EPOR and ATXN2L

Number of citations of the paper that reports this interaction (PMID 11784712)
2

Data Source:
HPRD (in vivo)

		EPOR	ATXN2L
Gene Name		erythropoietin receptor	ataxin 2-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Integral Component Of Plasma Membrane	Cytoplasm Cytoplasmic Stress Granule Membrane Nuclear Speck
	Molecular Function	Erythropoietin Receptor Activity Protein Binding Identical Protein Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Signal Transduction Brain Development Heart Development Erythropoietin-mediated Signaling Pathway Decidualization	Regulation Of Cytoplasmic MRNA Processing Body Assembly Stress Granule Assembly
Pathways
Drugs		Darbepoetin alfa Epoetin alfa 3,5 DIBROMOTYROSINE Peginesatide
Diseases
GWAS			Body mass index ( 20935630) Educational attainment ( 23722424)
Protein-Protein Interactions		36 interactors: ATXN2L CBL CISH CRKL CSF2RB EPO GAB1 GAB2 GNAI1 GNB2L1 GRAP GRB2 INPP5D IRS2 JAK2 KIT KITLG KLK3 LYN MAPK1 MAPK3 MST1R PIK3R1 PLCG1 PLCG2 PTPN11 PTPN6 SH2B2 SHC1 SOCS2 SOCS3 STAT5A STAT5B SYK SYP VAV1	4 interactors: ATXN1 EPOR HADHA MPL
Entrez ID		2057	11273
HPRD ID		00587	06394
Ensembl ID		ENSG00000187266	ENSG00000168488
Uniprot IDs		P19235	H3BUF6 Q8WWM7
PDB IDs		1CN4 1EBA 1EBP 1EER 1ERN 2JIX
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Response To Growth Hormone Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Response To Organic Substance Immune Response-regulating Signaling Pathway Fc-epsilon Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Intracellular Signal Transduction Cellular Response To Peptide Regulation Of Kinase Activity Fc Receptor Signaling Pathway Response To Peptide Hormone Regulation Of Body Fluid Levels JAK-STAT Cascade Response To Peptide Cellular Response To Organic Substance Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Blood Coagulation Regulation Of Immune System Process Hemostasis Innate Immune Response Defense Response Cellular Response To Hormone Stimulus Cellular Response To Organonitrogen Compound Regulation Of Signaling Immune System Process Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Regulation Of Protein Kinase Activity ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Phosphorylation Response To Hormone Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Response To Wounding Wound Healing Neurotrophin TRK Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Immune Response Neurotrophin Signaling Pathway Regulation Of Intracellular Signal Transduction Signaling Cell Communication See more	Erythropoietin-mediated Signaling Pathway Cellular Response To Erythropoietin Cardiolipin Acyl-chain Remodeling Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Tagcloud ?		actual agonist angstrom antagonist apart configuration crystal dimer efficiency erythropoietin far formed hematopoietic homodimerization insights interact ligands mimetic organization peptide permit plasticity preformed recognition resolution spanning thought unliganded
Tagcloud (Difference) ?		actual agonist angstrom antagonist apart configuration crystal dimer efficiency erythropoietin far formed hematopoietic homodimerization insights interact ligands mimetic organization peptide permit plasticity preformed recognition resolution spanning thought unliganded
Tagcloud (Intersection) ?