SH3D19

Description		SH3 domain containing 19
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Proline-rich Region Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Morphogenesis Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Interacting Genes		13 interacting genes: ADAM10 ADAM12 ADAM15 ADAM17 ADAM9 CDC42 GRB2 SH3GL1 SH3GL3 SH3RF1 SH3YL1 SOS2 SYNJ1
Entrez ID		152503
HPRD ID		16364
Ensembl ID		ENSG00000109686
Uniprot IDs		A0A0U1RQE4 A0A494C1M0 Q5HYK7
PDB IDs
Enriched GO Terms of Interacting Partners?		SH3 Domain Binding Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Metalloendopeptidase Activity Metallopeptidase Activity Amyloid Precursor Protein Catabolic Process Membrane Protein Ectodomain Proteolysis Amyloid Precursor Protein Metabolic Process Integrin-mediated Signaling Pathway Membrane Protein Proteolysis Integrin Binding Regulation Of Cellular Component Organization Peptidase Activity Endocytosis Metallodipeptidase Activity Monocyte Activation Positive Regulation Of T Cell Chemotaxis Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Hydrolase Activity Regulation Of T Cell Chemotaxis Import Into Cell Positive Regulation Of Lymphocyte Chemotaxis Signal Transduction Regulation Of Lymphocyte Chemotaxis Regulation Of Cell Growth Immune System Process Positive Regulation Of Cell Growth Regulation Of Cell Adhesion Focal Adhesion Cell Adhesion Mediated By Integrin Cell Surface Receptor Signaling Pathway Intracellular Signaling Cassette Protein Processing Positive Regulation Of T Cell Migration Vesicle Membrane Cell-cell Junction Signaling Receptor Ligand Precursor Processing Positive Regulation Of Lymphocyte Migration Postsynapse Organization Regulation Of Cell Migration Regulation Of Cell Motility Leukocyte Activation Positive Regulation Of Cell Migration Regulation Of T Cell Migration Glutamatergic Synapse Extracellular Matrix Disassembly Presynapse Constitutive Protein Ectodomain Proteolysis Positive Regulation Of Cell Motility Adherens Junction Organization Guanyl-nucleotide Exchange Factor Adaptor Activity
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