JADE1 and PFDN1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		JADE1	PFDN1
Gene Name		jade family PHD finger 1	prefoldin subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytoplasm Plasma Membrane Intercellular Bridge	Prefoldin Complex
	Molecular Function	RNA Polymerase II Transcription Coactivator Activity Protein Binding Zinc Ion Binding	Sequence-specific DNA Binding Transcription Factor Activity Unfolded Protein Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Apoptotic Process Response To Stress Negative Regulation Of Cell Growth Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Transcription, DNA-templated Protein Folding Cell Cycle Telencephalon Development Cerebellum Development Actin Cytoskeleton Organization B Cell Activation Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: AKT1 CCDC94 CTNNB1 HIST2H3C HMOX2 ING4 KAT7 MEAF6 PFDN1 SEPT8 SMN1 TK1 UBE2E1 UBE2H UBE3A VHL	54 interactors: ACTA1 ACTB ALB ASNA1 BRK1 CCDC85A CHGA DCTN1 DEFA1 DGCR14 EDRF1 EIF3C EIF4A2 EOMES EXT2 EZH2 FAM20C GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 KIAA1377 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 TUBA1A YEATS4 ZNF235
Entrez ID		79960	5201
HPRD ID		10151	05357
Ensembl ID		ENSG00000077684	ENSG00000113068
Uniprot IDs		Q6IE81	O60925
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H4-K12 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Protein K48-linked Ubiquitination Histone H3 Acetylation Histone H4 Acetylation Protein Ubiquitination Protein Modification By Small Protein Conjugation Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Cellular Metabolic Process Protein Acetylation Histone Modification Cell Cycle Protein Polyubiquitination Gland Development Cellular Protein Modification Process Androgen Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Myelination Chromatin Modification Regulation Of RNA Metabolic Process Protein Catabolic Process Peptidyl-lysine Modification Sperm Entry Glycogen Cell Differentiation Involved In Embryonic Placenta Development Fetal Process Involved In Parturition Response To Hypoxia Prostate Gland Development Chromatin Organization Cellular Response To Mechanical Stimulus Regulation Of Gene Expression Intracellular Steroid Hormone Receptor Signaling Pathway Execution Phase Of Apoptosis Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Chromosome Segregation Multicellular Organismal Reproductive Process Negative Regulation Of Mitotic Cell Cycle, Embryonic Skeletal Muscle Cell Proliferation Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition	Organelle Organization Cellular Localization Cellular Macromolecule Biosynthetic Process Cellular Component Assembly Macromolecule Biosynthetic Process Gene Expression Membrane Organization RNA Biosynthetic Process Cellular Protein Localization Establishment Of Protein Localization To Membrane Protein Localization Developmental Process Cerebral Cortex Regionalization Mitotic Cell Cycle Biosynthetic Process Cellular Process Cytoskeleton-dependent Intracellular Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Metabolic Process Establishment Of Localization In Cell Anatomical Structure Development RNA Metabolic Process Organelle Localization 'de Novo' Posttranslational Protein Folding Intracellular Transport Cell Cycle Process 'de Novo' Protein Folding Regulation Of Metabolic Process Telencephalon Regionalization Regulation Of Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Positive Regulation Of Cellular Metabolic Process Protein Localization To Membrane Vesicle Localization Regulation Of Cilium Assembly Multicellular Organismal Development Regulation Of Cellular Process Regulation Of Mitotic Cell Cycle Phase Transition Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Killing Of Cells Of Other Organism Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Anatomical Structure Formation Involved In Morphogenesis
Tagcloud ?		acetylates acetylation bulk ceased demonstrating diminished epithelial h4 hbo1 histones implicate injured isoforms kidneys lysine lysines marks mcm7 nuclei reached recovered recovery regenerating reperfusion replication returned tubular
Tagcloud (Difference) ?		acetylates acetylation bulk ceased demonstrating diminished epithelial h4 hbo1 histones implicate injured isoforms kidneys lysine lysines marks mcm7 nuclei reached recovered recovery regenerating reperfusion replication returned tubular
Tagcloud (Intersection) ?