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UBE2T and AMFR
Number of citations of the paper that reports this interaction (PMID
19690564
)
33
Data Source:
BioGRID
(two hybrid)
UBE2T
AMFR
Gene Name
ubiquitin-conjugating enzyme E2T
autocrine motility factor receptor, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Hrd1p Ubiquitin Ligase Complex
Nucleus
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Dendrite
Growth Cone
Neuronal Cell Body
Protein Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Ubiquitin-protein Transferase Activity
Receptor Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Activity
Biological Process
DNA Repair
Protein Monoubiquitination
Cellular Response To DNA Damage Stimulus
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Movement Of Cell Or Subcellular Component
Signal Transduction
Aging
Learning Or Memory
ER-associated Ubiquitin-dependent Protein Catabolic Process
Endoplasmic Reticulum Unfolded Protein Response
Protein Oligomerization
Pathways
Fanconi Anemia pathway
Drugs
Diseases
GWAS
Breast cancer (
23535733
)
Protein-Protein Interactions
14 interactors:
AMFR
ARIH2
BRCA1
FANCL
LNX2
MARCH5
MGRN1
PCGF2
RNF128
RNF144B
RNF4
TRIM27
UBA1
UBA6
26 interactors:
BAG6
CRMP1
CYP2E1
CYP3A4
DERL1
DHFR
GPI
HERPUD1
HTT
KPNB1
SOD1
SYVN1
TOM1L1
TRIM25
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2G1
UBE2G2
UBE2K
UBE2N
UBE2T
UBE2W
UFD1L
VCP
Entrez ID
29089
267
HPRD ID
13704
09130
Ensembl ID
ENSG00000077152
ENSG00000159461
Uniprot IDs
Q9NPD8
Q9UKV5
PDB IDs
1YH2
2EJS
2LVN
2LVO
2LVP
2LVQ
2LXH
2LXP
3FSH
3H8K
3TIW
4G3O
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Protein K63-linked Ubiquitination
Protein Autoubiquitination
Cellular Macromolecule Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Protein K6-linked Ubiquitination
Proteolysis
Cellular Metabolic Process
Protein K48-linked Ubiquitination
Androgen Receptor Signaling Pathway
Protein Monoubiquitination
Catabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Intracellular Steroid Hormone Receptor Signaling Pathway
Cellular Response To Stress
Regulation Of Kinetochore Assembly
Negative Regulation Of Interleukin-2 Secretion
Positive Regulation Of Histone H3-K9 Acetylation
Positive Regulation Of Organelle Organization
Regulation Of Organelle Organization
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Regulation Of Centromere Complex Assembly
Protein Oligomerization
Regulation Of Cytoskeleton Organization
Cellular Response To Indole-3-methanol
Regulation Of Microtubule Cytoskeleton Organization
Negative Regulation Of Centriole Replication
Negative Regulation Of Calcium Ion Import
Regulation Of Cytokine Production
Dosage Compensation By Inactivation Of X Chromosome
Regulation Of Microtubule-based Process
Negative Regulation Of CAMP-mediated Signaling
Interferon-gamma Secretion
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Histone H3-K9 Methylation
Dosage Compensation
Regulation Of Histone H3-K9 Acetylation
Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Catabolic Process
Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteolysis
Proteasomal Protein Catabolic Process
Cellular Metabolic Process
Cellular Response To Stress
Protein K11-linked Ubiquitination
Cellular Protein Metabolic Process
Response To Endoplasmic Reticulum Stress
Response To Stress
Protein K63-linked Ubiquitination
Response To Organic Substance
ER-associated Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Topologically Incorrect Protein
Cellular Response To Organic Substance
Response To Stimulus
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Metabolic Process
Protein Metabolic Process
Cellular Protein Modification Process
Toll-like Receptor 4 Signaling Pathway
Regulation Of Proteasomal Protein Catabolic Process
Cellular Response To Stimulus
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Unfolded Protein
ER-nucleus Signaling Pathway
Apoptotic Process
Toll-like Receptor Signaling Pathway
Programmed Cell Death
Cell Death
Death
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Retrograde Protein Transport, ER To Cytosol
Response To Unfolded Protein
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Protein Monoubiquitination
Monoterpenoid Metabolic Process
Tagcloud
?
anchoring
catalyzed
dnas
e3
eris
facilitating
herpes
hsv
insig1
interacted
k27
ligase
microbial
microsomes
missing
mita
mpys
perinuclear
platform
polyubiquitination
recruiting
revealing
served
simplex
stimulator
sting
tank
tbk1
uncovers
Tagcloud (Difference)
?
anchoring
catalyzed
dnas
e3
eris
facilitating
herpes
hsv
insig1
interacted
k27
ligase
microbial
microsomes
missing
mita
mpys
perinuclear
platform
polyubiquitination
recruiting
revealing
served
simplex
stimulator
sting
tank
tbk1
uncovers
Tagcloud (Intersection)
?