AP3S1 and AP3B2

Number of citations of the paper that reports this interaction (PubMedID 9118953)
45

Data Source:
HPRD (in vivo)

		AP3S1	AP3B2
Description		adaptor related protein complex 3 subunit sigma 1	adaptor related protein complex 3 subunit beta 2
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Golgi Apparatus Membrane Membrane Coat AP-type Membrane Coat Adaptor Complex AP-3 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Presynapse Axon Cytoplasm	Early Endosome Golgi Apparatus Membrane Membrane Coat AP-3 Adaptor Complex Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Intracellular Vesicle Presynapse Axon Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Insulin Receptor Signaling Pathway Protein Transport Synaptic Vesicle Coating Vesicle-mediated Transport Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Synaptic Vesicle Recycling Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Melanosome Assembly	Intracellular Protein Transport Anterograde Axonal Transport Protein Transport Synaptic Vesicle Coating Vesicle-mediated Transport Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Synaptic Vesicle Recycling Synaptic Vesicle Endocytosis Anterograde Synaptic Vesicle Transport
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Lipoprotein-associated phospholipase A2 activity change in response to statin therapy ( 23118302) Schizophrenia ( 28991256) Tourette syndrome ( 30818990) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		7 interacting genes: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3	7 interacting genes: ADAP1 AP3S1 ATM CLTC CSNK1A1 ERBB2 RUFY1
Entrez ID		1176	8120
HPRD ID		03298	03699
Ensembl ID		ENSG00000177879	ENSG00000103723
Uniprot IDs		F5H459 Q92572	F5GYB0 Q13367
PDB IDs		9C58 9C59 9C5B 9C5C
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Coating Clathrin-coated Vesicle Cargo Loading, AP-3-mediated AP-3 Adaptor Complex Anterograde Synaptic Vesicle Transport Synaptic Vesicle Recycling Membrane Coat Cellular Localization Vesicle Cargo Loading Synaptic Vesicle Transport Vesicle Coating Vacuolar Transport Anterograde Axonal Transport Vesicle Transport Along Microtubule Zinc Ion Import Into Lysosome Vesicle Cytoskeletal Trafficking Intracellular Transport Axon Cytoplasm Axonal Transport Establishment Of Protein Localization Vacuolar Transmembrane Transport Axo-dendritic Transport Organelle Transport Along Microtubule Vesicle Organization Zinc Ion Import Into Organelle Establishment Of Localization In Cell Establishment Of Vesicle Localization Vesicle Localization Lysosomal Transport Melanosome Assembly Intracellular Membrane-bounded Organelle Golgi To Vacuole Transport Protein Transport Platelet Dense Granule Organization Transport Along Microtubule Intracellular Protein Transport Zinc Ion Transmembrane Transport Vesicle-mediated Transport Zinc Ion Transport Cytoskeleton-dependent Intracellular Transport Protein Targeting Microtubule-based Transport Melanosome Organization Pigment Granule Organization SH2 Domain Binding Establishment Of Organelle Localization Golgi Vesicle Transport Protein Targeting To Vacuole Protein Localization To Lysosome Regulation Of Lipid Catabolic Process Early Endosome	Intracellular Membrane-bounded Organelle Positive Regulation Of Rho Protein Signal Transduction Spindle Establishment Of RNA Localization To Telomere Autophagosome Assembly Negative Regulation Of TOR Signaling Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of TORC1 Signaling Protein Phosphorylation Regulation Of TORC1 Signaling SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Leukocyte Proliferation Autophagosome Organization Negative Regulation Of Mononuclear Cell Proliferation Cytoplasmic Vesicle Positive Regulation Of Telomerase Catalytic Core Complex Assembly Phosphorylation Intracellular Protein Localization Protein Kinase Activity Retrograde Transport, Endosome To Golgi Regulation Of Rho Protein Signal Transduction Positive Regulation Of Small GTPase Mediated Signal Transduction ERBB3:ERBB2 Complex Regulation Of Cellular Component Organization DNA-dependent Protein Kinase Activity Histone H2AXS139 Kinase Activity Cytosolic Transport RNA Polymerase I Core Binding Vacuole Organization Negative Regulation Of Lymphocyte Activation Positive Regulation Of Autophagy Cellular Response To Nitrosative Stress Regulation Of TOR Signaling Peptidyl-serine Autophosphorylation Signal Transduction Kinase Activity Pre-B Cell Allelic Exclusion Cellular Localization AP-type Membrane Coat Adaptor Complex Synaptic Vesicle Coating Cytoplasmic Vesicle Membrane Negative Regulation Of Hyaluronan Biosynthetic Process Clathrin Coat Disassembly Negative Regulation Of Immature T Cell Proliferation In Thymus ErbB-3 Class Receptor Binding Immature T Cell Proliferation In Thymus ERBB2-ERBB4 Signaling Pathway Inositol 1,3,4,5 Tetrakisphosphate Binding Organelle Assembly
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