CXADR and ANKRD46

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CXADR	ANKRD46
Description		CXADR cell adhesion molecule	ankyrin repeat domain 46
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Extracellular Region Extracellular Space Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction Intercalated Disc Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Cell Junction Filopodium Growth Cone Neuromuscular Junction Protein-containing Complex Neuron Projection Cell Body Membrane Raft Anchoring Junction	Membrane
	Molecular Function	Virus Receptor Activity Signaling Receptor Binding Integrin Binding Protein Binding Beta-catenin Binding PDZ Domain Binding Identical Protein Binding Cell Adhesion Molecule Binding Connexin Binding Cell Adhesive Protein Binding Involved In AV Node Cell-bundle Of His Cell Communication	Protein Binding
	Biological Process	Mitochondrion Organization Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Heart Development Germ Cell Migration Epithelial Structure Maintenance Actin Cytoskeleton Organization Neutrophil Chemotaxis Homotypic Cell-cell Adhesion Cell-cell Junction Organization Gamma-delta T Cell Activation Symbiont Entry Into Host Cell Defense Response To Virus Cardiac Muscle Cell Development Transepithelial Transport AV Node Cell To Bundle Of His Cell Communication AV Node Cell-bundle Of His Cell Adhesion Involved In Cell Communication Regulation Of AV Node Cell Action Potential
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Neutrophil count ( 32888494) Serum alkaline phosphatase levels ( 33547301)	Atrioventricular conduction ( 21041692) Body mass index ( 26426971) Percentage gas trapping ( 26030696)
Interacting Genes		11 interacting genes: ANKRD46 EWSR1 FAM3C JAML LNX1 LNX2 MAL NCOA1 NCOR1 OGT VKORC1	63 interacting genes: AMIGO1 APH1A AQP6 ARL13B BIK BSCL2 C16orf54 CD22 CD46 CLDN20 CLDN7 CLEC4D CRB3 CREB3L1 CXADR CYB561 EBP EFNB1 EFNB2 ELOVL4 FAM174A FAM209A FFAR2 GOLM1 GPR152 GPR42 GPX8 HSD17B11 HSD17B13 IFNLR1 KASH5 KIR2DL3 LAMTOR5 LDLRAD1 LRRC25 MFF MMGT1 MUC1 NCAPH2 NSG2 PLPP4 PVR RELL2 RETREG3 SCN3B SECTM1 SHISA3 SLC10A6 SLC16A2 SLC18A1 SLC39A9 ST6GALNAC6 STX1A STX2 STX4 SUSD3 THAP4 TIMMDC1 TMEM248 TMEM31 TMEM45B TMEM79 TMPRSS2
Entrez ID		1525	157567
HPRD ID		11804	14103
Ensembl ID		ENSG00000154639	ENSG00000186106
Uniprot IDs		P78310	B3KT99 Q86W74
PDB IDs		1EAJ 1F5W 1JEW 1KAC 1P69 1P6A 1RSF 2J12 2J1K 2NPL 2W9L 2WBW 3J6L 3J6M 3J6N 3J6O 7DPZ 7DQ1 7VXZ 7VYK 7VYL 7VYM 7W14
Enriched GO Terms of Interacting Partners?		Carbon Catabolite Regulation Of Transcription Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Glycolytic Process Cellular Response To Nutrient Granulocyte Differentiation MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Nuclear Receptor Binding Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Protein Localization To Lysosome Rhythmic Process MRNA Transcription Regulation Of Carbohydrate Catabolic Process Regulation Of Body Fluid Levels Regulation Of ATP Metabolic Process Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Labyrinthine Layer Morphogenesis Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Regulation Of Purine Nucleotide Metabolic Process PDZ Domain Binding Membrane Raft Polarization Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Protein Localization To Vacuole Protein O-acetylglucosaminyltransferase Activity Cellular Response To Thyroglobulin Triiodothyronine Positive Regulation Of Female Receptivity Protein Localization To Paranode Region Of Axon Nuclear Speck Organization Chromatin Organization Positive Regulation Of NK T Cell Differentiation Coagulation Blood Coagulation Hemostasis	Membrane Protein Binding Plasma Membrane Steroid Dehydrogenase Activity
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