MGAT5B and IQCE

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MGAT5B	IQCE
Description		alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	IQ motif containing E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Plasma Membrane Cilium Membrane Cell Projection Ciliary Membrane
	Molecular Function	Protein Binding Transferase Activity Glycosyltransferase Activity Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Manganese Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation	Limb Morphogenesis
Pathways		DAG1 core M2 glycosylations	Activation of SMO
Drugs
Diseases
GWAS		Cannabis use (initiation) ( 22823124) Colorectal or endometrial cancer ( 26621817) Early cardiac repolarization ( 22683750) Nicotine dependence symptom count ( 25555482) Pulmonary emphysema ( 24383474) Refractive error ( 32231278) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)	Anxiety disorders ( 31906708) Food allergy (parent-of-origin effect) ( 29489655) Urate levels in lean individuals ( 25811787)
Interacting Genes		112 interacting genes: ABHD11 ADAMTSL4 ADRA2C ANAPC11 ANTKMT ATG9A ATP23 BMF C10orf55 C17orf50 C22orf39 CAMK2B CD46 CFAP68 CFTR CIMIP2B CREB5 CSN3 CTAG1A CTAG1B CXCL5 CYSRT1 DMRT3 EIF4E2 EIF4ENIF1 FAM83A FNDC11 FOXH1 GATA1 GLYCTK GNE HIGD2B HOXA1 HOXC8 HR HSD3B7 HUNK IGLL5 IQCE IVD KCTD17 KLHL38 KPRP KRT86 KRTAP1-1 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP22-1 KRTAP26-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-2 LASP1 LONRF1 MAGED1 MCCD1 MDFI MKRN3 MSX2 NHLRC4 OIP5 OTX1 PITX1 PLA2G10 PLSCR1 PTGER3 PTH1R PTPRZ1 R3HDM2 RBP3 RBPMS RHOXF2 RSKR RTN4R SLC16A5 SLC25A48 SMARCC1 SMUG1 SNRPC SPAG8 SSC4D STK16 SYNGAP1 TBX6 TEKT5 TENT5B TMEM42 TNS2 TRIM35 TRIM42 TRIP13 TSPAN4 TXNDC5 TYRO3 UBAP2 UNKL VAC14 ZIC1 ZNF20 ZNF414 ZNF581	18 interacting genes: CALM1 CALM2 CALM3 CARD9 CEP70 CRK GOLGA2 GPSM3 HNRNPF HOOK2 LZTS2 MGAT5B MTUS2 PSMA3 RPGRIP1 SPAG5 TRIM23 TRIM27
Entrez ID		146664	23288
HPRD ID		14392	11050
Ensembl ID		ENSG00000167889	ENSG00000106012
Uniprot IDs		Q3V5L5	A0A087WX19 A0A087WX45 B3KRY4 B4DDX4 B4DXN1 Q6IPM2
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Keratin Filament	Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Centrosome Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Detection Of Calcium Ion Spindle Pole Cytoskeleton Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calyx Of Held Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Calcium Channel Complex Calcineurin-mediated Signaling Presynaptic Cytosol Myelin Sheath Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Establishment Of Localization In Cell Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Sperm Midpiece Positive Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Microtubule Long-term Synaptic Potentiation Sarcomere Cell Cycle G2/M Phase Transition Negative Regulation Of Voltage-gated Calcium Channel Activity Vesicle Cytoplasm Neural Nucleus Development Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Negative Regulation Of Monoatomic Ion Transmembrane Transport Adenylate Cyclase Binding Voltage-gated Potassium Channel Complex Calcium-dependent Protein Binding
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