LNX2 and PDZRN3

Number of citations of the paper that reports this interaction (PMID 22889411)
1

Data Source:
BioGRID (two hybrid)

		LNX2	PDZRN3
Gene Name		ligand of numb-protein X 2	PDZ domain containing ring finger 3
Image
Gene Ontology Annotations	Cellular Component		Neuromuscular Junction
	Molecular Function	Protein Binding Zinc Ion Binding PDZ Domain Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Protein Homooligomerization	Neuromuscular Junction Development Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Large B-cell lymphoma ( 21471979)	Dialysis-related mortality ( 21546767)
Protein-Protein Interactions		17 interactors: CBX4 CXADR HOXA1 IGSF5 LNX1 MDGA1 NUMB PDZRN3 PDZRN4 PKDREJ RLIM RNF138 SHISA2 UBE2I UBE2T UBE2Z USP2	5 interactors: BMPR2 EFNB2 LNX1 LNX2 UBE2D2
Entrez ID		222484	23024
HPRD ID		10042	15115
Ensembl ID		ENSG00000139517	ENSG00000121440
Uniprot IDs		Q8N448	B7ZAG0 F5H8I9 Q9UPQ7
PDB IDs		2VWR	1UHP 1WH1
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Sumoylation Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Optokinetic Behavior Abducens Nerve Formation Random Inactivation Of X Chromosome Positive Regulation Of SUMO Transferase Activity Protein Catabolic Process Facial Nucleus Development Positive Regulation Of Polarized Epithelial Cell Differentiation Protein Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere 4 Development Semicircular Canal Formation Cellular Macromolecule Catabolic Process Rhombomere 3 Development Rhombomere 5 Development Neuroblast Division In Subventricular Zone Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination AV Node Cell To Bundle Of His Cell Communication	Lymph Vessel Development Regulation Of Chemotaxis Regulation Of Lung Blood Pressure Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of Vasoconstriction Regulation Of Behavior Protein Homooligomerization Regulation Of Epithelial Cell Proliferation Positive Regulation Of Axon Extension Involved In Axon Guidance Lymphatic Endothelial Cell Differentiation
Tagcloud ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Difference) ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Intersection) ?