CXADR and EWSR1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		CXADR	EWSR1
Description		CXADR cell adhesion molecule	EWS RNA binding protein 1
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GO Annotations	Cellular Component	Acrosomal Vesicle Extracellular Region Extracellular Space Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction Intercalated Disc Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Cell Junction Filopodium Growth Cone Neuromuscular Junction Protein-containing Complex Neuron Projection Cell Body Membrane Raft Anchoring Junction	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cajal Body Membrane
	Molecular Function	Virus Receptor Activity Signaling Receptor Binding Integrin Binding Protein Binding Beta-catenin Binding PDZ Domain Binding Identical Protein Binding Cell Adhesion Molecule Binding Connexin Binding Cell Adhesive Protein Binding Involved In AV Node Cell-bundle Of His Cell Communication	Nucleic Acid Binding Transcription Coregulator Activity RNA Binding Protein Binding Calmodulin Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Mitochondrion Organization Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Heart Development Germ Cell Migration Epithelial Structure Maintenance Actin Cytoskeleton Organization Neutrophil Chemotaxis Homotypic Cell-cell Adhesion Cell-cell Junction Organization Gamma-delta T Cell Activation Symbiont Entry Into Host Cell Defense Response To Virus Cardiac Muscle Cell Development Transepithelial Transport AV Node Cell To Bundle Of His Cell Communication AV Node Cell-bundle Of His Cell Adhesion Involved In Cell Communication Regulation Of AV Node Cell Action Potential	Regulation Of DNA-templated Transcription
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall
Drugs
Diseases			Extraskeletal myxoid chondrosarcoma Myxoid liposarcoma Ewing's sarcoma Clear cell sarcoma of soft tissue
GWAS		Neutrophil count ( 32888494) Serum alkaline phosphatase levels ( 33547301)	Breast cancer ( 23535729) Pancreatic cancer ( 25086665) Platelet count ( 27863252) Platelet distribution width ( 32888494)
Interacting Genes		11 interacting genes: ANKRD46 EWSR1 FAM3C JAML LNX1 LNX2 MAL NCOA1 NCOR1 OGT VKORC1	164 interacting genes: ACTL6A AGT ANXA11 ARID1A ATN1 ATPAF2 ATXN3 BAD BARD1 BLZF1 BNIP3L BRME1 BTK C11orf16 CALM1 CCDC7 CCDC91 CD177 CDK12 CEACAM5 CEBPA CETP CFAP298 CFDP1 CHERP CNST CPSF6 CPSF7 CREBBP CUEDC2 CXADR DFFA DMRTB1 DNAJB3 DYNLL2 E2F8 ECD ELAVL3 ELAVL4 ELK1 EPAS1 ERCC5 FAM131C FASN FLI1 FXR2 GNPDA1 GPBP1L1 H2BC15 HBP1 HDAC3 HERPUD1 HLTF HMGA1 HMGN4 HNRNPUL1 HSPA2 IRF3 ITCH ITGB5 JUN KCNMB1 KEL KHDRBS2 KRR1 KXD1 LILRA3 MAGEA11 MAPK1IP1L MATK MDFI MNS1 MRPS18B MSC MTCP1 MTMR9 MVK MYL6 MYO1F MYOZ2 NBPF3 NDRG1 NDUFB1 NDUFV1 NINL NLE1 NONO NPPB NSUN4 NTNG2 OGT PCBP1 PDHX PEF1 PGLS PLSCR1 POLR2G POLR3A POU4F1 POU5F1 PRKCA PRMT1 PRR13 PRRC2A PRTFDC1 PRUNE2 PTK2B PTP4A2 RAB37 RAD23A RALYL RASL11B RBPMS RFX3 RHOXF2 RMND5B RNF183 RPL31 RPS15A SALL2 SCMH1 SEC24A SEC24D SELENOI SERP2 SF1 SF3B4 SLC1A1 SLC22A24 SMAD1 SMAD4 SMARCC1 SMARCC2 SNRPC SSBP2 SSBP3 SUPT4H1 SUV39H2 TAF1 TFG TMSB4Y TONSL TPGS2 TRAF1 TRAF2 TRAF3 TRIM37 TRIM5 TRPV5 TSPAN3 TULP2 USP7 VPS72 WBP4 WDR37 WWP1 WWP2 YWHAG YY1AP1 ZBTB1 ZDHHC3 ZNF165 ZNF184 ZNF383
Entrez ID		1525	2130
HPRD ID		11804	00592
Ensembl ID		ENSG00000154639	ENSG00000182944
Uniprot IDs		P78310	A0A0D9SFL3 Q01844
PDB IDs		1EAJ 1F5W 1JEW 1KAC 1P69 1P6A 1RSF 2J12 2J1K 2NPL 2W9L 2WBW 3J6L 3J6M 3J6N 3J6O 7DPZ 7DQ1 7VXZ 7VYK 7VYL 7VYM 7W14	2CPE
Enriched GO Terms of Interacting Partners?		Carbon Catabolite Regulation Of Transcription Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Glycolytic Process Cellular Response To Nutrient Granulocyte Differentiation MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Nuclear Receptor Binding Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Protein Localization To Lysosome Rhythmic Process MRNA Transcription Regulation Of Carbohydrate Catabolic Process Regulation Of Body Fluid Levels Regulation Of ATP Metabolic Process Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Labyrinthine Layer Morphogenesis Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Regulation Of Purine Nucleotide Metabolic Process PDZ Domain Binding Membrane Raft Polarization Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Protein Localization To Vacuole Protein O-acetylglucosaminyltransferase Activity Cellular Response To Thyroglobulin Triiodothyronine Positive Regulation Of Female Receptivity Protein Localization To Paranode Region Of Axon Nuclear Speck Organization Chromatin Organization Positive Regulation Of NK T Cell Differentiation Coagulation Blood Coagulation Hemostasis	Nucleoplasm Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Nucleus Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Chromatin Organization RNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process DNA-templated Transcription Transcription Regulator Complex Chromatin Remodeling MRNA Metabolic Process Brahma Complex NpBAF Complex RNA Metabolic Process Regulation Of Gene Expression Nucleic Acid Binding Chromatin Single-stranded DNA Binding Protein-containing Complex Negative Regulation Of DNA-templated Transcription Cardiac Conduction System Development Chromatin Binding Negative Regulation Of RNA Biosynthetic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Protein Binding MRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Stress Nucleosome Disassembly TORC1 Signaling Negative Regulation Of Macromolecule Biosynthetic Process
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