YPEL3 and TP53INP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YPEL3	TP53INP1
Description		yippee like 3	tumor protein p53 inducible nuclear protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus	Nucleus Nucleoplasm Cytoplasm Autophagosome Cytosol PML Body Cytoplasmic Vesicle
	Molecular Function	Metal Ion Binding	Protein Binding Antioxidant Activity
	Biological Process	Positive Regulation Of Cellular Senescence	Autophagosome Assembly Autophagy Apoptotic Process Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Autophagy Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Cellular Response To UV Positive Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Autophagic Cell Death Negative Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Cellular Response To Ethanol Cellular Response To Hydroperoxide Cellular Response To Methyl Methanesulfonate Cellular Oxidant Detoxification Negative Regulation Of Myofibroblast Differentiation
Pathways			TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 25056061 28991256 29483656)	Alzheimer's disease ( 31473137) Fasting glucose ( 34059833) Hemoglobin levels ( 32327693) Intraocular pressure ( 29617998) Keratoconus ( 33649486) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Macular thickness ( 30535121) Platelet distribution width ( 32888494) Serum uric acid levels ( 30993211 29403010) Type 2 diabetes ( 20581827 30297969 30054458 32499647 28869590 24509480 22885922) Urate levels ( 31578528)
Interacting Genes		122 interacting genes: ACTMAP AIRIM APP ARMC7 ATG9A ATXN1L BCAS2 C10orf55 CABP2 CDCA4 CDKN2D COL8A1 CRYBA1 CRYBA2 CYB5R2 CYSRT1 DMRT3 DOK6 DOK7 EID2B FAM168B FANCL FGF21 FHL2 FHL3 FHL5 FNDC3B FRS3 GCA GCM2 GEM GUCD1 HDAC7 HEXIM2 HGS HNRNPH1 HOXA1 HR HSD3B7 HSPB2 HSPB2-C11orf52 INTS11 KLHL38 KRTAP13-2 KRTAP15-1 KRTAP23-1 KRTAP3-1 KRTAP3-3 KRTAP6-2 LARP4 LIMS3 LIMS4 LMO2 LONRF1 MAD2L2 MDFI MKRN3 MORN3 MYOZ1 MYOZ3 NRF1 NUFIP2 ODAM OSTF1 OTX1 PIK3R3 PITX1 PLSCR4 POLD1 POLR1C POU2AF1 PPP2CA PRKAA2 PRKAB2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 QRICH1 RBPMS RFC5 SH2D4A SHC3 SMUG1 SPAG8 SPG21 SPRYD7 SRPK2 STK16 TASOR2 TBX6 TENT5A TENT5B TEPSIN TGM7 TLE5 TLX3 TOX2 TP53INP1 TRAPPC2L TRAPPC6A TRIM10 TRIM55 TRIM63 TRIM73 TRIP6 TSC1 TSSK3 UBASH3A UBTD2 VENTX VGLL3 VWC2L WWOX ZIC1 ZNF441 ZNF76 ZNF765 ZYX	11 interacting genes: GABARAP GABARAPL1 GABARAPL2 HIPK2 MAP1LC3A MAP1LC3C SEC22A SQSTM1 TP53 UNC119 YPEL3
Entrez ID		83719	94241
HPRD ID		15683	09367
Ensembl ID		ENSG00000090238	ENSG00000164938
Uniprot IDs		P61236	Q96A56
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus	Mitophagy Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Macroautophagy Autophagosome Autophagosome Maturation Ubiquitin Protein Ligase Binding Autophagy Autophagosome Membrane Cellular Response To Starvation Response To Starvation Autophagosome Assembly Autophagosome Organization Cellular Response To Nutrient Levels Phospholipid Binding Protein-containing Complex Disassembly Vacuole Organization GABA Receptor Binding Response To Nutrient Levels Cellular Response To Stress Protein Transport Organelle Assembly Beta-tubulin Binding Establishment Of Protein Localization Cytoplasmic Vesicle Organelle Organization Autolysosome Intracellular Protein Localization Aggrephagy PML Body Positive Regulation Of Cellular Senescence Microtubule Catabolic Process Regulation Of Proteolysis Cellular Response To Decreased Oxygen Levels Negative Regulation Of Proteolysis Protein-containing Complex Organization SMAD Protein Signal Transduction Cytoskeleton Response To Stress Cellular Response To Oxygen Levels Regulation Of Protein Metabolic Process Regulation Of ATP-dependent Activity Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Cellular Component Assembly Organelle Membrane Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Senescence DNA Damage Response, Signal Transduction By P53 Class Mediator
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