KIF1B and CLIP4

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		KIF1B	CLIP4
Description		kinesin family member 1B	CAP-Gly domain containing linker protein family member 4
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytoskeleton Kinesin Complex Microtubule Membrane Axon Dendrite Synaptic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Synapse Presynapse Postsynapse Axon Cytoplasm	Nucleus Cell Cortex Microtubule Plus-end
	Molecular Function	Nucleotide Binding Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity Isomerase Activity ATP Hydrolysis Activity Kinesin Binding	Protein Binding Microtubule Plus-end Binding
	Biological Process	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Transport Along Microtubule Vesicle-mediated Transport Mitochondrion Transport Along Microtubule Anterograde Synaptic Vesicle Transport Apoptotic Process Involved In Development Retrograde Neuronal Dense Core Vesicle Transport	Cytoplasmic Microtubule Organization
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Hand grip strength ( 29691431) Hematocrit ( 27863252) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Hepatocellular carcinoma ( 20676096) Hip circumference adjusted for BMI ( 34021172) Lateral orbital frontal cortex volume ( 31530798) Mean platelet volume ( 27863252 22139419 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 18997785) Neutrophil count ( 32888494) Platelet count ( 32888494) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 32888494)	Metabolite levels ( 23823483)
Interacting Genes		25 interacting genes: ARHGAP1 BRCA1 CALM1 CHP1 CLIP4 CPEB1 DLG1 DLG2 DLG3 DLG4 DSCR4 DYSF EEF1A1 GIPC1 LAMTOR5 PATJ PGM1 PKNOX1 POMP RSPH1 SIAH1 SNTA1 STARD13 TRIM55 YWHAG	37 interacting genes: APP CDK5RAP2 CLIP1 CMYA5 DCAF6 DES DST DYNC2LI1 GLP1R HSF2BP JAKMIP2 KIF1B KIFC3 LZTS2 MAGEA12 MAP7 MAP7D1 MEOX2 MYBPC1 MYH3 PDE4DIP PEG10 RPS13 RPS27L RUNX1 SIX2 SON TACC3 TAF1 TNNT1 TNNT3 TPM1 TRIM32 TRIP13 TTN TULP3 ZNF114
Entrez ID		23095	79745
HPRD ID		05818	08634
Ensembl ID		ENSG00000054523	ENSG00000115295
Uniprot IDs		O60333	A0A8I5KXU9 A0A8I5QKP4 A0A8I5QKV0 A8K6D0 B7Z936 G3XAK3 Q8N3C7
PDB IDs		2EH0	2Z0W
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Apical/basal Cell Polarity Kinase Binding Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuromuscular Junction Ionotropic Glutamate Receptor Binding Receptor Localization To Synapse Receptor Clustering Protein Localization To Synapse Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Establishment Or Maintenance Of Cell Polarity Cytoplasm Protein Localization To Cell Junction Postsynaptic Density Membrane Regulation Of Sodium Ion Transmembrane Transport Protein Kinase Binding Cytosol GMP Kinase Activity Chemical Synaptic Transmission Neuron Projection Trans-synaptic Signaling Regulation Of Sodium Ion Transport Cytoplasmic Microtubule Organization Synaptic Signaling GDP Metabolic Process Juxtaparanode Region Of Axon Adherens Junction Cellular Response To Potassium Ion Voltage-gated Potassium Channel Complex Ribonucleoside Diphosphate Metabolic Process Regulation Of Synaptic Plasticity Nucleoside Diphosphate Metabolic Process Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Intracellular Signal Transduction Negative Regulation Of Transport Response To Potassium Ion Postsynaptic Density Regulation Of Cell Communication Regulation Of Signaling Regulation Of Monoatomic Cation Transmembrane Transport Sarcolemma Protein K6-linked Ubiquitination Regulation Of Signal Transduction Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Biological Quality Modulation Of Chemical Synaptic Transmission GMP Metabolic Process AMPA Glutamate Receptor Complex Intracellular Signal Transduction Bicellular Tight Junction Regulation Of Monoatomic Ion Transmembrane Transport	Cytoskeleton Organization Sarcomere Organization Organelle Organization Microtubule-based Process Microtubule Cytoskeleton Organization Actomyosin Structure Organization Microtubule Skeletal Muscle Contraction Striated Muscle Contraction Microtubule Binding Muscle Filament Sliding Muscle Contraction Actin-myosin Filament Sliding Centrosome Actin Cytoskeleton Organization Cytoskeleton Microtubule Plus-end Microtubule Cytoskeleton Muscle System Process M Band Actin Filament-based Process Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Microtubule Polymerization Actin-mediated Cell Contraction Female Meiosis I Structural Constituent Of Muscle Troponin Complex Myofibril Male Meiotic Nuclear Division Regulation Of Supramolecular Fiber Organization Actin Filament-based Movement Contractile Muscle Fiber Tropomyosin Binding Regulation Of Microtubule Polymerization Cytoskeletal Protein Binding Regulation Of Microtubule Cytoskeleton Organization Transport Along Microtubule Meiotic Nuclear Division Female Meiotic Nuclear Division Axo-dendritic Transport Positive Regulation Of Cytoskeleton Organization Supramolecular Fiber Organization Retrograde Axonal Transport Microtubule Plus-end Binding Positive Regulation Of Protein Polymerization Cytoskeleton-dependent Intracellular Transport Myosin Filament Nuclear Division Regulation Of Cytoskeleton Organization Amyloid-beta Complex
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