YPEL3 and GCM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YPEL3	GCM2
Description		yippee like 3	glial cells missing transcription factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus	Chromatin Nucleus
	Molecular Function	Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Cellular Senescence	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Intracellular Calcium Ion Homeostasis Intracellular Phosphate Ion Homeostasis Gliogenesis Positive Regulation Of Transcription By RNA Polymerase II Parathyroid Gland Development
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 25056061 28991256 29483656)	Menarche and menopause (age at onset) ( 19448621) Metabolite levels ( 23823483) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		122 interacting genes: ACTMAP AIRIM APP ARMC7 ATG9A ATXN1L BCAS2 C10orf55 CABP2 CDCA4 CDKN2D COL8A1 CRYBA1 CRYBA2 CYB5R2 CYSRT1 DMRT3 DOK6 DOK7 EID2B FAM168B FANCL FGF21 FHL2 FHL3 FHL5 FNDC3B FRS3 GCA GCM2 GEM GUCD1 HDAC7 HEXIM2 HGS HNRNPH1 HOXA1 HR HSD3B7 HSPB2 HSPB2-C11orf52 INTS11 KLHL38 KRTAP13-2 KRTAP15-1 KRTAP23-1 KRTAP3-1 KRTAP3-3 KRTAP6-2 LARP4 LIMS3 LIMS4 LMO2 LONRF1 MAD2L2 MDFI MKRN3 MORN3 MYOZ1 MYOZ3 NRF1 NUFIP2 ODAM OSTF1 OTX1 PIK3R3 PITX1 PLSCR4 POLD1 POLR1C POU2AF1 PPP2CA PRKAA2 PRKAB2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 QRICH1 RBPMS RFC5 SH2D4A SHC3 SMUG1 SPAG8 SPG21 SPRYD7 SRPK2 STK16 TASOR2 TBX6 TENT5A TENT5B TEPSIN TGM7 TLE5 TLX3 TOX2 TP53INP1 TRAPPC2L TRAPPC6A TRIM10 TRIM55 TRIM63 TRIM73 TRIP6 TSC1 TSSK3 UBASH3A UBTD2 VENTX VGLL3 VWC2L WWOX ZIC1 ZNF441 ZNF76 ZNF765 ZYX	34 interacting genes: CEACAM6 CRX DOK3 ECM1 FHL3 GPSM1 GSC2 HOXA1 HSF2BP HSFY1 HSFY2 JMJD7 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 LHX3 MEOX2 MYOZ3 PAX6 PAX8 PLEKHG4 POU6F2 RBPMS RUSC1 SSBP1 TBX19 TOX3 TRAF1 USP54 WWOX YPEL3 ZMIZ2 ZNF34
Entrez ID		83719	9247
HPRD ID		15683	04758
Ensembl ID		ENSG00000090238	ENSG00000124827
Uniprot IDs		P61236	O75603
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus	DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Sequence-specific Double-stranded DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process DNA Binding Sequence-specific DNA Binding Pituitary Gland Development Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Inner Ear Development Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Fate Specification Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process SMAD Protein Signal Transduction
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