MGAT5B and OTX1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MGAT5B	OTX1
Gene Name		mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	orthodenticle homeobox 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane	Nucleus
	Molecular Function	Protein Binding Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Metal Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
	Biological Process	Protein N-linked Glycosylation	Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Diencephalon Morphogenesis
Pathways
Drugs
Diseases
GWAS		Cannabis use (initiation) ( 22823124) Cardiac repolarization ( 22683750)
Protein-Protein Interactions		21 interactors: C20orf195 CAMK2B CREB5 DMRT3 EIF4ENIF1 FAM83A HOXA1 KLHL38 KRTAP12-2 KRTAP19-5 KRTAP26-1 MDFI OTX1 PITX1 PLSCR1 PTGER3 RBPMS STK16 TRIP13 TXNDC5 VAC14	39 interactors: CHIC2 CHRD COMP GEMIN8P4 GRN KCNK16 KRT81 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE4A MDFI MGAT5B RBPMS RGS17 RGS20 SMARCC1 SPRY1 SPRY2 TLE4
Entrez ID		146664	5013
HPRD ID		14392	08964
Ensembl ID		ENSG00000167889	ENSG00000115507
Uniprot IDs		Q3V5L5	P32242
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Pattern Specification Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Acute-phase Response Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cellular Process Embryonic Morphogenesis Abducens Nerve Formation Optokinetic Behavior Inhibitory G-protein Coupled Receptor Phosphorylation Embryonic Organ Morphogenesis Acute Inflammatory Response Facial Nucleus Development Activation Of Meiosis Involved In Egg Activation Diencephalon Development Inner Ear Morphogenesis Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Rhombomere 4 Development Branchiomeric Skeletal Muscle Development Semicircular Canal Formation Rhombomere 3 Development Rhombomere 5 Development Activation Of Meiosis Fever Generation	Keratinization Keratinocyte Differentiation Epithelium Development Epidermis Development Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Tissue Development Epidermal Cell Differentiation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Skin Development Organ Development Developmental Process Negative Regulation Of Ras GTPase Activity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Anatomical Structure Development Branch Elongation Of An Epithelium Negative Regulation Of Signal Transduction Developmental Growth Involved In Morphogenesis Negative Regulation Of Signaling Negative Regulation Of GTPase Activity Axis Elongation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Establishment Of Mitotic Spindle Orientation Multicellular Organismal Development Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway System Development Spindle Localization BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Epithelial Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Ras Protein Signal Transduction Organ Morphogenesis Negative Regulation Of Small GTPase Mediated Signal Transduction Lung Morphogenesis Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Developmental Growth Regulation Of MAP Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Negative Regulation Of MAP Kinase Activity Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Organ Growth Regulation Of GTPase Activity Negative Regulation Of Cellular Response To Growth Factor Stimulus Establishment Of Cell Polarity
Tagcloud ?			17q21 2p15 allowing amplification antecedent bcl11a cdkn2a cgh commd1 diffuse disrupting dlbcl dndlbcl driver encompassing exclusively fl follicular lymphoma never nfkappabeta novo outline paired possessed rel tdlbcl transformation usp34
Tagcloud (Difference) ?			17q21 2p15 allowing amplification antecedent bcl11a cdkn2a cgh commd1 diffuse disrupting dlbcl dndlbcl driver encompassing exclusively fl follicular lymphoma never nfkappabeta novo outline paired possessed rel tdlbcl transformation usp34
Tagcloud (Intersection) ?