LNX2 and CXADR

Number of citations of the paper that reports this interaction (PMID 22889411)
1

Data Source:
BioGRID (two hybrid)

		LNX2	CXADR
Gene Name		ligand of numb-protein X 2	coxsackie virus and adenovirus receptor
Image
Gene Ontology Annotations	Cellular Component		Acrosomal Vesicle Extracellular Region Extracellular Space Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Adherens Junction Tight Junction Intercalated Disc Basolateral Plasma Membrane Apicolateral Plasma Membrane Cell Junction Filopodium Growth Cone Neuromuscular Junction Neuron Projection Protein Complex Cell Body Membrane Raft
	Molecular Function	Protein Binding Zinc Ion Binding PDZ Domain Binding	Virus Receptor Activity Receptor Binding Integrin Binding Protein Binding Beta-catenin Binding PDZ Domain Binding Identical Protein Binding Cell Adhesion Molecule Binding Connexin Binding
	Biological Process	Protein Homooligomerization	Mitochondrion Organization Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Heart Development Blood Coagulation Germ Cell Migration Response To Virus Epithelial Structure Maintenance Viral Process Neutrophil Chemotaxis Actin Cytoskeleton Reorganization Homotypic Cell-cell Adhesion Cell-cell Junction Organization Gamma-delta T Cell Activation Cardiac Muscle Fiber Development Regulation Of Immune Response Leukocyte Migration Defense Response To Virus Transepithelial Transport AV Node Cell To Bundle Of His Cell Communication
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall Adaptive Immune System
Drugs
Diseases
GWAS		Large B-cell lymphoma ( 21471979)
Protein-Protein Interactions		17 interactors: CBX4 CXADR HOXA1 IGSF5 LNX1 MDGA1 NUMB PDZRN3 PDZRN4 PKDREJ RLIM RNF138 SHISA2 UBE2I UBE2T UBE2Z USP2	7 interactors: AMICA1 EWSR1 LNX1 LNX2 NCOA1 NCOR1 VKORC1
Entrez ID		222484	1525
HPRD ID		10042	11804
Ensembl ID		ENSG00000139517	ENSG00000154639
Uniprot IDs		Q8N448	P78310
PDB IDs		2VWR	1EAJ 1F5W 1JEW 1KAC 1P69 1P6A 1RSF 2J12 2J1K 2NPL 2W9L 2WBW
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Sumoylation Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Optokinetic Behavior Abducens Nerve Formation Random Inactivation Of X Chromosome Positive Regulation Of SUMO Transferase Activity Protein Catabolic Process Facial Nucleus Development Positive Regulation Of Polarized Epithelial Cell Differentiation Protein Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere 4 Development Semicircular Canal Formation Cellular Macromolecule Catabolic Process Rhombomere 3 Development Rhombomere 5 Development Neuroblast Division In Subventricular Zone Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination AV Node Cell To Bundle Of His Cell Communication	Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Monocyte Extravasation Diencephalon Development Regulation Of Body Fluid Levels Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Response To Drug CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Neutrophil Extravasation Regulation Of Response To Drug Gamma-delta T Cell Activation Definitive Erythrocyte Differentiation Regulatory T Cell Differentiation Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Positive Regulation Of Female Receptivity Vitamin K Metabolic Process Male Mating Behavior Protein Homooligomerization Carbon Catabolite Regulation Of Transcription Protein Complex Assembly T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Rhythmic Process Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Peptidyl-glutamic Acid Carboxylation Thalamus Development Regulation Of Female Receptivity Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Female Mating Behavior Lymphocyte Activation Positive Regulation Of Histone Deacetylation Blood Coagulation Hemostasis Protein Oligomerization Forebrain Development Definitive Hemopoiesis Labyrinthine Layer Morphogenesis Positive Regulation Of Protein Deacetylation Hypothalamus Development Regulation Of Glycolytic Process Leukocyte Activation Embryonic Placenta Morphogenesis Cellular Extravasation
Tagcloud ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt	biotin breeding btb car cko claudin coxsackievirus fertile fertility fertilize jam junctional knocking lanthanum litter occludin p49 p9 physiology pubertal pups spermatogenesis testicular testis timepoint tracers ultra uncompromised zo1
Tagcloud (Difference) ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt	biotin breeding btb car cko claudin coxsackievirus fertile fertility fertilize jam junctional knocking lanthanum litter occludin p49 p9 physiology pubertal pups spermatogenesis testicular testis timepoint tracers ultra uncompromised zo1
Tagcloud (Intersection) ?