SNAPIN and CEP170

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		SNAPIN	CEP170
Description		SNAP associated protein	centrosomal protein 170
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Vesicle Manchette Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Cytosol Synaptic Vesicle Membrane Secretory Granule Synaptic Vesicle Membrane BLOC-1 Complex Cytoplasmic Vesicle Synapse Perinuclear Region Of Cytoplasm Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm Microvesicle	Cytoplasm Centrosome Centriole Spindle Cytosol Cytoskeleton Microtubule Ciliary Basal Body Centriolar Subdistal Appendage
	Molecular Function	SNARE Binding Protein Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis Lysosome Organization Lysosomal Lumen Acidification Chemical Synaptic Transmission Neurotransmitter Secretion Anterograde Axonal Transport Retrograde Axonal Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Protein-containing Complex Localization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Melanosome Organization Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Protein Maturation Establishment Of Vesicle Localization Regulation Of Lysosome Size Neuron Cellular Homeostasis Organelle Transport Along Microtubule Terminal Button Organization Autophagosome Maturation Late Endosome To Lysosome Transport Positive Regulation Of Late Endosome To Lysosome Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Bronchopulmonary dysplasia ( 23897914) Chromium levels ( 26025379) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Estimated glomerular filtration rate ( 31015462) Lung cancer in ever smokers ( 28604730) Mental health study participation (completed survey) ( 31263887) Metabolite levels ( 23823483) Red cell distribution width ( 28957414 32888494) Schizophrenia ( 23974872) Smoking behaviour (cigarettes smoked per day) ( 31217584) Systemising ( 31508503)
Interacting Genes		103 interacting genes: ABI2 ACTN2 ATG14 ATP1A1 BANP BFSP1 BFSP2 BIN1 BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL C20orf202 CCDC102B CDC42BPA CEP170 CMYA5 CSNK1D DDR1 DENND1C DES DNM2 DOCK9 DST DTNBP1 DYRK3 DYSF EBAG9 EEF1G ELP1 ENO3 EXOC7 FAM114A1 FSD2 GPRASP1 GRIK1 HAP1 HMGB2 IKBIP IMMT KANK2 KAT5 KAT7 KIF5C KPNB1 KRT10 KRT15 KRT16 KRT17 KRT19 KRT20 KRT24 KRT26 LAMA2 LAMC1 LMNB1 LRP12 MACF1 MAPK14 MET MORC3 MTNR1A MYH14 MYH3 MYH7 NECAB2 NEDD9 NME7 NUP62CL PCYT1A PLAC9 PLEC PRKACA RABEP1 RABGEF1 RETREG1 RGS7 RNF13 SHBG SKA1 SMAD2 SMG1 SNAP23 SNAP25 SPAG5 SPP1 SPTB SPTBN1 ST7 TFIP11 TOMM70 TPM1 TPM2 TPM3 TPM4 TRIM63 TRPV1 TSG101 WASHC3 YWHAE YWHAZ	8 interacting genes: CEBPA NDEL1 PPP1CA PTEN SNAPIN SRPK2 VAV2 YWHAG
Entrez ID		23557	9859
HPRD ID		06111	17172
Ensembl ID		ENSG00000143553	ENSG00000143702
Uniprot IDs		O95295	Q5SW79
PDB IDs			4JON
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Cytoskeleton Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Organelle Organization Intermediate Filament Organization Establishment Of Organelle Localization Intermediate Filament Supramolecular Fiber Organization Organelle Localization Structural Constituent Of Cytoskeleton BLOC-1 Complex Actin Filament Binding Synaptic Vesicle Transport Establishment Of Vesicle Localization Structural Molecule Activity Axo-dendritic Transport Axon Cytoplasm Axonal Transport Vesicle Localization Establishment Of Localization In Cell Anterograde Axonal Transport Cytosol Anterograde Synaptic Vesicle Transport Muscle Thin Filament Tropomyosin Structural Constituent Of Skin Epidermis Cytoplasm Transport Along Microtubule Vesicle Transport Along Microtubule Cellular Localization Cytoskeleton-dependent Intracellular Transport Vesicle Cytoskeletal Trafficking Regulation Of Cellular Component Organization Microtubule-based Transport Melanosome Organization Keratin Filament Intracellular Transport Pigment Granule Organization Structural Constituent Of Muscle Actomyosin Structure Organization Muscle System Process Actin Binding Muscle Contraction Extracellular Exosome Contractile Muscle Fiber Stress Fiber Organelle Transport Along Microtubule Tissue Morphogenesis Intracellular Protein Localization Z Disc	Organelle Organization Developmental Maturation Intracellular Signaling Cassette Cellular Response To Xenobiotic Stimulus RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Developmental Process Presynapse Protein Stabilization Protein Dephosphorylation Phosphatase Activity Regulation Of Protein Stability RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Protein Serine/threonine Phosphatase Activity Cytosol Regulation Of Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of Synaptic Vesicle Clustering Regulation Of Cell Projection Organization Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Central Nervous System Neuron Axonogenesis Cell Migration Cell Projection Organization Microtubule-based Process Regulation Of Cellular Component Size Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell Size Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Vesicle Cytoskeletal Trafficking Retrograde Axonal Transport Positive Regulation Of Late Endosome To Lysosome Transport Vesicle Transport Along Microtubule Lysosome Localization Axon Cytoplasm Axonal Transport Axo-dendritic Transport Organelle Transport Along Microtubule Neurofilament Cytoskeleton Intracellular Signal Transduction Regulation Of Neuron Projection Development Lung Development Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Translational Initiation Negative Regulation Of Protein Phosphorylation Cell Motility Establishment Of Vesicle Localization CHOP-C/EBP Complex Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled
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