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LNX2 and UBE2T
Number of citations of the paper that reports this interaction (PMID
19549727
)
40
Data Source:
BioGRID
(two hybrid)
LNX2
UBE2T
Gene Name
ligand of numb-protein X 2
ubiquitin-conjugating enzyme E2T
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Protein Binding
Zinc Ion Binding
PDZ Domain Binding
Chromatin Binding
Ubiquitin-protein Transferase Activity
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Homooligomerization
DNA Repair
Protein Monoubiquitination
Cellular Response To DNA Damage Stimulus
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Pathways
Fanconi Anemia pathway
Drugs
Diseases
GWAS
Large B-cell lymphoma (
21471979
)
Breast cancer (
23535733
)
Protein-Protein Interactions
17 interactors:
CBX4
CXADR
HOXA1
IGSF5
LNX1
MDGA1
NUMB
PDZRN3
PDZRN4
PKDREJ
RLIM
RNF138
SHISA2
UBE2I
UBE2T
UBE2Z
USP2
14 interactors:
AMFR
ARIH2
BRCA1
FANCL
LNX2
MARCH5
MGRN1
PCGF2
RNF128
RNF144B
RNF4
TRIM27
UBA1
UBA6
Entrez ID
222484
29089
HPRD ID
10042
13704
Ensembl ID
ENSG00000139517
ENSG00000077152
Uniprot IDs
Q8N448
Q9NPD8
PDB IDs
2VWR
1YH2
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Cellular Protein Modification Process
Protein Sumoylation
Cellular Protein Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Optokinetic Behavior
Abducens Nerve Formation
Random Inactivation Of X Chromosome
Positive Regulation Of SUMO Transferase Activity
Protein Catabolic Process
Facial Nucleus Development
Positive Regulation Of Polarized Epithelial Cell Differentiation
Protein Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Rhombomere 4 Development
Semicircular Canal Formation
Cellular Macromolecule Catabolic Process
Rhombomere 3 Development
Rhombomere 5 Development
Neuroblast Division In Subventricular Zone
Protein K27-linked Ubiquitination
Protein K29-linked Ubiquitination
AV Node Cell To Bundle Of His Cell Communication
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Protein K63-linked Ubiquitination
Protein Autoubiquitination
Cellular Macromolecule Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Protein K6-linked Ubiquitination
Proteolysis
Cellular Metabolic Process
Protein K48-linked Ubiquitination
Androgen Receptor Signaling Pathway
Protein Monoubiquitination
Catabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Intracellular Steroid Hormone Receptor Signaling Pathway
Cellular Response To Stress
Regulation Of Kinetochore Assembly
Negative Regulation Of Interleukin-2 Secretion
Positive Regulation Of Histone H3-K9 Acetylation
Positive Regulation Of Organelle Organization
Regulation Of Organelle Organization
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Regulation Of Centromere Complex Assembly
Protein Oligomerization
Regulation Of Cytoskeleton Organization
Cellular Response To Indole-3-methanol
Regulation Of Microtubule Cytoskeleton Organization
Negative Regulation Of Centriole Replication
Negative Regulation Of Calcium Ion Import
Regulation Of Cytokine Production
Dosage Compensation By Inactivation Of X Chromosome
Regulation Of Microtubule-based Process
Negative Regulation Of CAMP-mediated Signaling
Interferon-gamma Secretion
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Histone H3-K9 Methylation
Dosage Compensation
Regulation Of Histone H3-K9 Acetylation
Metabolic Process
Tagcloud
?
amplicons
aneuploidy
behind
candidates
colorectal
copy
crc
dis3
downregulated
drivers
gains
gpr180
imbalances
klf5
landscape
mapping
notch
nupl1
offering
oncogene
polr1d
pomp
profiling
rnai
silencing
slc7a1
tcf7l2
unfinished
wnt
Tagcloud (Difference)
?
amplicons
aneuploidy
behind
candidates
colorectal
copy
crc
dis3
downregulated
drivers
gains
gpr180
imbalances
klf5
landscape
mapping
notch
nupl1
offering
oncogene
polr1d
pomp
profiling
rnai
silencing
slc7a1
tcf7l2
unfinished
wnt
Tagcloud (Intersection)
?