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LAMA1 and ITGA1
Number of citations of the paper that reports this interaction (PMID
9688542
)
19
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
LAMA1
ITGA1
Gene Name
laminin, alpha 1
integrin, alpha 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Proteinaceous Extracellular Matrix
Basement Membrane
Laminin-1 Complex
Laminin-3 Complex
Extracellular Space
Cell-cell Junction
Extracellular Matrix
Acrosomal Vesicle
Plasma Membrane
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Membrane
Integrin Alpha1-beta1 Complex
Neuron Projection
Perikaryon
Membrane Raft
Basal Part Of Cell
Extracellular Vesicular Exosome
Molecular Function
Receptor Binding
Extracellular Matrix Structural Constituent
Protein Binding
Glycosphingolipid Binding
Receptor Binding
Protein Binding
Collagen Binding
Protein Phosphatase Binding
Metal Ion Binding
Collagen Binding Involved In Cell-matrix Adhesion
Biological Process
Morphogenesis Of An Epithelial Sheet
Cell Adhesion
Cell Surface Receptor Signaling Pathway
Axon Guidance
Regulation Of Cell Adhesion
Extracellular Matrix Organization
Regulation Of Cell Migration
Establishment Of Epithelial Cell Apical/basal Polarity
Regulation Of Embryonic Development
Epithelial Tube Branching Involved In Lung Morphogenesis
Branching Involved In Salivary Gland Morphogenesis
Retinal Blood Vessel Morphogenesis
Activation Of MAPK Activity
Muscle Contraction
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Axon Guidance
Blood Coagulation
Negative Regulation Of Cell Proliferation
Extracellular Matrix Organization
Neutrophil Chemotaxis
Positive Regulation Of Phosphoprotein Phosphatase Activity
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Vasodilation
Positive Regulation Of Neuron Apoptotic Process
Cellular Extravasation
Pathways
Axon guidance
Laminin interactions
ECM proteoglycans
L1CAM interactions
Non-integrin membrane-ECM interactions
Platelet Adhesion to exposed collagen
CHL1 interactions
Axon guidance
Laminin interactions
Semaphorin interactions
Other semaphorin interactions
Smooth Muscle Contraction
L1CAM interactions
Integrin cell surface interactions
Drugs
Diseases
GWAS
Response to citalopram treatment (
22760553
)
Type 2 diabetes (
22693455
)
Alzheimer's disease biomarkers (
23419831
)
Liver enzyme levels (gamma-glutamyl transferase) (
22001757
)
Pulmonary function (
21946350
)
Pulmonary function (interaction) (
23284291
)
Response to platinum-based agents (
22020760
)
Protein-Protein Interactions
19 interactors:
ACHE
APCS
APP
C3
COL7A1
DAG1
FBLN2
HSPG2
ITGA1
ITGA2
ITGB1
MEP1A
NID1
NT5E
PLAT
PLG
SAA1
SAA2
TMPRSS6
10 interactors:
AUP1
BIN1
COL13A1
COL8A1
ITGB1
LAMA1
MATN1
PTPN2
SHARPIN
TLN1
Entrez ID
284217
3672
HPRD ID
01033
01892
Ensembl ID
ENSG00000101680
Uniprot IDs
P25391
P56199
PDB IDs
1PT6
1QC5
1QCY
2L8S
4A0Q
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix Organization
Extracellular Structure Organization
Blood Coagulation
Hemostasis
Response To Wounding
Cell-matrix Adhesion
Regulation Of Body Fluid Levels
Negative Regulation Of Wound Healing
Wound Healing
Cell-substrate Adhesion
Extracellular Matrix Disassembly
Cell Adhesion
Fibrinolysis
Regulation Of Inflammatory Response
Locomotion
Regulation Of Wound Healing
Acute-phase Response
Viral Entry Into Host Cell
Chemotaxis
Entry Into Host Cell
Regulation Of Cell Adhesion
Positive Regulation Of Cell Adhesion
Movement Of Cell Or Subcellular Component
Axon Guidance
Negative Regulation Of Blood Coagulation
Response To Stress
Regulation Of Cell-substrate Adhesion
Negative Regulation Of Coagulation
Acute Inflammatory Response
Leukocyte Migration
Cell Migration
Axonogenesis
Cell Motility
Cell Adhesion Mediated By Integrin
Basement Membrane Organization
Axon Development
Positive Regulation Of Endocytosis
Regulation Of Blood Coagulation
Cell Morphogenesis Involved In Neuron Differentiation
Interaction With Host
Negative Regulation Of Inflammatory Response
Positive Regulation Of Cell-substrate Adhesion
Integrin-mediated Signaling Pathway
Neuron Projection Morphogenesis
Regulation Of Protein Metabolic Process
Formation Of Primary Germ Layer
Negative Regulation Of Proteolysis
Negative Regulation Of Protein Processing
Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Transport
Cell Differentiation
Extracellular Matrix Organization
Extracellular Structure Organization
System Development
Multicellular Organismal Development
Anatomical Structure Development
Cell Adhesion
Developmental Process
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Organ Development
Single Organismal Cell-cell Adhesion
Regulation Of Cell Adhesion
Anatomical Structure Morphogenesis
Cell Morphogenesis Involved In Differentiation
Tissue Development
Collagen Catabolic Process
Cellular Component Assembly
Organ Morphogenesis
Axon Guidance
Negative Regulation Of Interleukin-4-mediated Signaling Pathway
Negative Regulation Of Prolactin Signaling Pathway
Negative Regulation Of Positive Thymic T Cell Selection
Negative Regulation Of Tyrosine Phosphorylation Of Stat1 Protein
Negative Regulation Of Tyrosine Phosphorylation Of Stat6 Protein
Negative Regulation Of Macrophage Colony-stimulating Factor Signaling Pathway
Growth Plate Cartilage Chondrocyte Morphogenesis
Negative Regulation Of Interleukin-2-mediated Signaling Pathway
Collagen Metabolic Process
Cell Morphogenesis
Blood Vessel Morphogenesis
Endochondral Bone Morphogenesis
Multicellular Organismal Macromolecule Metabolic Process
Multicellular Organismal Metabolic Process
Extracellular Matrix Disassembly
Regulation Of Cytokine-mediated Signaling Pathway
Positive Regulation Of Endocytosis
B Cell Differentiation
Negative Regulation Of Inflammatory Response
Blood Vessel Development
Nervous System Development
Lipid Tube Assembly
Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Positive Regulation Of Cell-substrate Adhesion
Cell-cell Junction Assembly
Axonogenesis
Vasculature Development
Bone Morphogenesis
Axon Development
Formation Of Primary Germ Layer
Tagcloud
?
annexin2
col1a1
committed
desensitized
ecm
fbln1
fbn2
fibrillin
fibullin
fn1
has1
hsc
hyaluronan
ifi
ifi44l
ifit1
ifnbeta
isgf3
laminin
mineralization
modifies
niche
opn
osteoblast
osteoblasts
osteoimmunology
osteopontin
pinpoints
timing
Tagcloud (Difference)
?
annexin2
col1a1
committed
desensitized
ecm
fbln1
fbn2
fibrillin
fibullin
fn1
has1
hsc
hyaluronan
ifi
ifi44l
ifit1
ifnbeta
isgf3
laminin
mineralization
modifies
niche
opn
osteoblast
osteoblasts
osteoimmunology
osteopontin
pinpoints
timing
Tagcloud (Intersection)
?