KIF1B and EEF1A1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KIF1B	EEF1A1
Description		kinesin family member 1B	eukaryotic translation elongation factor 1 alpha 1
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytoskeleton Kinesin Complex Microtubule Membrane Axon Dendrite Synaptic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Synapse Presynapse Postsynapse Axon Cytoplasm	Extracellular Region Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Ribosome Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Cytosolic Ribosome Cortical Actin Cytoskeleton Ruffle Membrane Secretory Granule Lumen Extracellular Exosome Cytoplasmic Side Of Lysosomal Membrane Ficolin-1-rich Granule Lumen
	Molecular Function	Nucleotide Binding Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity Isomerase Activity ATP Hydrolysis Activity Kinesin Binding	TRNA Binding Nucleotide Binding RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Hydrolase Activity Kinase Activator Activity Kinase Binding Protein Kinase Binding Molecular Adaptor Activity
	Biological Process	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Transport Along Microtubule Vesicle-mediated Transport Mitochondrion Transport Along Microtubule Anterograde Synaptic Vesicle Transport Apoptotic Process Involved In Development Retrograde Neuronal Dense Core Vesicle Transport	Translation Translational Elongation Host-mediated Activation Of Viral Genome Replication Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Chaperone-mediated Autophagy
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Eukaryotic Translation Elongation Eukaryotic Translation Elongation Peptide chain elongation HSF1 activation Neutrophil degranulation Protein methylation Chaperone Mediated Autophagy SARS-CoV-1 modulates host translation machinery
Drugs			Zinc Guanosine-5'-Diphosphate Copper Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Hand grip strength ( 29691431) Hematocrit ( 27863252) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Hepatocellular carcinoma ( 20676096) Hip circumference adjusted for BMI ( 34021172) Lateral orbital frontal cortex volume ( 31530798) Mean platelet volume ( 27863252 22139419 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 18997785) Neutrophil count ( 32888494) Platelet count ( 32888494) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 32888494)
Interacting Genes		25 interacting genes: ARHGAP1 BRCA1 CALM1 CHP1 CLIP4 CPEB1 DLG1 DLG2 DLG3 DLG4 DSCR4 DYSF EEF1A1 GIPC1 LAMTOR5 PATJ PGM1 PKNOX1 POMP RSPH1 SIAH1 SNTA1 STARD13 TRIM55 YWHAG	144 interacting genes: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 AQP2 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCL18 CDC25A CDKN1A CEBPA CKS2 CLIC6 COX17 CRADD CRCT1 CREBBP CSRP2 CTIF DARS1 DCTN1 DIABLO DLEU1 DNMT1 DNMT3A DUSP7 DYNLL1 DYSF EIF3F EP300 EXOSC4 FAS GADD45A GADD45G HOXA1 HSPB2 HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP OGT ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP PTPRF RAB27A RAP2A RFC5 RGS12 RND1 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB5 SERPINB9 SF3B4 SFN SHBG SMAD2 SMAD4 SMN1 SPATS2L SPP1 SSR1 STAT6 STMN2 SULT1E1 SUMO2 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSC2 TSPY1 TSPYL2 TTLL12 TTR TXNIP UBQLN4 USP40 VHL WARS1 WEE2-AS1 XPO5 XRN2 YJU2B YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1
Entrez ID		23095	1915
HPRD ID		05818	00559
Ensembl ID		ENSG00000054523	ENSG00000156508
Uniprot IDs		O60333	P68104 Q6IPS9
PDB IDs		2EH0	3C5J 6ZMO 8G60 8G6J
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Apical/basal Cell Polarity Kinase Binding Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuromuscular Junction Ionotropic Glutamate Receptor Binding Receptor Localization To Synapse Receptor Clustering Protein Localization To Synapse Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Establishment Or Maintenance Of Cell Polarity Cytoplasm Protein Localization To Cell Junction Postsynaptic Density Membrane Regulation Of Sodium Ion Transmembrane Transport Protein Kinase Binding Cytosol GMP Kinase Activity Chemical Synaptic Transmission Neuron Projection Trans-synaptic Signaling Regulation Of Sodium Ion Transport Cytoplasmic Microtubule Organization Synaptic Signaling GDP Metabolic Process Juxtaparanode Region Of Axon Adherens Junction Cellular Response To Potassium Ion Voltage-gated Potassium Channel Complex Ribonucleoside Diphosphate Metabolic Process Regulation Of Synaptic Plasticity Nucleoside Diphosphate Metabolic Process Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Intracellular Signal Transduction Negative Regulation Of Transport Response To Potassium Ion Postsynaptic Density Regulation Of Cell Communication Regulation Of Signaling Regulation Of Monoatomic Cation Transmembrane Transport Sarcolemma Protein K6-linked Ubiquitination Regulation Of Signal Transduction Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Biological Quality Modulation Of Chemical Synaptic Transmission GMP Metabolic Process AMPA Glutamate Receptor Complex Intracellular Signal Transduction Bicellular Tight Junction Regulation Of Monoatomic Ion Transmembrane Transport	Cytoplasm Apoptotic Process Cell Death Programmed Cell Death Regulation Of Programmed Cell Death Cytosol Negative Regulation Of Protein Kinase Activity Intracellular Signal Transduction Negative Regulation Of Kinase Activity Negative Regulation Of Metabolic Process Regulation Of Apoptotic Process Nucleic Acid Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Reactive Oxygen Species Metabolic Process Apoptotic Signaling Pathway BBSome Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling TORC1 Signaling Protein-containing Complex Nucleus Macromolecule Biosynthetic Process Melanosome Transport Tau Protein Binding Regulation Of Developmental Process RNA Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Establishment Of Melanosome Localization Pigment Granule Transport Negative Regulation Of Protein Phosphorylation Cellular Response To Stress Melanosome Localization Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Macromolecule Metabolic Process Positive Regulation Of Apoptotic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Pigment Granule Localization Mitochondrial Intermembrane Space Nucleoplasm Protein Binding Negative Regulation Of Catalytic Activity Histone H3K27 Acetyltransferase Activity Negative Regulation Of Phosphate Metabolic Process TOR Signaling Positive Regulation Of TOR Signaling Regulation Of Phosphorus Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?