TSPYL2 and ZNF280C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSPYL2	ZNF280C
Description		TSPY like 2	zinc finger protein 280C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm	Nucleus
	Molecular Function	RDNA Binding Chromatin Binding Protein Binding Histone Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Chromatin Organization Nucleosome Assembly Negative Regulation Of DNA Replication Regulation Of Signal Transduction Negative Regulation Of Cell Growth Negative Regulation Of Cell Cycle Regulation Of Protein Kinase Activity	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS			Height ( 31562340) Reticulocyte count ( 32888494)
Interacting Genes		51 interacting genes: ABT1 AEBP2 APTX CASK CCNB1 CDK1 CDK2 CDK4 CEP19 COIL CREBBP CSNK2A1 DYRK1A EEF1A1 EZH2 GFI1B H2BC15 H3C1 HMGXB4 INO80B KDM6A KDM6B KMT5B LMO2 LNX1 MCRS1 NOL12 NOP53 PHF19 RBM15 RNF151 RPS25 SIRT6 SNIP1 TBC1D26 TMA16 TNNT1 TSPYL1 XAGE1A XAGE1B YAP1 ZBTB24 ZBTB48 ZFP1 ZNF280C ZNF286A ZNF329 ZNF524 ZNF687 ZNF775 ZNF835	6 interacting genes: CBX1 CBX5 GOLGA2 HOMEZ KRTAP10-6 TSPYL2
Entrez ID		64061	55609
HPRD ID		06713	06526
Ensembl ID		ENSG00000184205	ENSG00000056277
Uniprot IDs		Q9H2G4	Q8ND82
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Chromatin Organization Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Regulation Of Macromolecule Metabolic Process Nucleolus Regulation Of Primary Metabolic Process Regulation Of Metabolic Process DNA Repair RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA Metabolic Process Chromatin Binding Zinc Ion Binding DNA Damage Response G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Chromatin DNA Binding Transcription Regulator Complex Cyclin B1-CDK1 Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process ESC/E(Z) Complex Positive Regulation Of Chromosome Organization Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of DNA Metabolic Process Cyclin-dependent Protein Kinase Activity Regulation Of Cell Cycle G2/M Phase Transition Metal Ion Binding Cellular Response To Stress Telomere Organization Positive Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Histone H3K27me2/H3K27me3 Demethylase Activity Negative Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of DNA Repair Protein Localization To Site Of Double-strand Break Regulation Of DNA Repair Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Cardiac Muscle Cell Proliferation Cyclin-dependent Protein Serine/threonine Kinase Activity	Chromocenter Pericentric Heterochromatin Site Of DNA Damage Heterochromatin Chromatin Binding Positive Regulation Of Protein Glycosylation Chromatin Remodeling Heterochromatin Formation Negative Regulation Of Gene Expression, Epigenetic Chromosome, Centromeric Region Chromosome, Telomeric Region Golgi Disassembly Chromatin Organization Regulation Of Protein Glycosylation RDNA Binding Male Pronucleus Nucleolus Golgi Cis Cisterna Golgi Ribbon Formation Importin-alpha Family Protein Binding Female Pronucleus Epigenetic Regulation Of Gene Expression Chromatin Asymmetric Cell Division Meiotic Spindle Assembly Histone Methyltransferase Binding Positive Regulation Of Glycoprotein Biosynthetic Process Histone H3K9me2/3 Reader Activity
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