ZC3H7A and WDR83

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		ZC3H7A	WDR83
Description		zinc finger CCCH-type containing 7A	WD repeat domain 83
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Spliceosomal Complex Cytoplasm Lysosome Endosome Membrane Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding MiRNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Post-transcriptional Regulation Of Gene Expression MiRNA Processing	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Response To Hypoxia Neural Tube Closure MRNA Processing RNA Splicing Response To Wounding Response To Lipopolysaccharide Regulation Of Canonical NF-kappaB Signal Transduction Placenta Blood Vessel Development Inflammatory Response To Wounding
Pathways			MAP2K and MAPK activation
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Metabolite levels ( 23823483) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) QT interval ( 19305408) Response to selenium supplementation (change in plasma selenium concentration) ( 33382417)
Interacting Genes		10 interacting genes: COL7A1 LARP4 MIR16-2 MIR29A MIR7-1 MIR92A2 MORF4L1 PAK1 STK3 WDR83	36 interacting genes: BAG2 BCAS2 BCL6 CRB3 CRK CRYAA EGLN3 EXOSC1 FAM124B FRS3 GNE GPKOW GTSE1 HNRNPH2 HOXA1 HSPB1 KCTD9 KDM1A KEAP1 LONRF1 LSM3 NOXA1 PARD6A PARD6B PCBP2 PRKAB2 RACK1 SAP30BP SF1 SRSF8 TLX3 TOE1 VAC14 WBP4 ZC3H7A ZNF76
Entrez ID		29066	84292
HPRD ID		11694	14730
Ensembl ID		ENSG00000122299	ENSG00000123154
Uniprot IDs		Q8IWR0	Q9BRX9
PDB IDs		2D9M
Enriched GO Terms of Interacting Partners?		RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Organ Growth	Nucleoplasm Nucleus Identical Protein Binding RNA Binding Nucleic Acid Binding Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Processing PAR Polarity Complex RNA Splicing, Via Transesterification Reactions RNA Splicing Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Binding Establishment Or Maintenance Of Apical/basal Cell Polarity MRNA Metabolic Process MRNA Processing Establishment Or Maintenance Of Cell Polarity RNA Metabolic Process MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Precatalytic Spliceosome
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