18 LNX1 MAP4K4 MYOT NAB2 NEFL NT5C2 OFD1 REL SYCE1 TCF4 TCHP TNIP1 TRIM27 TUFT1 YWHAQ ZBTB48 ZNF263	21 interactors: CCDC172 CCDC85B CDR2 DYDC1 KRT14 KRT15 KRT16 KRT18 KRT40 KRT5 KRT6A KRT8 LZTS2 MIPOL1 MKRN3 NAB2 NDOR1 NME7 TEX11 TRIM27 VIM
Entrez ID		29922	84260
HPRD ID		11394	14403
Ensembl ID		ENSG00000143156	ENSG00000139437
Uniprot IDs		Q9Y5B8	Q9BT92
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Gene Expression Cell Cycle Response To Corticosterone Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Response To Mineralocorticoid Negative Regulation Of Transcription, DNA-templated Intermediate Filament Cytoskeleton Organization Negative Regulation Of Nucleic Acid-templated Transcription Organelle Organization Negative Regulation Of RNA Biosynthetic Process Cytoskeleton Organization Intermediate Filament-based Process Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Golgi To Plasma Membrane CFTR Protein Transport Bone Mineralization Body Morphogenesis Developmental Process Transcription, DNA-templated Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Negative Regulation Of Interleukin-2 Secretion Gamma-tubulin Complex Localization Catenin Import Into Nucleus Vitellogenesis Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Cellular Component Assembly Negative Regulation Of Viral Process Biomineral Tissue Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Neurofilament Bundle Assembly Ossification Regulation Of Cellular Component Organization Maintenance Of DNA Repeat Elements RNA Metabolic Process Intracellular Transport Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Death Regulation Of Cellular Component Size Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Secretion	Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Developmental Process Cytoskeleton Organization Anatomical Structure Development Epidermis Development Hemidesmosome Assembly Epithelium Development Organelle Organization Hepatocyte Apoptotic Process Intermediate Filament Organization Cellular Component Assembly Tumor Necrosis Factor-mediated Signaling Pathway Response To Zinc Ion Cell-substrate Junction Assembly Tissue Development Golgi To Plasma Membrane CFTR Protein Transport Cellular Response To Menadione Negative Regulation Of Interleukin-2 Secretion Organ Development Cellular Response To Tumor Necrosis Factor Extrinsic Apoptotic Signaling Pathway Hair Cycle Meiotic Gene Conversion Response To Tumor Necrosis Factor Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Response To Inorganic Substance Negative Regulation Of Calcium Ion Import Male Meiosis Chromosome Segregation Intermediate Filament Bundle Assembly Cell Differentiation Response To Ionizing Radiation Cell Death Death Keratinocyte Migration Negative Regulation Of Transcription From RNA Polymerase III Promoter Epithelial Cell Differentiation Response To Hydrostatic Pressure Bergmann Glial Cell Differentiation Viral Process Interferon-gamma Secretion Chiasma Assembly
Tagcloud ?		acentrosomal associates cdk5rap2 centrosomal centrosomin contains fam128a gamma gcp2 impairs melanogaster microcephaly microtubule microtubules mto1p nucleating nucleation pcp1p pombe referred regrowth schizosaccharomyces stimulates tethering tubulin tuc tuna turc unaffected
Tagcloud (Difference) ?		acentrosomal associates cdk5rap2 centrosomal centrosomin contains fam128a gamma gcp2 impairs melanogaster microcephaly microtubule microtubules mto1p nucleating nucleation pcp1p pombe referred regrowth schizosaccharomyces stimulates tethering tubulin tuc tuna turc unaffected
Tagcloud (Intersection) ?