Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
CACNA1A and SUMF2
Number of citations of the paper that reports this interaction (PMID
21078624
)
14
Data Source:
BioGRID
(two hybrid)
CACNA1A
SUMF2
Gene Name
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
sulfatase modifying factor 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Voltage-gated Calcium Channel Complex
Integral Component Of Membrane
Dendrite
Cell Projection
Neuronal Cell Body
Endoplasmic Reticulum Lumen
Molecular Function
Voltage-gated Calcium Channel Activity
Protein Binding
High Voltage-gated Calcium Channel Activity
Syntaxin Binding
Metal Ion Binding
Metal Ion Binding
Biological Process
Sulfur Amino Acid Metabolic Process
Glucose Metabolic Process
Energy Reserve Metabolic Process
Positive Regulation Of Cytosolic Calcium Ion Concentration
Gamma-aminobutyric Acid Signaling Pathway
Synaptic Transmission
Neuromuscular Synaptic Transmission
Synapse Assembly
Adult Walking Behavior
Cell Death
Gamma-aminobutyric Acid Secretion
Regulation Of Acetylcholine Secretion, Neurotransmission
Cell Growth
Calcium Ion-dependent Exocytosis
Regulation Of Calcium Ion-dependent Exocytosis
Transmission Of Nerve Impulse
Spinal Cord Motor Neuron Differentiation
Cerebellum Maturation
Cerebellar Molecular Layer Development
Cerebellar Purkinje Cell Differentiation
Vestibular Nucleus Development
Cellular Chloride Ion Homeostasis
Negative Regulation Of Hormone Biosynthetic Process
Regulation Of Ion Transmembrane Transport
Synaptic Transmission, Glutamatergic
Neurotransmitter Metabolic Process
Hormone Metabolic Process
Receptor Clustering
Negative Regulation Of Neuron Apoptotic Process
Small Molecule Metabolic Process
Behavioral Response To Pain
Calcium Ion-dependent Exocytosis Of Neurotransmitter
Dendrite Morphogenesis
Regulation Of Axonogenesis
Regulation Of Insulin Secretion
Musculoskeletal Movement, Spinal Reflex Action
Neuromuscular Process Controlling Balance
Membrane Depolarization
Rhythmic Synaptic Transmission
Calcium Ion Import
Calcium Ion Transmembrane Transport
Membrane Depolarization During Action Potential
Post-translational Protein Modification
Cellular Protein Metabolic Process
Pathways
Integration of energy metabolism
Regulation of insulin secretion
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels
Transmission across Chemical Synapses
Sphingolipid metabolism
Metabolism of lipids and lipoproteins
Glycosphingolipid metabolism
Post-translational protein modification
The activation of arylsulfatases
Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs
Pregabalin
Verapamil
Loperamide
Bepridil
Diseases
GWAS
Protein-Protein Interactions
92 interactors:
ABCA2
ABI1
ACTN1
AGRN
ALDOA
AMIGO2
AP2M1
ARHGAP22
ASNA1
BTG3
BZRAP1
C1QTNF1
CABP1
CACNB1
CACNB4
CALM2
CALM3
CKAP5
CRIM1
CRMP1
CSNK2B
CYSRT1
DNAJB5
EFEMP1
EFEMP2
EHMT2
EIF3A
FBLN1
GNB1
GOLGA6L5P
GRN
HECW1
HHATL
HIVEP1
HSPG2
IP6K1
JAG2
KALRN
KHDRBS3
KIAA1191
LAMB1
LLGL1
LPHN1
LRP1
LTBP1
LTBP3
LTBP4
MANBAL
MATK
MATN2
MEGF6
MEGF8
MIA3
MOAP1
NDUFB8
NELFCD
NELL1
NELL2
NOTCH1
NOXA1
OLIG1
PCSK5
PCSK6
PMM1
PPIG
PPM1A
PPP1R12C
PTGDS
PUF60
RBM12B
RIMBP2
RPL31
RPS17
SCP2
SPRY1
SRRM4
SRSF1
SUMF2
SYT1
TAF15
TELO2
TSC22D1
TSPAN7
TUBB2B
UQCRC2
VARS
VPS52
VWF
WBP1
YLPM1
ZCCHC17
ZNF233
4 interactors:
CACNA1A
FBXW7
ZDHHC17
ZFYVE9
Entrez ID
773
25870
HPRD ID
03004
06400
Ensembl ID
ENSG00000141837
ENSG00000129103
Uniprot IDs
B5TYJ1
O00555
Q9NS89
Q8NBJ7
PDB IDs
3BXK
1Y4J
Enriched GO Terms of Interacting Partners
?
Secretion By Cell
Secretion
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Voltage-gated Calcium Channel Activity
Detection Of Visible Light
Enzyme Linked Receptor Protein Signaling Pathway
Detection Of Light Stimulus
Multicellular Organismal Development
Phototransduction, Visible Light
Anatomical Structure Development
Cellular Localization
Axon Development
Developmental Process
Establishment Of Localization In Cell
Phototransduction
Regulation Of Cellular Process
System Development
Axonogenesis
Regulation Of Calcium Ion Transmembrane Transport
Regulation Of Calcium Ion Transmembrane Transporter Activity
Detection Of Abiotic Stimulus
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Platelet Degranulation
Cell Morphogenesis Involved In Neuron Differentiation
Anatomical Structure Morphogenesis
Regulation Of Cation Channel Activity
Axon Guidance
Nervous System Development
Detection Of Calcium Ion
Regulation Of Intracellular Cholesterol Transport
Regulation Of Cell Communication By Electrical Coupling
Neuron Projection Morphogenesis
Exocytosis
Neuron Projection Development
Cellular Response To Growth Factor Stimulus
Neuron Differentiation
Inositol Phosphate Metabolic Process
Cell Projection Morphogenesis
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Cell Morphogenesis Involved In Differentiation
Cell Part Morphogenesis
Response To Growth Factor
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Cation Channel Activity
Platelet Activation
Cell-cell Signaling
Nerve Growth Factor Processing
Pathogenesis
Neurotrophin TRK Receptor Signaling Pathway
Cerebellar Molecular Layer Development
Negative Regulation Of SREBP Signaling Pathway
Regulation Of Signaling
Negative Regulation Of Triglyceride Biosynthetic Process
Vestibular Nucleus Development
Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Cerebellum Maturation
Musculoskeletal Movement, Spinal Reflex Action
Regulation Of Neuron Apoptotic Process
Negative Regulation Of Hepatocyte Proliferation
Gamma-aminobutyric Acid Secretion
Negative Regulation Of DNA Endoreduplication
Regulation Of Acetylcholine Secretion, Neurotransmission
Regulation Of Neuron Death
Rhythmic Synaptic Transmission
Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Oxidative Stress-induced Cell Death
Calcium Ion-dependent Exocytosis Of Neurotransmitter
Cellular Chloride Ion Homeostasis
SMAD Protein Import Into Nucleus
Gamma-aminobutyric Acid Transport
Chloride Ion Homeostasis
Regulation Of DNA Endoreduplication
Regulation Of Hepatocyte Proliferation
Negative Regulation Of Hormone Biosynthetic Process
Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity
Pons Development
SMAD Protein Complex Assembly
Protein Localization
Signal Transduction
Cerebellar Purkinje Cell Differentiation
Cerebellar Purkinje Cell Layer Morphogenesis
Regulation Of Triglyceride Biosynthetic Process
Signaling
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Lipoprotein Transport
Magnesium Ion Transport
Cell Communication
Reflex
Behavioral Response To Pain
Positive Regulation Of ERBB Signaling Pathway
Neuromuscular Synaptic Transmission
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Hormone Biosynthetic Process
Cerebellar Cortex Formation
Neurotransmitter Metabolic Process
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Sister Chromatid Cohesion
Protein Palmitoylation
Tagcloud
?
acetazolamide
ataxia
attacks
autosomal
causative
causing
coincidence
confutes
defect
dysarthria
dystonia
ea
ea2
encodes
episodes
episodic
gait
gated
heterogeneous
inherited
migraine
mim
nonsense
oculomotor
paroxysmal
q
varied
voltage
Tagcloud (Difference)
?
acetazolamide
ataxia
attacks
autosomal
causative
causing
coincidence
confutes
defect
dysarthria
dystonia
ea
ea2
encodes
episodes
episodic
gait
gated
heterogeneous
inherited
migraine
mim
nonsense
oculomotor
paroxysmal
q
varied
voltage
Tagcloud (Intersection)
?