SNAPIN and HAP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SNAPIN	HAP1
Description		SNAP associated protein	huntingtin associated protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Vesicle Manchette Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Cytosol Synaptic Vesicle Membrane Secretory Granule Synaptic Vesicle Membrane BLOC-1 Complex Cytoplasmic Vesicle Synapse Perinuclear Region Of Cytoplasm Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm Microvesicle	Nucleus Nucleolus Cytoplasm Mitochondrion Lysosome Endosome Early Endosome Autophagosome Endoplasmic Reticulum Centrosome Centriole Cytosol Cytoskeleton Synaptic Vesicle Actin Cytoskeleton Inclusion Body Axon Dendrite Growth Cone Cytoplasmic Vesicle Cell Projection Neuron Projection Dendritic Spine Synapse Presynapse Axon Cytoplasm
	Molecular Function	SNARE Binding Protein Binding	Signaling Receptor Binding Protein Binding Myosin Binding Transmembrane Transporter Binding Brain-derived Neurotrophic Factor Binding
	Biological Process	Intracellular Protein Transport Exocytosis Lysosome Organization Lysosomal Lumen Acidification Chemical Synaptic Transmission Neurotransmitter Secretion Anterograde Axonal Transport Retrograde Axonal Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Protein-containing Complex Localization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Melanosome Organization Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Protein Maturation Establishment Of Vesicle Localization Regulation Of Lysosome Size Neuron Cellular Homeostasis Organelle Transport Along Microtubule Terminal Button Organization Autophagosome Maturation Late Endosome To Lysosome Transport Positive Regulation Of Late Endosome To Lysosome Transport Regulation Of Synaptic Vesicle Exocytosis	Protein Targeting Exocytosis Autophagy Chemical Synaptic Transmission Brain Development Anterograde Axonal Transport Retrograde Axonal Transport Intracellular Protein Localization Protein Transport Regulation Of Exocytosis Cerebellum Development Hypothalamus Cell Differentiation Neurogenesis Cell Projection Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Neurotrophin Production Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vesicle Transport Along Microtubule Neurotrophin TRK Receptor Signaling Pathway Mitochondrion Distribution Positive Regulation Of Neurogenesis Negative Regulation Of Amyloid-beta Formation Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Non-motile Cilium Assembly
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Developmental language disorder (syntactic complexity) ( 27016271) Esophageal cancer (squamous cell) ( 22960999)
Interacting Genes		103 interacting genes: ABI2 ACTN2 ATG14 ATP1A1 BANP BFSP1 BFSP2 BIN1 BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL C20orf202 CCDC102B CDC42BPA CEP170 CMYA5 CSNK1D DDR1 DENND1C DES DNM2 DOCK9 DST DTNBP1 DYRK3 DYSF EBAG9 EEF1G ELP1 ENO3 EXOC7 FAM114A1 FSD2 GPRASP1 GRIK1 HAP1 HMGB2 IKBIP IMMT KANK2 KAT5 KAT7 KIF5C KPNB1 KRT10 KRT15 KRT16 KRT17 KRT19 KRT20 KRT24 KRT26 LAMA2 LAMC1 LMNB1 LRP12 MACF1 MAPK14 MET MORC3 MTNR1A MYH14 MYH3 MYH7 NECAB2 NEDD9 NME7 NUP62CL PCYT1A PLAC9 PLEC PRKACA RABEP1 RABGEF1 RETREG1 RGS7 RNF13 SHBG SKA1 SMAD2 SMG1 SNAP23 SNAP25 SPAG5 SPP1 SPTB SPTBN1 ST7 TFIP11 TOMM70 TPM1 TPM2 TPM3 TPM4 TRIM63 TRPV1 TSG101 WASHC3 YWHAE YWHAZ	93 interacting genes: AEN ANTKMT APLP1 ATP5MF BARD1 BRD7 C1orf216 C7orf25 C8orf33 CATSPERT CBX8 CCDC13 CDC73 CDK18 CDK5RAP2 CFAP263 COL9A2 CRIP1 DCTN1 DDX49 DEFB1 EIF3E FAM50B FEZ1 GABARAPL2 GADD45G GIT1 GPRASP2 HDAC4 HGS HMOX2 HOXB5 HSPA1A HSPA4 HTT IMMT ING5 KAT5 KAT7 KATNBL1 KBTBD7 KPNA2 LRIF1 LUC7L2 MPP3 MRPS9 MSGN1 NAP1L5 NDUFB9 NEUROD1 NIPSNAP3A NOD2 NOP53 PABPC4 PCM1 PDCD7 PFDN1 PKN1 PPID PPOX PPP1R18 PRPF31 PSMD11 RER1 RHPN1 RIF1 RPS10 RPS25 SCNM1 SNAPIN SRSF4 STX5 TAF1D TBP TIMM17A TNNT1 TNNT3 TOMM20 TSPYL1 UTP3 VIM ZFP1 ZMAT2 ZNF124 ZNF20 ZNF24 ZNF33B ZNF490 ZNF572 ZNF575 ZNF648 ZNF691 ZNF835
Entrez ID		23557	9001
HPRD ID		06111	02972
Ensembl ID		ENSG00000143553	ENSG00000173805
Uniprot IDs		O95295	P54257
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Cytoskeleton Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Organelle Organization Intermediate Filament Organization Establishment Of Organelle Localization Intermediate Filament Supramolecular Fiber Organization Organelle Localization Structural Constituent Of Cytoskeleton BLOC-1 Complex Actin Filament Binding Synaptic Vesicle Transport Establishment Of Vesicle Localization Structural Molecule Activity Axo-dendritic Transport Axon Cytoplasm Axonal Transport Vesicle Localization Establishment Of Localization In Cell Anterograde Axonal Transport Cytosol Anterograde Synaptic Vesicle Transport Muscle Thin Filament Tropomyosin Structural Constituent Of Skin Epidermis Cytoplasm Transport Along Microtubule Vesicle Transport Along Microtubule Cellular Localization Cytoskeleton-dependent Intracellular Transport Vesicle Cytoskeletal Trafficking Regulation Of Cellular Component Organization Microtubule-based Transport Melanosome Organization Keratin Filament Intracellular Transport Pigment Granule Organization Structural Constituent Of Muscle Actomyosin Structure Organization Muscle System Process Actin Binding Muscle Contraction Extracellular Exosome Contractile Muscle Fiber Stress Fiber Organelle Transport Along Microtubule Tissue Morphogenesis Intracellular Protein Localization Z Disc	Nucleus Nucleoplasm Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Microtubule Nucleation Positive Regulation Of Microtubule Polymerization Regulation Of Primary Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Establishment Of Mitotic Spindle Localization Establishment Of Mitotic Spindle Orientation Mitotic Spindle Pole DNA Replication-dependent Chromatin Disassembly Establishment Of Spindle Orientation Regulation Of Microtubule Nucleation Chromatin Organization Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Protein Binding Regulation Of Metabolic Process Establishment Of Spindle Localization Positive Regulation Of Aggrephagy Protein Import Into Mitochondrial Matrix RNA Polymerase Transcription Factor SL1 Complex Histone Acetyltransferase Complex Spindle Localization Regulation Of Microtubule Polymerization Regulation Of Macromolecule Metabolic Process Establishment Of Organelle Localization Centriolar Satellite Male Pronucleus Troponin Complex Protein Acetylation Histone H4K16 Acetyltransferase Activity Gamma-tubulin Binding
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