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SH3D19 and SOS2
Number of citations of the paper that reports this interaction (PMID
14551139
)
5
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
SH3D19
SOS2
Gene Name
SH3 domain containing 19
son of sevenless homolog 2 (Drosophila)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Cytosol
Molecular Function
Protein Binding
Proline-rich Region Binding
DNA Binding
Rho Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Protein Heterodimerization Activity
Biological Process
Post-Golgi Vesicle-mediated Transport
Cytoskeleton Organization
Regulation Of Cell Morphogenesis
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Membrane Organization
Small GTPase Mediated Signal Transduction
Axon Guidance
Positive Regulation Of Rho GTPase Activity
Positive Regulation Of Apoptotic Process
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Small GTPase Mediated Signal Transduction
Apoptotic Signaling Pathway
Pathways
Golgi Associated Vesicle Biogenesis
trans-Golgi Network Vesicle Budding
Clathrin derived vesicle budding
Signaling by GPCR
Signalling by NGF
Axon guidance
Cell death signalling via NRAGE, NRIF and NADE
p75 NTR receptor-mediated signalling
Rho GTPase cycle
GPCR downstream signaling
Activation of Rac
NRAGE signals death through JNK
Signaling by Rho GTPases
G alpha (12/13) signalling events
Signaling by Robo receptor
Drugs
Diseases
GWAS
Protein-Protein Interactions
11 interactors:
ADAM10
ADAM12
ADAM15
ADAM17
ADAM9
CDC42
GRB2
SH3GL1
SH3GL3
SH3YL1
SOS2
16 interactors:
ABI1
ABL1
BIN1
CD2AP
CRKL
EGFR
GRAP2
GRB2
HRAS
ITSN2
PACSIN3
PLCG1
SH3D19
SHC1
SNX18
SNX9
Entrez ID
152503
6655
HPRD ID
16364
03149
Ensembl ID
ENSG00000109686
ENSG00000100485
Uniprot IDs
Q5HYK7
B7ZKT6
Q07890
PDB IDs
Enriched GO Terms of Interacting Partners
?
PMA-inducible Membrane Protein Ectodomain Proteolysis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Collagen Catabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Collagen Metabolic Process
Membrane Protein Ectodomain Proteolysis
Multicellular Organismal Macromolecule Metabolic Process
Multicellular Organismal Metabolic Process
Extracellular Matrix Disassembly
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Membrane Protein Proteolysis
Anatomical Structure Development
Signal Transduction
Developmental Process
Monocyte Activation
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Cell Adhesion
Signaling
Regulation Of Cellular Component Organization
Cell Communication
System Development
Regulation Of ERBB Signaling Pathway
Positive Regulation Of T Cell Chemotaxis
Cell Morphogenesis Involved In Differentiation
Cell Surface Receptor Signaling Pathway
Cell Adhesion Mediated By Integrin
Extracellular Matrix Organization
Extracellular Structure Organization
Multicellular Organismal Development
Cell Differentiation
Axon Guidance
Integrin-mediated Signaling Pathway
Cellular Response To Stimulus
Anatomical Structure Morphogenesis
Positive Regulation Of T Cell Migration
Regulation Of T Cell Migration
Notch Receptor Processing
Cell Morphogenesis
Response To External Stimulus
Axonogenesis
Regulation Of Lymphocyte Migration
Axon Development
Cellular Response To Growth Factor Stimulus
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Cell Migration
Cell Adhesion
Neurotrophin TRK Receptor Signaling Pathway
Wound Healing
Chemotaxis
Endocytosis
Fc Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Vesicle-mediated Transport
Positive Regulation Of Metabolic Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of Catalytic Activity
Positive Regulation Of Cellular Protein Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Neurotrophin TRK Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of Protein Phosphorylation
Regulation Of Protein Kinase Activity
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Kinase Activity
Regulation Of Kinase Activity
Innate Immune Response
Positive Regulation Of Signal Transduction
Positive Regulation Of Phosphorylation
Regulation Of Catalytic Activity
Regulation Of Immune Response
Regulation Of Phosphorylation
Positive Regulation Of Transferase Activity
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Protein Modification Process
Positive Regulation Of Cellular Metabolic Process
Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of MAPK Cascade
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Activation Of MAPKK Activity
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Hydrolase Activity
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Regulation Of Protein Phosphorylation
Regulation Of Protein Metabolic Process
Ras Protein Signal Transduction
Positive Regulation Of MAPK Cascade
Lipid Tube Assembly
Cell Migration
Immune Response
Regulation Of Immune System Process
Activation Of Protein Kinase Activity
Defense Response
Immune Response-activating Cell Surface Receptor Signaling Pathway
Tagcloud
?
arnt
bio
biogrid
bmpr1b
crebl
dijkstra
ecm
etc
greedy
hsc
hscs
integrative
iterative
kegg
map2k1
nf1
pik3r3
ppp2r1a
prkca
searching
smad2
stellate
targetome
tfs
tranfac
transcriptome
transcriptomic
uncovered
underlie
Tagcloud (Difference)
?
arnt
bio
biogrid
bmpr1b
crebl
dijkstra
ecm
etc
greedy
hsc
hscs
integrative
iterative
kegg
map2k1
nf1
pik3r3
ppp2r1a
prkca
searching
smad2
stellate
targetome
tfs
tranfac
transcriptome
transcriptomic
uncovered
underlie
Tagcloud (Intersection)
?