LNX2 and PKDREJ

Number of citations of the paper that reports this interaction (PMID 22889411)
1

Data Source:
BioGRID (two hybrid)

		LNX2	PKDREJ
Gene Name		ligand of numb-protein X 2	polycystin (PKD) family receptor for egg jelly
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Zinc Ion Binding PDZ Domain Binding	Calcium Channel Activity Calcium Ion Binding
	Biological Process	Protein Homooligomerization	Acrosome Reaction Detection Of Mechanical Stimulus Regulation Of Acrosome Reaction Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Large B-cell lymphoma ( 21471979)
Protein-Protein Interactions		17 interactors: CBX4 CXADR HOXA1 IGSF5 LNX1 MDGA1 NUMB PDZRN3 PDZRN4 PKDREJ RLIM RNF138 SHISA2 UBE2I UBE2T UBE2Z USP2	2 interactors: LNX1 LNX2
Entrez ID		222484	10343
HPRD ID		10042	05239
Ensembl ID		ENSG00000139517	ENSG00000130943
Uniprot IDs		Q8N448	Q9NTG1
PDB IDs		2VWR
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Sumoylation Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Optokinetic Behavior Abducens Nerve Formation Random Inactivation Of X Chromosome Positive Regulation Of SUMO Transferase Activity Protein Catabolic Process Facial Nucleus Development Positive Regulation Of Polarized Epithelial Cell Differentiation Protein Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere 4 Development Semicircular Canal Formation Cellular Macromolecule Catabolic Process Rhombomere 3 Development Rhombomere 5 Development Neuroblast Division In Subventricular Zone Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination AV Node Cell To Bundle Of His Cell Communication	Protein Homooligomerization Protein Oligomerization Protein Complex Assembly Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Component Assembly
Tagcloud ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt	accelerated acrosome advantages competition constitute copulatory cricetidae cricetids divergence episodes evolution evolutionary fertilization influencing mass muridae participates primates proxy reproductive rodents selection sexual situations sperm steps testes testis undergo
Tagcloud (Difference) ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt	accelerated acrosome advantages competition constitute copulatory cricetidae cricetids divergence episodes evolution evolutionary fertilization influencing mass muridae participates primates proxy reproductive rodents selection sexual situations sperm steps testes testis undergo
Tagcloud (Intersection) ?