YTHDC1 and TRA2B

Number of citations of the paper that reports this interaction (PubMedID 9473574)
0

Data Source:
HPRD (two hybrid, in vitro)

		YTHDC1	TRA2B
Description		YTH N6-methyladenosine RNA binding protein C1	transformer 2 beta homolog
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane Nuclear Speck	Nucleus Nuclear Inner Membrane Nucleoplasm Spliceosomal Complex Protein-containing Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding N6-methyladenosine-containing RNA Reader Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Pre-mRNA Binding Identical Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Recognition MRNA Processing MRNA Export From Nucleus Spermatogenesis RNA Splicing Dosage Compensation By Inactivation Of X Chromosome Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Primary Follicle Stage MRNA Alternative Polyadenylation	RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cerebral Cortex Regionalization Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Glucose Stimulus Embryonic Brain Development
Pathways		Nuclear RNA decay	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Obesity-related traits ( 23251661)	Appendicular lean mass ( 33097823) Height ( 31562340) Menarche (age at onset) ( 21102462 25231870 27182965) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		41 interacting genes: ABL1 ADAMTS4 ANKRD28 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 KRTAP10-6 LAMC3 LAMTOR5 LZTS2 PHF19 PICK1 PLG PROSER2 RBMY1A1 RBMY1F RBMY1J RNPS1 SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51	107 interacting genes: - CDK6 CLK1 CLK3 EPM2AIP1 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM MAGOHB MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYPOP NGFR NXF1 PCDHB14 RBMX RBMXL2 RBMY1A1 RBMY1F RBMY1J RNPS1 SREK1 SRPK1 SRSF10 SRSF2 SRSF3 SRSF4 SRSF8 SRSF9 TNPO3 U2AF1 YTHDC1 YWHAG YWHAZ ZRANB2
Entrez ID		91746	6434
HPRD ID		11689	04097
Ensembl ID		ENSG00000083896	ENSG00000136527
Uniprot IDs		J3QR07 Q96MU7	P62995
PDB IDs		2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7 6SYZ 6SZ1 6SZ2 6SZ3 6SZL 6SZN 6SZR 6SZT 6SZX 6SZY 6T01 6T02 6T03 6T04 6T05 6T06 6T07 6T08 6T09 6T0A 6T0C 6T0D 6T0O 6T0X 6T0Z 6T10 6T11 6T12 6WE8 6WE9 6WEA 6YKE 6YKI 6YKJ 6YKZ 6YL0 6YL8 6YL9 6YM2 6YM8 6YNI 6YNJ 6YNK 6YNL 6YNM 6YNN 6YNO 6YNP 6YOQ 6ZCM 6ZCN 6ZD9 7L4X 7L4Y 7P87 7P88 7P8A 7P8B 7P8F 7PJ7 7PJ8 7PJ9 7PJA 7PJB 7PJP 7PJQ 7PO6 8K2E 8Q2Q 8Q2R 8Q2S 8Q2T 8Q2U 8Q2V 8Q2W 8Q2X 8Q2Y 8Q31 8Q32 8Q33 8Q35 8Q37 8Q38 8Q39 8Q3A 8Q3G 8Q4M 8Q4N 8Q4P 8Q4Q 8Q4R 8Q4T 8Q4U 8Q4V 8Q4W	2CQC 2KXN 2RRA 2RRB
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process MRNA Processing MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Splicing Positive Regulation Of RNA Splicing RNA Processing Nucleic Acid Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Domain Specific Binding Non-membrane Spanning Protein Tyrosine Kinase Activity MRNA Binding RNA Binding Spliceosomal Complex RNA Metabolic Process Protein Tyrosine Kinase Activity Macromolecule Metabolic Process SH2 Domain Binding Nucleoplasm Nuclear Speck Nucleic Acid Metabolic Process Regulation Of Macromolecule Biosynthetic Process Protein Phosphorylation Positive Regulation Of Gene Expression Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Protein Kinase Activity Positive Regulation Of MRNA Metabolic Process Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Gene Expression Phosphorylation Regulation Of RNA Metabolic Process Identical Protein Binding Ephrin Receptor Binding Nucleus Regulation Of Primary Metabolic Process Nucleolus Fc-gamma Receptor Signaling Pathway Kinase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome T Cell Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Negative Regulation Of Actin Nucleation Activated T Cell Proliferation Ephrin Receptor Signaling Pathway	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Extracellular Vesicle Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Negative Regulation Of Translation Regulation Of Metabolic Process Positive Regulation Of MRNA Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Locomotion Negative Regulation Of Cytokine Production Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of Translation Regulation Of MRNA Stability Regulation Of RNA Stability Negative Regulation Of Protein Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Developmental Process Regulation Of Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Extracellular Space Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
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