AP3S1 and RUFY1

Number of citations of the paper that reports this interaction (PMID 23144738)
1

Data Source:
BioGRID (pull down)

		AP3S1	RUFY1
Gene Name		adaptor-related protein complex 3, sigma 1 subunit	RUN and FYVE domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus AP-type Membrane Coat Adaptor Complex AP-3 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane	Nucleus Cytoplasm Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Transporter Activity Protein Binding Protein Transporter Activity	Protein Binding Zinc Ion Binding Lipid Binding Protein Transporter Activity
	Biological Process	Intracellular Protein Transport Anterograde Axon Cargo Transport Insulin Receptor Signaling Pathway Anterograde Synaptic Vesicle Transport	Endocytosis Protein Transport Regulation Of Endocytosis
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS			Eating disorders ( 22911880)
Protein-Protein Interactions		7 interactors: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3	17 interactors: AP3B2 AP3D1 AP3M1 AP3S1 BMX DIEXF EPHA3 GIT2 ITSN2 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TCF3 TXNDC17
Entrez ID		1176	80230
HPRD ID		03298	15282
Ensembl ID			ENSG00000176783
Uniprot IDs		Q92572	A8K7B1 Q96T51
PDB IDs			2YQM 2YW8
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Anterograde Axon Cargo Transport Axon Cargo Transport Regulation Of Sequestering Of Zinc Ion Protein Localization Synaptic Vesicle Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Vesicle Localization Intracellular Protein Transport Microtubule-based Movement Establishment Of Organelle Localization Organelle Localization Cellular Localization Protein Localization To Organelle Vesicle-mediated Transport Transport Synaptic Transmission Intracellular Transport Synaptic Vesicle Membrane Organization Regulation Of Ion Homeostasis Microtubule-based Process Eye Pigment Biosynthetic Process Establishment Of Localization In Cell Cell-cell Signaling Positive Regulation Of NK T Cell Differentiation Eye Pigmentation Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Endosome To Melanosome Transport Pigment Granule Maturation Cellular Pigment Accumulation Positive Regulation Of Fatty Acid Beta-oxidation Protein Targeting To Lysosome Positive Regulation Of Glycogen Biosynthetic Process Protein Localization To Lysosome Positive Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Glucose Import In Response To Insulin Stimulus Melanosome Organization Protein Targeting To Vacuole JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Pigment Granule Organization Phosphatidylinositol 3-kinase Signaling Movement Of Cell Or Subcellular Component	Anterograde Synaptic Vesicle Transport Intracellular Protein Transport Anterograde Axon Cargo Transport Synaptic Vesicle Transport Axon Cargo Transport Rab Protein Signal Transduction Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Intracellular Transport Vesicle Localization Protein Localization Microtubule-based Transport Establishment Of Organelle Localization Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Signaling Cell Communication Organelle Localization Cellular Localization Ras Protein Signal Transduction Post-Golgi Vesicle-mediated Transport Synaptic Transmission Microtubule-based Movement Cytoplasmic Transport Cell-cell Signaling Endosomal Transport Regulation Of Ras GTPase Activity Transport Phagolysosome Assembly Involved In Apoptotic Cell Clearance Small GTPase Mediated Signal Transduction Golgi Vesicle Transport Regulation Of Ras Protein Signal Transduction Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Synaptic Vesicle Membrane Organization Cellular Response To Stimulus Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Regulation Of GTPase Activity Canonical Wnt Signaling Pathway Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Endosome Size Response To Stimulus Membrane Organization Eye Pigment Biosynthetic Process Movement Of Cell Or Subcellular Component
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