BMP1 and YLPM1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		BMP1	YLPM1
Gene Name		bone morphogenetic protein 1	YLP motif containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Golgi Apparatus Membrane-bounded Vesicle	Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Metalloendopeptidase Activity Cytokine Activity Calcium Ion Binding Growth Factor Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Poly(A) RNA Binding
	Biological Process	Skeletal System Development Cartilage Condensation Ossification Proteolysis Multicellular Organismal Development Extracellular Matrix Disassembly Cell Differentiation Extracellular Matrix Organization Lipoprotein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Cartilage Development	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Biological_process Regulation Of Telomere Maintenance
Pathways		Collagen formation Crosslinking of collagen fibrils Anchoring fibril formation Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		14 interactors: ADRA1A CHRD COL1A1 COL5A1 COL5A2 COL7A1 GEM HSPG2 LAMA3 LAMB3 LAMC2 TP53 TWSG1 YLPM1	11 interactors: APBB1 BMP1 CACNA1A CHGB GRB2 ITSN2 NONO PPP1CA PPP1CC PRMT1 PRPF40A
Entrez ID		649	56252
HPRD ID		00209	11688
Ensembl ID		ENSG00000168487	ENSG00000119596
Uniprot IDs		P13497	P49750 Q8NF45
PDB IDs		3EDG 3EDH
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Gastrulation Tissue Development Formation Of Primary Germ Layer Embryonic Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Hemidesmosome Assembly Collagen Catabolic Process Embryo Development Anatomical Structure Morphogenesis Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Anatomical Structure Development Ossification Negative Regulation Of Endodermal Cell Differentiation Epithelium Development Developmental Process Endodermal Cell Differentiation Cell Differentiation Cell-substrate Junction Assembly Multicellular Organismal Development Endoderm Formation Collagen Fibril Organization Epidermis Development Endoderm Development Collagen Biosynthetic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Adhesion Regulation Of Embryonic Development Negative Regulation Of Cell Differentiation Head Development Organ Development Negative Regulation Of Embryonic Development Regulation Of Cell Differentiation Organ Morphogenesis Cell Junction Assembly Regulation Of Gastrulation Cartilage Development Involved In Endochondral Bone Morphogenesis Skeletal System Development Endochondral Ossification Skin Development Negative Regulation Of BMP Signaling Pathway Response To External Stimulus Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Connective Tissue Development Negative Regulation Of Osteoblast Differentiation Cellular Response To Amino Acid Stimulus	Regulation Of Circadian Rhythm Energy Reserve Metabolic Process Response To Radiation Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Circadian Rhythm Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Energy Derivation By Oxidation Of Organic Compounds Rhythmic Process Neuron Projection Development Glycogen Metabolic Process Response To Light Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cerebellar Molecular Layer Development Negative Regulation Of Thymidylate Synthase Biosynthetic Process Neuron Development Response To External Stimulus Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Generation Of Precursor Metabolites And Energy Cell Division Regulation Of Signaling Triglyceride Metabolic Process Negative Regulation Of Signal Transduction Response To Abiotic Stimulus Neuron Differentiation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Vestibular Nucleus Development Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Projection Organization Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Signaling Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Transforming Growth Factor Beta Receptor Signaling Pathway Cell Cycle Gamma-aminobutyric Acid Secretion Response To Growth Factor Cellular Lipid Catabolic Process Anatomical Structure Morphogenesis Neuron Projection Morphogenesis Negative Regulation Of Megakaryocyte Differentiation Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Acetylcholine Secretion, Neurotransmission Regulation Of Apoptotic Process
Tagcloud ?		augment c1r c1s cub embryogenesis fli1a founding gata1 hbbe1 hematopoiesis hierarchy injecting maternally mesoderm morphants morphogenetic morpholino mount mpo myelomonocytic oligonucleotide plastin primitive pu scube scube1 uegf zebrafish
Tagcloud (Difference) ?		augment c1r c1s cub embryogenesis fli1a founding gata1 hbbe1 hematopoiesis hierarchy injecting maternally mesoderm morphants morphogenetic morpholino mount mpo myelomonocytic oligonucleotide plastin primitive pu scube scube1 uegf zebrafish
Tagcloud (Intersection) ?