NASP and HIST1H1A

Number of citations of the paper that reports this interaction (PMID 10893414)
38

Data Source:
HPRD (in vivo, in vitro)

		NASP	HIST1H1A
Gene Name		nuclear autoantigenic sperm protein (histone-binding)	histone cluster 1, H1a
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Protein Complex	Nucleosome Nuclear Chromatin Nuclear Euchromatin
	Molecular Function	Histone Binding Hsp90 Protein Binding	Protein Binding Chromatin DNA Binding
	Biological Process	Blastocyst Development DNA Replication DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Cell Cycle Cell Proliferation Protein Transport Histone Exchange	Nucleosome Assembly Spermatogenesis
Pathways			DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Cellular Senescence Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: H3F3B H3F3C HDAC6 HIST1H1A HIST1H1C HIST1H3G HIST1H3H HIST1H4A HIST2H3C LUC7L2 PTK2 TERF2 TERF2IP ULK2	45 interactors: AEBP2 CCNA1 CCNA2 CCNB1 CCND2 CCNE1 CDK1 CDK2 CDK4 CDK6 CDK7 CDKN1B CRP CTCFL EED EHMT2 EP300 EZH2 GADD45A GZMA IRAK4 KAT2B LIMK1 LIMK2 LOX NAP1L4 NASP PARP1 PARP3 PELP1 PKN1 PRDM1 PRKCA PRKCB PRKCD PRKCE PRKCZ PRKDC PTMA RBBP4 SUZ12 TERF1 TERF2IP TLK1 WHSC1L1
Entrez ID		4678	3024
HPRD ID		04423	00820
Ensembl ID		ENSG00000132780	ENSG00000124610
Uniprot IDs		P49321 Q5T626	Q02539
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Chromatin Silencing At RDNA Chromatin Silencing Nucleosome Assembly Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly DNA Methylation Protein-DNA Complex Assembly Negative Regulation Of Gene Expression, Epigenetic DNA Packaging Cellular Macromolecular Complex Assembly Chromosome Organization DNA Modification Regulation Of Gene Expression, Epigenetic Chromatin Organization Gene Silencing DNA Conformation Change Cellular Component Assembly DNA Replication-dependent Nucleosome Assembly Organelle Organization Protein Complex Assembly DNA Metabolic Process Protection From Non-homologous End Joining At Telomere Telomere Capping Methylation Blood Coagulation Hemostasis Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Telomere Maintenance Regulation Of Body Fluid Levels Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Wound Healing Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Stress Response To Wounding Regulation Of Cellular Component Organization Regulation Of Telomere Maintenance Negative Regulation Of Gene Expression RNA-dependent DNA Replication Regulation Of Gene Silencing Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening DNA Replication-independent Nucleosome Assembly Gene Expression	Chromosome Organization Cell Cycle Chromatin Organization Chromatin Modification Regulation Of Cell Cycle Organelle Organization Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Histone Modification Regulation Of Metabolic Process Mitotic Cell Cycle Process Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Nitrogen Compound Metabolic Process Cellular Protein Metabolic Process G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Protein Phosphorylation Regulation Of Mitotic Cell Cycle Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Cell Division Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle DNA Metabolic Process Cellular Response To Stress Response To Stress Histone Phosphorylation Regulation Of Catalytic Activity Peptidyl-amino Acid Modification Cellular Metabolic Process Regulation Of Cell Cycle Process Phosphorylation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression, Epigenetic
Tagcloud ?		1990s aerial barkley canada concentrated discharge discharges effort entrance fit fuca grid harbours inform inputs juan oily operations output pacific scenarios shore sound strait surveillance tourist trying vessel zeros
Tagcloud (Difference) ?		1990s aerial barkley canada concentrated discharge discharges effort entrance fit fuca grid harbours inform inputs juan oily operations output pacific scenarios shore sound strait surveillance tourist trying vessel zeros
Tagcloud (Intersection) ?