LNX2 and IGSF5

Number of citations of the paper that reports this interaction (PMID 16832352)
5

Data Source:
BioGRID (two hybrid)

		LNX2	IGSF5
Gene Name		ligand of numb-protein X 2	immunoglobulin superfamily, member 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Plasma Membrane Cell-cell Junction Tight Junction Cell Surface Integral Component Of Membrane Neuron Projection Neuronal Cell Body
	Molecular Function	Protein Binding Zinc Ion Binding PDZ Domain Binding	PDZ Domain Binding
	Biological Process	Protein Homooligomerization	Single Organismal Cell-cell Adhesion Regulation Of Neurogenesis
Pathways
Drugs
Diseases
GWAS		Large B-cell lymphoma ( 21471979)	Coronary heart disease ( 21347282)
Protein-Protein Interactions		17 interactors: CBX4 CXADR HOXA1 IGSF5 LNX1 MDGA1 NUMB PDZRN3 PDZRN4 PKDREJ RLIM RNF138 SHISA2 UBE2I UBE2T UBE2Z USP2	3 interactors: LNX1 LNX2 MAGI1
Entrez ID		222484	150084
HPRD ID		10042	19125
Ensembl ID		ENSG00000139517	ENSG00000183067
Uniprot IDs		Q8N448	Q9NSI5
PDB IDs		2VWR
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Sumoylation Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Optokinetic Behavior Abducens Nerve Formation Random Inactivation Of X Chromosome Positive Regulation Of SUMO Transferase Activity Protein Catabolic Process Facial Nucleus Development Positive Regulation Of Polarized Epithelial Cell Differentiation Protein Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere 4 Development Semicircular Canal Formation Cellular Macromolecule Catabolic Process Rhombomere 3 Development Rhombomere 5 Development Neuroblast Division In Subventricular Zone Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination AV Node Cell To Bundle Of His Cell Communication	Protein Complex Assembly Protein Homooligomerization Cellular Component Assembly Protein Oligomerization Negative Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Sodium Ion Transport Negative Regulation Of ERK1 And ERK2 Cascade Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Neuron Death Regulation Of Sodium Ion Transport
Tagcloud ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Difference) ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Intersection) ?