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YTHDC1 and SRPK2
Number of citations of the paper that reports this interaction (PMID
23602568
)
8
Data Source:
BioGRID
(affinity chromatography technology, fluorescent resonance energy transfer, affinity chromatography technology)
YTHDC1
SRPK2
Gene Name
YTH domain containing 1
SRSF protein kinase 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nuclear Body
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Molecular Function
RNA Binding
Protein Binding
Poly(A) RNA Binding
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
14-3-3 Protein Binding
Biological Process
MRNA Splice Site Selection
Spliceosomal Complex Assembly
Angiogenesis
Protein Phosphorylation
Positive Regulation Of Cell Proliferation
RNA Splicing
Positive Regulation Of Gene Expression
Cell Differentiation
Nuclear Speck Organization
Intracellular Signal Transduction
Positive Regulation Of Neuron Apoptotic Process
Positive Regulation Of Viral Genome Replication
Negative Regulation Of Viral Genome Replication
Innate Immune Response
Positive Regulation Of Cell Cycle
Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Myopia (pathological) (
23049088
)
Protein-Protein Interactions
34 interactors:
ABL1
ADAMTS4
CFH
CLK2
CORO1A
DVL3
EDC4
EMD
FYN
GOLGA2
HNRNPK
KHDRBS1
KHDRBS2
KHDRBS3
KRT18
LAMC3
LAMTOR5
LZTS2
MPRIP
PLG
PROSER2
RBMY1F
SDCBP2
SEPT10
SOX13
SRC
SRPK1
SRPK2
SRSF1
SRSF2
TRA2A
TRA2B
TXK
VPS51
177 interactors:
ABL1
ACIN1
ADPRH
AES
AHCYL1
ALKBH3
AMMECR1L
APEX1
APOBEC3C
APP
ARGLU1
ARHGAP12
ARL6IP4
ARPC1B
ATAT1
AURKA
BAIAP2
BRD3
C16orf78
C17orf85
C18orf25
C1orf35
C4orf46
CACNG2
CAND1
CASK
CBLN4
CBX5
CCDC28A
CCDC97
CCM2
CDC42EP4
CDK7
CHD2
CHERP
CHTOP
CHUK
CLDN19
CLK1
CLK2
CLK3
CSAG1
CTNNBL1
DAW1
DBF4B
DDX21
DDX46
DDX6
DHX8
DNAJC8
DRAP1
DRG1
EGLN2
EIF1AY
ENOX2
EPB41L1
EPB41L4A
EPS8L3
ERCC3
ERN1
EVI5L
FAM76B
FAM90A1
FGF12
FOXN3
FXR2
GABARAP
GABARAPL1
GPR114
GTF2E1
HBS1L
HIRIP3
HMGN3
HNRNPC
HOMER3
IFIT5
KCNN2
LCA5
LCE3D
LRRN4CL
LUC7L
LUC7L2
LUC7L3
LUZP4
MAB21L2
MAGEB1
MAPKAPK5
MARCH10
MCOLN3
MDK
MPP3
MRPS6
NCK2
NELFE
NGLY1
NOP16
NPM2
NSMCE4A
NSRP1
NUP50
NXT2
OCEL1
PABPC4
PAK4
PDE7B
PELI1
POLB
PPIA
PPIL1
PRKAA1
PRPF38A
PRPF40A
PSMA3
PTBP1
RBM15
RBM23
RBM39
RBM8A
RIT1
RIT2
RNF4
RNPS1
RPL22
RPL39L
RPL41
RSRC1
RSRC2
RSRP1
RTF1
RWDD2B
SDR42E1
SEC23B
SLAIN2
SNIP1
SNRNP27
SNRNP35
SNRNP70
SNURF
SREK1
SRI
SRRM1
SRSF1
SRSF12
SRSF3
SRSF5
SRSF7
SRSF8
SRSF9
STON1
SUPT16H
TAF7L
TCOF1
TDP2
TLE4
TNFRSF10C
TNIP2
TPD52
TRA2A
TRA2B
TRIM41
TTN
U2AF1
U2AF2
UBD
UBE2E2
VAV2
VIMP
VRK1
WDR5
YPEL2
YPEL3
YTHDC1
YWHAB
ZMAT4
ZRANB2
ZRSR2
ZSCAN9
Entrez ID
91746
6733
HPRD ID
11689
04280
Ensembl ID
ENSG00000083896
ENSG00000135250
Uniprot IDs
J3QR07
Q96MU7
P78362
PDB IDs
2YUD
2X7G
Enriched GO Terms of Interacting Partners
?
MRNA Metabolic Process
MRNA Processing
RNA Splicing
RNA Processing
Peptidyl-tyrosine Autophosphorylation
Regulation Of RNA Splicing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of MRNA Processing
Protein Autophosphorylation
Regulation Of Cell-cell Adhesion
RNA Metabolic Process
Peptidyl-tyrosine Phosphorylation
Regulation Of Wnt Signaling Pathway
Gene Expression
Viral Process
Innate Immune Response
Regulation Of Cell Proliferation
Cellular Response To Platelet-derived Growth Factor Stimulus
Response To Platelet-derived Growth Factor
Regulation Of Cell Adhesion
Anatomical Structure Development
Leukocyte Migration
Regulation Of Canonical Wnt Signaling Pathway
Immune Response
Regulation Of RNA Metabolic Process
Regulation Of Intracellular Transport
Cytoplasmic Transport
Defense Response
Cell Cycle
Nucleobase-containing Compound Metabolic Process
Regulation Of Cellular Localization
Activated T Cell Proliferation
Phagocytosis
Positive Regulation Of Viral Genome Replication
Regulation Of Neuron Death
Heterocycle Metabolic Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Cellular Aromatic Compound Metabolic Process
Nuclear Export
Regulation Of T Cell Activation
Nucleus Organization
Regulation Of Gene Expression
Developmental Process
Regulation Of Nitrogen Compound Metabolic Process
Antigen Receptor-mediated Signaling Pathway
Cellular Nitrogen Compound Metabolic Process
Cellular Process
Golgi To Plasma Membrane Transport
MRNA Processing
MRNA Metabolic Process
RNA Processing
RNA Splicing
Gene Expression
RNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of RNA Splicing
Cellular Metabolic Process
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of MRNA Processing
DNA-templated Transcription, Termination
Termination Of RNA Polymerase II Transcription
MRNA 3'-end Processing
MRNA Export From Nucleus
MRNA Transport
RNA Export From Nucleus
RNA 3'-end Processing
RNA Transport
Negative Regulation Of MRNA Splicing, Via Spliceosome
RNA Localization
Nuclear Export
MRNA Splice Site Selection
Negative Regulation Of RNA Splicing
Spliceosomal Complex Assembly
Nucleocytoplasmic Transport
Nuclear Transport
Cellular Process
RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Cytoplasmic Transport
Ribonucleoprotein Complex Assembly
Transcription, DNA-templated
Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Ribonucleoprotein Complex Biogenesis
Intracellular Transport
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Establishment Of Localization In Cell
Transcription From RNA Polymerase II Promoter
Regulation Of Cell Cycle
Tagcloud
?
70k
arginine
asf
clk
cloning
coexpressed
contributing
dipeptides
nh2
pancreas
phosphorylate
preference
preferred
proline
redistribution
reversible
rs
sf2
similarities
spliceosome
splicing
srpk1
stringent
sty
u1
uniquely
ww
Tagcloud (Difference)
?
70k
arginine
asf
clk
cloning
coexpressed
contributing
dipeptides
nh2
pancreas
phosphorylate
preference
preferred
proline
redistribution
reversible
rs
sf2
similarities
spliceosome
splicing
srpk1
stringent
sty
u1
uniquely
ww
Tagcloud (Intersection)
?