YTHDC1 and SEPTIN10

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		YTHDC1	SEPTIN10
Description		YTH N6-methyladenosine RNA binding protein C1	septin 10
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane Nuclear Speck	Cytoplasm Cytoskeleton Cilium Septin Ring Microtubule Cytoskeleton Septin Complex Motile Cilium Cell Division Site Cell Projection
	Molecular Function	RNA Binding MRNA Binding Protein Binding N6-methyladenosine-containing RNA Reader Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Recognition MRNA Processing MRNA Export From Nucleus Spermatogenesis RNA Splicing Dosage Compensation By Inactivation Of X Chromosome Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Primary Follicle Stage MRNA Alternative Polyadenylation	Intracellular Protein Localization Cell Division Cytoskeleton-dependent Cytokinesis
Pathways		Nuclear RNA decay
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Obesity-related traits ( 23251661)	Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		41 interacting genes: ABL1 ADAMTS4 ANKRD28 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 KRTAP10-6 LAMC3 LAMTOR5 LZTS2 PHF19 PICK1 PLG PROSER2 RBMY1A1 RBMY1F RBMY1J RNPS1 SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51	3 interacting genes: H2AP LSM8 YTHDC1
Entrez ID		91746	151011
HPRD ID		11689	15325
Ensembl ID		ENSG00000083896	ENSG00000186522
Uniprot IDs		J3QR07 Q96MU7	B5ME97 B7Z277 B7Z371 E7EW69 Q59H84 Q9H9P7 Q9P0V9
PDB IDs		2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7 6SYZ 6SZ1 6SZ2 6SZ3 6SZL 6SZN 6SZR 6SZT 6SZX 6SZY 6T01 6T02 6T03 6T04 6T05 6T06 6T07 6T08 6T09 6T0A 6T0C 6T0D 6T0O 6T0X 6T0Z 6T10 6T11 6T12 6WE8 6WE9 6WEA 6YKE 6YKI 6YKJ 6YKZ 6YL0 6YL8 6YL9 6YM2 6YM8 6YNI 6YNJ 6YNK 6YNL 6YNM 6YNN 6YNO 6YNP 6YOQ 6ZCM 6ZCN 6ZD9 7L4X 7L4Y 7P87 7P88 7P8A 7P8B 7P8F 7PJ7 7PJ8 7PJ9 7PJA 7PJB 7PJP 7PJQ 7PO6 8K2E 8Q2Q 8Q2R 8Q2S 8Q2T 8Q2U 8Q2V 8Q2W 8Q2X 8Q2Y 8Q31 8Q32 8Q33 8Q35 8Q37 8Q38 8Q39 8Q3A 8Q3G 8Q4M 8Q4N 8Q4P 8Q4Q 8Q4R 8Q4T 8Q4U 8Q4V 8Q4W
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process MRNA Processing MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Splicing Positive Regulation Of RNA Splicing RNA Processing Nucleic Acid Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Domain Specific Binding Non-membrane Spanning Protein Tyrosine Kinase Activity MRNA Binding RNA Binding Spliceosomal Complex RNA Metabolic Process Protein Tyrosine Kinase Activity Macromolecule Metabolic Process SH2 Domain Binding Nucleoplasm Nuclear Speck Nucleic Acid Metabolic Process Regulation Of Macromolecule Biosynthetic Process Protein Phosphorylation Positive Regulation Of Gene Expression Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Protein Kinase Activity Positive Regulation Of MRNA Metabolic Process Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Gene Expression Phosphorylation Regulation Of RNA Metabolic Process Identical Protein Binding Ephrin Receptor Binding Nucleus Regulation Of Primary Metabolic Process Nucleolus Fc-gamma Receptor Signaling Pathway Kinase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome T Cell Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Negative Regulation Of Actin Nucleation Activated T Cell Proliferation Ephrin Receptor Signaling Pathway	Heterochromatin Formation Negative Regulation Of Gene Expression, Epigenetic MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Primary Follicle Stage Mammalian Oogenesis Stage Epigenetic Regulation Of Gene Expression MRNA Binding MRNA Alternative Polyadenylation Lsm2-8 Complex RNA Splicing U6 SnRNP MRNA Processing N6-methyladenosine-containing RNA Reader Activity U6 SnRNA Binding Precatalytic Spliceosome MRNA Metabolic Process Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Chromatin Remodeling MRNA 3'-end Processing MRNA Splice Site Recognition Chromatin Organization U4/U6 X U5 Tri-snRNP Complex RNA Processing U2-type Precatalytic Spliceosome Negative Regulation Of Gene Expression MRNA Export From Nucleus Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Export From Nucleus RNA 3'-end Processing
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