LNX2 and PDZRN4

Number of citations of the paper that reports this interaction (PMID 22889411)
1

Data Source:
BioGRID (two hybrid)

		LNX2	PDZRN4
Gene Name		ligand of numb-protein X 2	PDZ domain containing ring finger 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Protein Binding Zinc Ion Binding PDZ Domain Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding
	Biological Process	Protein Homooligomerization	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Large B-cell lymphoma ( 21471979)	Multiple sclerosis ( 19010793) Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		17 interactors: CBX4 CXADR HOXA1 IGSF5 LNX1 MDGA1 NUMB PDZRN3 PDZRN4 PKDREJ RLIM RNF138 SHISA2 UBE2I UBE2T UBE2Z USP2	2 interactors: LNX1 LNX2
Entrez ID		222484	29951
HPRD ID		10042	15116
Ensembl ID		ENSG00000139517	ENSG00000165966
Uniprot IDs		Q8N448	B4DGD1 Q6ZMN7
PDB IDs		2VWR
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Sumoylation Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Optokinetic Behavior Abducens Nerve Formation Random Inactivation Of X Chromosome Positive Regulation Of SUMO Transferase Activity Protein Catabolic Process Facial Nucleus Development Positive Regulation Of Polarized Epithelial Cell Differentiation Protein Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere 4 Development Semicircular Canal Formation Cellular Macromolecule Catabolic Process Rhombomere 3 Development Rhombomere 5 Development Neuroblast Division In Subventricular Zone Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination AV Node Cell To Bundle Of His Cell Communication	Protein Homooligomerization Protein Oligomerization Protein Complex Assembly Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Component Assembly
Tagcloud ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt	5k3 alpl armitage beadchip bovinesnp50 bull capn1 catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36
Tagcloud (Difference) ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt	5k3 alpl armitage beadchip bovinesnp50 bull capn1 catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36
Tagcloud (Intersection) ?