NME7 and CDC42EP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NME7	CDC42EP2
Gene Name		NME/NM23 family member 7	CDC42 effector protein (Rho GTPase binding) 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Ciliary Basal Body	Cytoplasm Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane
	Molecular Function	Nucleoside Diphosphate Kinase Activity ATP Binding Metal Ion Binding	Opioid Peptide Activity Rho GTPase Activator Activity Protein Binding GTP-Rho Binding
	Biological Process	Epithelial Cilium Movement Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Determination Of Left/right Symmetry Brain Development Intraciliary Transport Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Left/right Pattern Formation	Actin Filament Organization Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein Complex Assembly Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS		D-dimer levels ( 21502573) Venous thromboembolism ( 21980494 22672568)
Protein-Protein Interactions		27 interactors: C1orf189 CCHCR1 CDC42EP2 CEP72 DDX1 FKBP6 FOSL1 GOLGA2 KIAA1598 KRT18 LNX1 MAP4K4 MYOT NAB2 NEFL NT5C2 OFD1 REL SYCE1 TCF4 TCHP TNIP1 TRIM27 TUFT1 YWHAQ ZBTB48 ZNF263	7 interactors: ARHGAP26 CDC42 NME7 RHOQ SEPT6 SEPT7 SNCA
Entrez ID		29922	10435
HPRD ID		11394	09363
Ensembl ID		ENSG00000143156	ENSG00000149798
Uniprot IDs		Q9Y5B8	O14613
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Gene Expression Cell Cycle Response To Corticosterone Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Response To Mineralocorticoid Negative Regulation Of Transcription, DNA-templated Intermediate Filament Cytoskeleton Organization Negative Regulation Of Nucleic Acid-templated Transcription Organelle Organization Negative Regulation Of RNA Biosynthetic Process Cytoskeleton Organization Intermediate Filament-based Process Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Golgi To Plasma Membrane CFTR Protein Transport Bone Mineralization Body Morphogenesis Developmental Process Transcription, DNA-templated Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Negative Regulation Of Interleukin-2 Secretion Gamma-tubulin Complex Localization Catenin Import Into Nucleus Vitellogenesis Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Cellular Component Assembly Negative Regulation Of Viral Process Biomineral Tissue Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Neurofilament Bundle Assembly Ossification Regulation Of Cellular Component Organization Maintenance Of DNA Repeat Elements RNA Metabolic Process Intracellular Transport Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Death Regulation Of Cellular Component Size Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Secretion	Organelle Organization Regulation Of Filopodium Assembly Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Morphogenesis Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Regulation Of Cytoskeleton Organization Regulation Of Peptidyl-serine Phosphorylation Cytokinesis Regulation Of Cell Projection Assembly Actin Cytoskeleton Organization Small GTPase Mediated Signal Transduction Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of Embryonic Cell Shape Positive Regulation Of Hair Follicle Cell Proliferation Actin Filament-based Process Microtubule-based Transport Negative Regulation Of Protein Complex Assembly Regulation Of Protein Stability Cytoskeleton-dependent Intracellular Transport Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Dopamine Metabolic Process Submandibular Salivary Gland Formation Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Actin Filament Branching Negative Regulation Of Cellular Respiration Positive Regulation Of Transport Regulation Of Cell Shape Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Microtubule-based Process Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Regulation Of Cellular Component Organization Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Membrane Organization Establishment Of Golgi Localization Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Organelle Organization Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Intracellular Transport Regulation Of Neuron Apoptotic Process Purine Nucleoside Metabolic Process Regulation Of Synaptic Vesicle Recycling
Tagcloud ?		acentrosomal associates cdk5rap2 centrosomal centrosomin contains fam128a gamma gcp2 impairs melanogaster microcephaly microtubule microtubules mto1p nucleating nucleation pcp1p pombe referred regrowth schizosaccharomyces stimulates tethering tubulin tuc tuna turc unaffected
Tagcloud (Difference) ?		acentrosomal associates cdk5rap2 centrosomal centrosomin contains fam128a gamma gcp2 impairs melanogaster microcephaly microtubule microtubules mto1p nucleating nucleation pcp1p pombe referred regrowth schizosaccharomyces stimulates tethering tubulin tuc tuna turc unaffected
Tagcloud (Intersection) ?