AP3S1 and AP3D1

Number of citations of the paper that reports this interaction (PMID 15469849)
6

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, two hybrid)

		AP3S1	AP3D1
Gene Name		adaptor-related protein complex 3, sigma 1 subunit	adaptor-related protein complex 3, delta 1 subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus AP-type Membrane Coat Adaptor Complex AP-3 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane Membrane Coat Terminal Bouton
	Molecular Function	Transporter Activity Protein Binding Protein Transporter Activity	Transporter Activity
	Biological Process	Intracellular Protein Transport Anterograde Axon Cargo Transport Insulin Receptor Signaling Pathway Anterograde Synaptic Vesicle Transport	Eye Pigment Biosynthetic Process Intracellular Protein Transport Anterograde Axon Cargo Transport Melanosome Organization Protein Localization To Organelle Endosome To Melanosome Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3	9 interactors: AP3S1 AP3S2 ARF1 ARF6 CTGF RUFY1 SLC30A3 VAMP7 VPS41
Entrez ID		1176	8943
HPRD ID		03298	06260
Ensembl ID			ENSG00000065000
Uniprot IDs		Q92572	O14617
PDB IDs			4AFI
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Anterograde Axon Cargo Transport Axon Cargo Transport Regulation Of Sequestering Of Zinc Ion Protein Localization Synaptic Vesicle Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Vesicle Localization Intracellular Protein Transport Microtubule-based Movement Establishment Of Organelle Localization Organelle Localization Cellular Localization Protein Localization To Organelle Vesicle-mediated Transport Transport Synaptic Transmission Intracellular Transport Synaptic Vesicle Membrane Organization Regulation Of Ion Homeostasis Microtubule-based Process Eye Pigment Biosynthetic Process Establishment Of Localization In Cell Cell-cell Signaling Positive Regulation Of NK T Cell Differentiation Eye Pigmentation Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Endosome To Melanosome Transport Pigment Granule Maturation Cellular Pigment Accumulation Positive Regulation Of Fatty Acid Beta-oxidation Protein Targeting To Lysosome Positive Regulation Of Glycogen Biosynthetic Process Protein Localization To Lysosome Positive Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Glucose Import In Response To Insulin Stimulus Melanosome Organization Protein Targeting To Vacuole JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Pigment Granule Organization Phosphatidylinositol 3-kinase Signaling Movement Of Cell Or Subcellular Component	Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of Vesicle-mediated Transport Protein Localization Transport Cellular Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Anterograde Synaptic Vesicle Transport Regulation Of Endocytosis Anterograde Axon Cargo Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization Intracellular Transport Golgi Vesicle Transport Axon Cargo Transport Establishment Of Organelle Localization Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Organelle Fusion Regulation Of Actin Filament-based Process Regulation Of Protein Targeting To Vacuolar Membrane Vacuole Fusion, Non-autophagic Vacuolar Transport Organelle Localization Post-Golgi Vesicle-mediated Transport Regulation Of Cytoskeleton Organization Synaptic Vesicle Transport Organ Senescence Membrane Fusion Microtubule-based Transport Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Triglyceride Transport Extracellular Matrix Constituent Secretion Eosinophil Degranulation Cytoskeleton-dependent Intracellular Transport Response To Anoxia Positive Regulation Of G0 To G1 Transition Movement Of Cell Or Subcellular Component Regulation Of Sequestering Of Zinc Ion Neutrophil Degranulation Positive Regulation Of Cardiac Muscle Contraction Positive Regulation Of Cytoskeleton Organization Vesicle Organization Myeloid Cell Apoptotic Process Regulation Of SNARE Complex Assembly
Tagcloud ?			18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Difference) ?			18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Intersection) ?