MGAT5B and KRTAP6-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MGAT5B	KRTAP6-2
Description		alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	keratin associated protein 6-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Cytosol Intermediate Filament
	Molecular Function	Protein Binding Transferase Activity Glycosyltransferase Activity Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Manganese Ion Binding Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation	Keratinization
Pathways		DAG1 core M2 glycosylations	Keratinization
Drugs
Diseases
GWAS		Cannabis use (initiation) ( 22823124) Colorectal or endometrial cancer ( 26621817) Early cardiac repolarization ( 22683750) Nicotine dependence symptom count ( 25555482) Pulmonary emphysema ( 24383474) Refractive error ( 32231278) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)
Interacting Genes		112 interacting genes: ABHD11 ADAMTSL4 ADRA2C ANAPC11 ANTKMT ATG9A ATP23 BMF C10orf55 C17orf50 C22orf39 CAMK2B CD46 CFAP68 CFTR CIMIP2B CREB5 CSN3 CTAG1A CTAG1B CXCL5 CYSRT1 DMRT3 EIF4E2 EIF4ENIF1 FAM83A FNDC11 FOXH1 GATA1 GLYCTK GNE HIGD2B HOXA1 HOXC8 HR HSD3B7 HUNK IGLL5 IQCE IVD KCTD17 KLHL38 KPRP KRT86 KRTAP1-1 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP22-1 KRTAP26-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-2 LASP1 LONRF1 MAGED1 MCCD1 MDFI MKRN3 MSX2 NHLRC4 OIP5 OTX1 PITX1 PLA2G10 PLSCR1 PTGER3 PTH1R PTPRZ1 R3HDM2 RBP3 RBPMS RHOXF2 RSKR RTN4R SLC16A5 SLC25A48 SMARCC1 SMUG1 SNRPC SPAG8 SSC4D STK16 SYNGAP1 TBX6 TEKT5 TENT5B TMEM42 TNS2 TRIM35 TRIM42 TRIP13 TSPAN4 TXNDC5 TYRO3 UBAP2 UNKL VAC14 ZIC1 ZNF20 ZNF414 ZNF581	186 interacting genes: ADAM12 ADAMTSL4 ANAPC11 ANKS1A ANXA11 APOBEC1 AQP1 ARID5A ATG9A ATN1 ATOSB ATPAF2 BEX2 BHLHE40 C10orf55 C1orf94 C6orf15 CAMK2A CAMK2B CASC3 CATSPER1 CCDC120 CCDC17 CCDC28A-AS1 CCER1 CCNK CELF5 CERCAM CERK CFP CHIC2 CIMIP1 CIMIP2B COL8A1 CREB5 CTRC CYSRT1 DAZAP2 DHRS1 DMRT3 ENKD1 ESR2 FAAP20 FAM168A FAM83A FOXD2 FOXD4L1 FOXD4L3 FOXP3 FRS3 GALT GATA3 GCM2 GLIS2 GLYCTK GNE GPS2 GRINA GRN GSTP1 HAPLN2 HELT HEY1 HEY2 HEYL HHEX HOXA1 HOXB9 HOXC8 HOXC9 HSF4 HYAL2 IGFN1 INCA1 INO80B ITGB4 KLHL38 KPRP KRT83 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP15-1 KRTAP19-5 KRTAP26-1 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP6-1 KRTAP6-3 LASP1 LCE2B LCE2D LCE5A LETM1 LGALS9C LRFN4 LRRC41 LYVE1 MEIS2 MGAT5B MKRN3 NAF1 NDUFA9 NEU4 NFKBID NID2 NPBWR2 NR1D2 NSD1 OLIG3 OTX1 OXER1 PATL1 PATZ1 PAX3 PDP1 PHLDA1 PITX1 PKD2 PLEKHN1 PLSCR4 POGZ POU5F2 PRR13 PRR3 PRR30 PRR35 RASD1 RBFOX2 RBPMS2 RERE RHOXF2 RNF38 ROR2 RTP5 RUNX1T1 RUSC1 SAMD7 SAXO4 SHARPIN SIAH3 SMAP2 SMARCC1 SMN1 SMN2 SMUG1 SNRPB SNRPC SPAG8 SPATA8 SPMIP9 TBX6 TCF7L2 TEKT3 TEKT4 TEKT5 TENT5B TENT5D TEPSIN TFAP2D TLE5 TLX2 TLX3 TNIP1 TOLLIP TPRX1 TRIP13 TSGA10IP TSPAN4 TSPYL6 VAC14 VENTX VGLL3 VPS37C YPEL3 ZBTB32 ZC3H10 ZIC1 ZNF414 ZNF503 ZNF581 ZNF683 ZNF843
Entrez ID		146664	337967
HPRD ID		14392	11219
Ensembl ID		ENSG00000167889	ENSG00000186930
Uniprot IDs		Q3V5L5	Q3LI66
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Keratin Filament	Protein Binding Chromatin DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Intermediate Filament Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Axonemal A Tubule Inner Sheath Negative Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleus Positive Regulation Of RNA Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Keratin Filament Keratinization Regulation Of Gene Expression Anterior/posterior Pattern Specification Regulation Of Primary Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Sperm Flagellum DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Corepressor Activity Positive Regulation Of Biosynthetic Process Umbilical Cord Morphogenesis Pattern Specification Process Identical Protein Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Cardiac Ventricle Morphogenesis Flagellated Sperm Motility Sperm Motility Myoblast Fate Commitment Positive Regulation Of Macromolecule Metabolic Process Hair Cycle Cilium-dependent Cell Motility
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