EPOR and IRS2

  • Number of citations of the paper that reports this interaction (PMID 9334184)
  • 10
  • Data Source:
  • HPRD (in vivo)

EPOR

IRS2

Gene Name erythropoietin receptor insulin receptor substrate 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 36 interactors: ATXN2L CBL CISH CRKL CSF2RB EPO GAB1 GAB2 GNAI1 GNB2L1 GRAP GRB2 INPP5D IRS2 JAK2 KIT KITLG KLK3 LYN MAPK1 MAPK3 MST1R PIK3R1 PLCG1 PLCG2 PTPN11 PTPN6 SH2B2 SHC1 SOCS2 SOCS3 STAT5A STAT5B SYK SYP VAV1 38 interactors: ATP2A1 ATP2A2 BCL2L1 CRK EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 MPL NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 PTPN6 PTPRF RPTOR SHC1 SIRT1 SOCS1 SOCS3 SOCS6 SOCS7 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ
Entrez ID 2057 8660
HPRD ID 00587 02878
Ensembl ID ENSG00000187266 ENSG00000185950
Uniprot IDs P19235 Q9P084 Q9Y4H2
PDB IDs 1CN4 1EBA 1EBP 1EER 1ERN 2JIX 3FQW 3FQX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actual  agonist  angstrom  antagonist  apart  configuration  crystal  dimer  efficiency  erythropoietin  far  formed  hematopoietic  homodimerization  insights  interact  ligands  mimetic  organization  peptide  permit  plasticity  preformed  recognition  resolution  spanning  thought  unliganded 
aacr  adaptive  adaptor  compensatory  conversely  cotargeting  dampen  dasatinib  ddr2  driven  emerged  gab1  harboring  igf1r  implicating  library  met  option  overlaying  panel  phosphoproteomics  py  rationale  res  rescued  rtk  scc  synergistic  weakly 
Tagcloud (Difference) ?
actual  agonist  angstrom  antagonist  apart  configuration  crystal  dimer  efficiency  erythropoietin  far  formed  hematopoietic  homodimerization  insights  interact  ligands  mimetic  organization  peptide  permit  plasticity  preformed  recognition  resolution  spanning  thought  unliganded 
aacr  adaptive  adaptor  compensatory  conversely  cotargeting  dampen  dasatinib  ddr2  driven  emerged  gab1  harboring  igf1r  implicating  library  met  option  overlaying  panel  phosphoproteomics  py  rationale  res  rescued  rtk  scc  synergistic  weakly 
Tagcloud (Intersection) ?