SH3GL1 and B3GAT1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		SH3GL1	B3GAT1
Description		SH3 domain containing GRB2 like 1, endophilin A2	beta-1,3-glucuronyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Podosome Cytoplasm Endosome Cytosol Membrane Early Endosome Membrane Cell Projection Anchoring Junction Presynapse Glutamatergic Synapse	Golgi Membrane Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding Cadherin Binding	Protein Binding Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Transferase Activity Metal Ion Binding
	Biological Process	Endocytosis Signal Transduction Central Nervous System Development	Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process Protein Glycosylation Visual Learning Chondroitin Sulfate Proteoglycan Biosynthetic Process
Pathways		EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell	Glycosaminoglycan-protein linkage region biosynthesis
Drugs			D-tartaric acid Uridine-5'-Diphosphate
Diseases
GWAS		Appendicular lean mass ( 33097823) Hematocrit ( 32888494) Red cell distribution width ( 32888494)	Liver enzyme levels (alkaline phosphatase) ( 33972514) N-glycan levels ( 21908519) Neonatal white matter microstructure ( 33009551) Prostate cancer ( 29892016) Schizophrenia ( 33169155) Serum alkaline phosphatase levels ( 33547301) Verbal declarative memory ( 25648963)
Interacting Genes		35 interacting genes: ARHGAP1 ARHGAP8 AXIN1 B3GAT1 CCDC50 CMTM5 CREBBP DNM1 DNM1L DPPA4 DPYSL4 EEIG1 FBXO32 GPKOW ITCH ITSN2 MAL2 MTA1 NUTM2F PDCD6IP PML PRB3 PSMB1 PTPRO RHEX SCAMP5 SEPTIN8 SH2D4A SH3D19 SH3GL3 SOCS1 SPG21 SYNJ1 VPS37C YWHAZ	3 interacting genes: CMTM7 HLA-DMA SH3GL1
Entrez ID		6455	27087
HPRD ID		03462	06969
Ensembl ID		ENSG00000141985	ENSG00000109956
Uniprot IDs		Q6FGM0 Q99961	Q9P2W7
PDB IDs			1V82 1V83 1V84
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Endocytic Recycling Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cytoplasm Membrane Fission	B-1a B Cell Differentiation B-1 B Cell Differentiation
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