NASP and H3-5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		NASP	H3-5
Description		nuclear autoantigenic sperm protein	H3.5 histone
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex	Nucleosome Euchromatin Nucleus Nucleoplasm Chromosome
	Molecular Function	Protein Binding Histone Binding Protein-containing Complex Binding	DNA Binding Protein Binding Structural Constituent Of Chromatin Nucleosomal DNA Binding Protein Heterodimerization Activity
	Biological Process	Blastocyst Development DNA Replication Nucleosome Assembly DNA Replication-dependent Chromatin Assembly Male Gonad Development Protein Transport Response To Testosterone CENP-A Containing Chromatin Assembly	Positive Regulation Of Cell Growth
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		22 interacting genes: CDC42 FXR2 H1-1 H1-2 H3-3B H3-4 H3-5 H3C10 H3C13 H3C14 H3C4 H3C8 HDAC6 ITSN1 LUC7L2 MTNR1A OGT PTK2 TERF2 TERF2IP TIAM1 ULK2	15 interacting genes: DAXX DNAJC9 FBLIM1 KAT6A KDM1A KDM4B NASP NSD3 PRMT5 PRMT6 PRMT7 SETMAR SMYD1 SMYD3 SUV39H1
Entrez ID		4678	440093
HPRD ID		04423	18443
Ensembl ID		ENSG00000132780	ENSG00000188375
Uniprot IDs		P49321 Q5T626	Q6NXT2
PDB IDs		7V1K 7V1L 7V1M 7V6P 7V6Q	2PUY 3KV4 4Z5T 5BWN 5BWO 5F6K 5I3L 6OI3 7TRL 7W67 7W6I 7W6J 7W6L 7Y0I 7ZEZ 8Q1G 8Q1H 8Q1J 8RBX 8SR6 8T4F 8T4R 8ZXC 9C0O 9DZN
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Chromatin Nucleosome Nucleosome Assembly Nucleosome Organization Protein-DNA Complex Assembly Chromosome Protein-containing Complex Organization Protein Heterodimerization Activity Protein-containing Complex Assembly Cellular Component Assembly Chromatin Organization Chromatin Remodeling Chromosome Organization Telomere Organization Nucleosomal DNA Binding Negative Regulation Of DNA Recombination Epigenetic Regulation Of Gene Expression Negative Regulation Of DNA Recombination At Telomere Regulation Of Cellular Component Organization Shelterin Complex Organelle Organization Negative Regulation Of Cellular Component Organization Negative Regulation Of DNA Metabolic Process DNA Binding Regulation Of DNA Recombination Protection From Non-homologous End Joining At Telomere Gene Expression Protein-containing Complex Macromolecule Biosynthetic Process Nuclear Telomere Cap Complex Mitophagy Euchromatin Nucleus G-rich Strand Telomeric DNA Binding Chromosome, Telomeric Region Protein Localization To Chromosome, Telomeric Region Nucleoplasm Telomere Capping Autophagy Of Mitochondrion Telomere Maintenance In Response To DNA Damage Negative Regulation Of Chromosome Organization Regulation Of Cell Growth Chromatin DNA Binding Collateral Sprouting Dendritic Spine Morphogenesis Positive Regulation Of Cellular Component Organization RNA-templated DNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Telomeric DNA Binding Negative Regulation Of Protein-containing Complex Assembly	Chromatin Remodeling Chromatin Organization Histone Methyltransferase Activity Methyltransferase Activity Methylation Histone H3 Methyltransferase Activity Histone H4R3 Methyltransferase Activity Nucleosome Assembly Protein-arginine N-methyltransferase Activity Nucleosome Organization Histone Binding Histone H3K4 Methyltransferase Activity Protein-DNA Complex Assembly Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Transferase Activity Regulation Of Signal Transduction By P53 Class Mediator Histone H3K36 Dimethyltransferase Activity Nucleoplasm Peptidyl-arginine Methylation Protein-arginine Omega-N Monomethyltransferase Activity Nucleus Chromosome Histone H4 Methyltransferase Activity Transcription Corepressor Activity Histone H3K4 Trimethyltransferase Activity Regulation Of Nucleobase-containing Compound Metabolic Process P53 Binding Histone H3K36 Methyltransferase Activity Histone H3K9 Demethylase Activity Protein-containing Complex Assembly Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Epigenetic Regulation Of Gene Expression Negative Regulation Of RNA Metabolic Process Protein-containing Complex Organization Regulation Of RNA Metabolic Process Positive Regulation Of ATP-dependent Activity Histone Demethylase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Chromatin Nuclear Androgen Receptor Binding Histone Methyltransferase Complex S-adenosylmethionine-dependent Methyltransferase Activity Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of ATP-dependent Activity
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