EPOR and SH2B2

  • Number of citations of the paper that reports this interaction (PMID 10374881)
  • 17
  • Data Source:
  • BioGRID (pull down)
  • HPRD (in vivo, in vitro)

EPOR

SH2B2

Gene Name erythropoietin receptor SH2B adaptor protein 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 36 interactors: ATXN2L CBL CISH CRKL CSF2RB EPO GAB1 GAB2 GNAI1 GNB2L1 GRAP GRB2 INPP5D IRS2 JAK2 KIT KITLG KLK3 LYN MAPK1 MAPK3 MST1R PIK3R1 PLCG1 PLCG2 PTPN11 PTPN6 SH2B2 SHC1 SOCS2 SOCS3 STAT5A STAT5B SYK SYP VAV1 21 interactors: AKT1 ASB6 BTK CBL EPOR ERBB2 FYN GRB2 INSR JAK1 JAK2 JAK3 KIT LYN NTRK1 NTRK2 PDLIM7 SH2B1 SHC1 SORBS1 SYK
Entrez ID 2057 10603
HPRD ID 00587 16097
Ensembl ID ENSG00000187266
Uniprot IDs P19235 O14492
PDB IDs 1CN4 1EBA 1EBP 1EER 1ERN 2JIX 1Q2H
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actual  agonist  angstrom  antagonist  apart  configuration  crystal  dimer  efficiency  erythropoietin  far  formed  hematopoietic  homodimerization  insights  interact  ligands  mimetic  organization  peptide  permit  plasticity  preformed  recognition  resolution  spanning  thought  unliganded 
accordingly  adaptor  aps  assembling  called  counteract  dephosphorylation  dimerization  dimers  hetero  homo  hyperphagia  insects  irs1  irs2  leptin  obesity  protecting  protects  psm  sh2b1  sh2b1beta  sh2b3  transgenes  trka  tyrosyl 
Tagcloud (Difference) ?
actual  agonist  angstrom  antagonist  apart  configuration  crystal  dimer  efficiency  erythropoietin  far  formed  hematopoietic  homodimerization  insights  interact  ligands  mimetic  organization  peptide  permit  plasticity  preformed  recognition  resolution  spanning  thought  unliganded 
accordingly  adaptor  aps  assembling  called  counteract  dephosphorylation  dimerization  dimers  hetero  homo  hyperphagia  insects  irs1  irs2  leptin  obesity  protecting  protects  psm  sh2b1  sh2b1beta  sh2b3  transgenes  trka  tyrosyl 
Tagcloud (Intersection) ?