YTHDC1 and TRA2A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		YTHDC1	TRA2A
Gene Name		YTH domain containing 1	transformer 2 alpha homolog (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Body	Nucleus Nucleolus Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding Poly(A) RNA Binding
	Biological Process	MRNA Splice Site Selection	MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		34 interactors: ABL1 ADAMTS4 CFH CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 LAMC3 LAMTOR5 LZTS2 MPRIP PLG PROSER2 RBMY1F SDCBP2 SEPT10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51	17 interactors: C11orf58 CDK2AP2 CDK6 CRABP1 DHX15 LBP NUDT21 NXF1 PPP1CC RNPS1 SELENBP1 SRPK2 SRSF10 TNNT1 U2SURP YTHDC1 YWHAG
Entrez ID		91746	29896
HPRD ID		11689	04096
Ensembl ID		ENSG00000083896	ENSG00000164548
Uniprot IDs		J3QR07 Q96MU7	B4DUA9 Q13595 Q549U1
PDB IDs		2YUD
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Peptidyl-tyrosine Autophosphorylation Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Protein Autophosphorylation Regulation Of Cell-cell Adhesion RNA Metabolic Process Peptidyl-tyrosine Phosphorylation Regulation Of Wnt Signaling Pathway Gene Expression Viral Process Innate Immune Response Regulation Of Cell Proliferation Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Regulation Of Cell Adhesion Anatomical Structure Development Leukocyte Migration Regulation Of Canonical Wnt Signaling Pathway Immune Response Regulation Of RNA Metabolic Process Regulation Of Intracellular Transport Cytoplasmic Transport Defense Response Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Localization Activated T Cell Proliferation Phagocytosis Positive Regulation Of Viral Genome Replication Regulation Of Neuron Death Heterocycle Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Aromatic Compound Metabolic Process Nuclear Export Regulation Of T Cell Activation Nucleus Organization Regulation Of Gene Expression Developmental Process Regulation Of Nitrogen Compound Metabolic Process Antigen Receptor-mediated Signaling Pathway Cellular Nitrogen Compound Metabolic Process Cellular Process Golgi To Plasma Membrane Transport	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome RNA Export From Nucleus Regulation Of MRNA Processing Regulation Of RNA Splicing MRNA Transport Nuclear Export Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing RNA Transport RNA Localization Ribonucleoprotein Complex Assembly Termination Of RNA Polymerase II Transcription MRNA Splice Site Selection Nucleocytoplasmic Transport Nuclear Transport Cell Dedifferentiation Nuclear Speck Organization Gene Expression DNA-templated Transcription, Termination Ribonucleoprotein Complex Biogenesis MRNA 3'-end Processing Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response Lipopolysaccharide Transport RNA 3'-end Processing RNA Metabolic Process Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Respiratory Burst Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Cellular Senescence Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death
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