SH3D19 and SH3GL1

Number of citations of the paper that reports this interaction (PubMedID 14551139)
0

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SH3D19	SH3GL1
Description		SH3 domain containing 19	SH3 domain containing GRB2 like 1, endophilin A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane	Podosome Cytoplasm Endosome Cytosol Membrane Early Endosome Membrane Cell Projection Anchoring Junction Presynapse Glutamatergic Synapse
	Molecular Function	Protein Binding Proline-rich Region Binding	Protein Binding Lipid Binding Identical Protein Binding Cadherin Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Morphogenesis Positive Regulation Of Membrane Protein Ectodomain Proteolysis	Endocytosis Signal Transduction Central Nervous System Development
Pathways		Golgi Associated Vesicle Biogenesis	EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Hematocrit ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		13 interacting genes: ADAM10 ADAM12 ADAM15 ADAM17 ADAM9 CDC42 GRB2 SH3GL1 SH3GL3 SH3RF1 SH3YL1 SOS2 SYNJ1	35 interacting genes: ARHGAP1 ARHGAP8 AXIN1 B3GAT1 CCDC50 CMTM5 CREBBP DNM1 DNM1L DPPA4 DPYSL4 EEIG1 FBXO32 GPKOW ITCH ITSN2 MAL2 MTA1 NUTM2F PDCD6IP PML PRB3 PSMB1 PTPRO RHEX SCAMP5 SEPTIN8 SH2D4A SH3D19 SH3GL3 SOCS1 SPG21 SYNJ1 VPS37C YWHAZ
Entrez ID		152503	6455
HPRD ID		16364	03462
Ensembl ID		ENSG00000109686	ENSG00000141985
Uniprot IDs		A0A0U1RQE4 A0A494C1M0 Q5HYK7	Q6FGM0 Q99961
PDB IDs
Enriched GO Terms of Interacting Partners?		SH3 Domain Binding Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Metalloendopeptidase Activity Metallopeptidase Activity Amyloid Precursor Protein Catabolic Process Membrane Protein Ectodomain Proteolysis Amyloid Precursor Protein Metabolic Process Integrin-mediated Signaling Pathway Membrane Protein Proteolysis Integrin Binding Regulation Of Cellular Component Organization Peptidase Activity Endocytosis Metallodipeptidase Activity Monocyte Activation Positive Regulation Of T Cell Chemotaxis Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Hydrolase Activity Regulation Of T Cell Chemotaxis Import Into Cell Positive Regulation Of Lymphocyte Chemotaxis Signal Transduction Regulation Of Lymphocyte Chemotaxis Regulation Of Cell Growth Immune System Process Positive Regulation Of Cell Growth Regulation Of Cell Adhesion Focal Adhesion Cell Adhesion Mediated By Integrin Cell Surface Receptor Signaling Pathway Intracellular Signaling Cassette Protein Processing Positive Regulation Of T Cell Migration Vesicle Membrane Cell-cell Junction Signaling Receptor Ligand Precursor Processing Positive Regulation Of Lymphocyte Migration Postsynapse Organization Regulation Of Cell Migration Regulation Of Cell Motility Leukocyte Activation Positive Regulation Of Cell Migration Regulation Of T Cell Migration Glutamatergic Synapse Extracellular Matrix Disassembly Presynapse Constitutive Protein Ectodomain Proteolysis Positive Regulation Of Cell Motility Adherens Junction Organization Guanyl-nucleotide Exchange Factor Adaptor Activity	Negative Regulation Of Endocytic Recycling Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cytoplasm Membrane Fission
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