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UBE2T and MARCH5
Number of citations of the paper that reports this interaction (PMID
19549727
)
40
Data Source:
BioGRID
(two hybrid)
UBE2T
MARCH5
Gene Name
ubiquitin-conjugating enzyme E2T
membrane-associated ring finger (C3HC4) 5
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
GTPase Binding
Biological Process
DNA Repair
Protein Monoubiquitination
Cellular Response To DNA Damage Stimulus
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Protein Polyubiquitination
Protein Autoubiquitination
Protein Localization To Mitochondrion
Regulation Of Mitochondrial Fission
Positive Regulation Of Mitochondrial Fission
Negative Regulation Of Cell Aging
Pathways
Fanconi Anemia pathway
Drugs
Diseases
GWAS
Breast cancer (
23535733
)
Protein-Protein Interactions
14 interactors:
AMFR
ARIH2
BRCA1
FANCL
LNX2
MARCH5
MGRN1
PCGF2
RNF128
RNF144B
RNF4
TRIM27
UBA1
UBA6
17 interactors:
AKTIP
FATE1
FIS1
MAP1B
MFN2
SOD1
TANK
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E3
UBE2I
UBE2N
UBE2T
UBE2W
UTRN
Entrez ID
29089
54708
HPRD ID
13704
07909
Ensembl ID
ENSG00000077152
ENSG00000198060
Uniprot IDs
Q9NPD8
B4DGV8
Q9NX47
PDB IDs
1YH2
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Protein K63-linked Ubiquitination
Protein Autoubiquitination
Cellular Macromolecule Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Protein K6-linked Ubiquitination
Proteolysis
Cellular Metabolic Process
Protein K48-linked Ubiquitination
Androgen Receptor Signaling Pathway
Protein Monoubiquitination
Catabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Intracellular Steroid Hormone Receptor Signaling Pathway
Cellular Response To Stress
Regulation Of Kinetochore Assembly
Negative Regulation Of Interleukin-2 Secretion
Positive Regulation Of Histone H3-K9 Acetylation
Positive Regulation Of Organelle Organization
Regulation Of Organelle Organization
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Regulation Of Centromere Complex Assembly
Protein Oligomerization
Regulation Of Cytoskeleton Organization
Cellular Response To Indole-3-methanol
Regulation Of Microtubule Cytoskeleton Organization
Negative Regulation Of Centriole Replication
Negative Regulation Of Calcium Ion Import
Regulation Of Cytokine Production
Dosage Compensation By Inactivation Of X Chromosome
Regulation Of Microtubule-based Process
Negative Regulation Of CAMP-mediated Signaling
Interferon-gamma Secretion
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Histone H3-K9 Methylation
Dosage Compensation
Regulation Of Histone H3-K9 Acetylation
Metabolic Process
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein K11-linked Ubiquitination
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor Signaling Pathway
Protein Monoubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Innate Immune Response
Regulation Of Innate Immune Response
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Catabolic Process
Proteasomal Protein Catabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Macromolecule Catabolic Process
Protein K63-linked Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Cellular Protein Modification Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Transferase Activity
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Stress
Proteolysis
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Positive Regulation Of Immune Response
Cellular Response To Oxygen Levels
Positive Regulation Of Cellular Protein Metabolic Process
Mitochondrial Fusion
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Ubiquitination
Cellular Protein Metabolic Process
Response To Stress
Regulation Of Immune System Process
Innate Immune Response
Regulation Of Immune Response
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