LNX2 and NMD3

Number of citations of the paper that reports this interaction (PubMedID 29892012)
71

Data Source:
BioGRID (two hybrid)

		LNX2	NMD3
Description		ligand of numb-protein X 2	NMD3 ribosome export adaptor
Image
GO Annotations	Cellular Component	Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	RNA Binding Protein-macromolecule Adaptor Activity Ribosomal Large Subunit Binding
	Biological Process	Nervous System Development Neuron Differentiation Neural Precursor Cell Proliferation	Ribosomal Large Subunit Export From Nucleus Protein Transport Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Localization To Nucleolus
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 27863252 32888494) Night sleep phenotypes ( 27126917) Platelet distribution width ( 27863252 32888494) Response to cytadine analogues (cytosine arabinoside) ( 24483146)	Chronotype ( 30696823) Interleukin-10 levels ( 22205395) Morning person ( 30696823) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		90 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MECOM MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	4 interacting genes: CSNK2A1 LNX2 XPO1 YTHDF3
Entrez ID		222484	51068
HPRD ID		10042	13026
Ensembl ID		ENSG00000139517	ENSG00000169251
Uniprot IDs		Q8N448	C9JA08 Q96D46
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22 7QCT	6LQM 6LSR 6LU8
Enriched GO Terms of Interacting Partners?		Nucleoplasm Phosphotyrosine Residue Binding Post-translational Protein Modification Nucleus Protein Modification By Small Protein Conjugation Ubiquitin Conjugating Enzyme Activity Cytosol Ubiquitin-protein Transferase Activity Cellular Response To Nitric Oxide Cellular Response To Reactive Nitrogen Species Nuclear Speck Protein Ubiquitination Identical Protein Binding Response To Nitric Oxide Transferase Activity Cytoplasm	Regulation Of Translational Initiation Protein Localization To Organelle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Aggrephagy Organelle Assembly Annulate Lamellae Response To Triglyceride Cellular Response To Triglyceride Tooth Eruption Articular Cartilage Development Growth Plate Cartilage Chondrocyte Differentiation Negative Regulation Of Non-canonical Wnt Signaling Pathway Bone Mineralization Involved In Bone Maturation Response To Inositol Cartilage Homeostasis Receptor Localization To Non-motile Cilium Protein Stabilization Cellular Response To Salt Ribosomal Small Subunit Export From Nucleus Ribosomal Large Subunit Export From Nucleus Odontoblast Differentiation Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Protein Localization To Ciliary Membrane Wnt Signaling Pathway Membraneless Organelle Assembly Double-strand Break Repair Via Classical Nonhomologous End Joining Intracellular Transport Ribosomal Subunit Export From Nucleus Protein Localization To Non-motile Cilium Growth Plate Cartilage Development 9+0 Non-motile Cilium Osteoblast Proliferation Regulation Of Wnt Signaling Pathway Nuclear Export Signal Receptor Activity N6-methyladenosine-containing RNA Reader Activity Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Aggrephagy Protein Targeting To Vacuole Involved In Autophagy Regulation Of Protein Catabolic Process Regulation Of Protein Stability Negative Regulation Of Signal Transduction MRNA Methylguanosine-cap Decapping Regulation Of Proteolysis Intraciliary Anterograde Transport Regulation Of Trophoblast Cell Migration Intraciliary Transport Particle B
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?