AP3S1 and SLC30A3

Number of citations of the paper that reports this interaction (PMID 14657250)
29

Data Source:
HPRD (in vitro, in vivo)

		AP3S1	SLC30A3
Gene Name		adaptor-related protein complex 3, sigma 1 subunit	solute carrier family 30 (zinc transporter), member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus AP-type Membrane Coat Adaptor Complex AP-3 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane	Cytoplasm Endosome Late Endosome Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Cell Junction Synaptic Vesicle Membrane Neuron Projection
	Molecular Function	Transporter Activity Protein Binding Protein Transporter Activity	Zinc Transporting ATPase Activity
	Biological Process	Intracellular Protein Transport Anterograde Axon Cargo Transport Insulin Receptor Signaling Pathway Anterograde Synaptic Vesicle Transport	Transport Positive Regulation Of Transport Transmembrane Transport Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Metal ion SLC transporters Zinc efflux and compartmentalization by the SLC30 family Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Zinc transporters SLC-mediated transmembrane transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3	4 interactors: AP3B1 AP3D1 AP3S1 NAALADL2
Entrez ID		1176	7781
HPRD ID		03298	11924
Ensembl ID			ENSG00000115194
Uniprot IDs		Q92572	F5H3B7 Q99726
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Anterograde Axon Cargo Transport Axon Cargo Transport Regulation Of Sequestering Of Zinc Ion Protein Localization Synaptic Vesicle Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Vesicle Localization Intracellular Protein Transport Microtubule-based Movement Establishment Of Organelle Localization Organelle Localization Cellular Localization Protein Localization To Organelle Vesicle-mediated Transport Transport Synaptic Transmission Intracellular Transport Synaptic Vesicle Membrane Organization Regulation Of Ion Homeostasis Microtubule-based Process Eye Pigment Biosynthetic Process Establishment Of Localization In Cell Cell-cell Signaling Positive Regulation Of NK T Cell Differentiation Eye Pigmentation Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Endosome To Melanosome Transport Pigment Granule Maturation Cellular Pigment Accumulation Positive Regulation Of Fatty Acid Beta-oxidation Protein Targeting To Lysosome Positive Regulation Of Glycogen Biosynthetic Process Protein Localization To Lysosome Positive Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Glucose Import In Response To Insulin Stimulus Melanosome Organization Protein Targeting To Vacuole JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Pigment Granule Organization Phosphatidylinositol 3-kinase Signaling Movement Of Cell Or Subcellular Component	Anterograde Synaptic Vesicle Transport Anterograde Axon Cargo Transport Axon Cargo Transport Synaptic Vesicle Transport Positive Regulation Of NK T Cell Differentiation Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Vesicle Localization Vesicle Localization Melanosome Organization Microtubule-based Movement Pigment Granule Organization Establishment Of Organelle Localization Organelle Localization Positive Regulation Of Alpha-beta T Cell Differentiation Synaptic Transmission Cellular Pigmentation Microtubule-based Process Positive Regulation Of T Cell Differentiation Positive Regulation Of Lymphocyte Differentiation Cell-cell Signaling Intracellular Protein Transport Pigmentation Regulation Of T Cell Differentiation Regulation Of Lymphocyte Differentiation Cellular Protein Localization Protein Transport Vesicle Organization Positive Regulation Of T Cell Activation Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Positive Regulation Of Homotypic Cell-cell Adhesion Establishment Of Protein Localization Movement Of Cell Or Subcellular Component Intracellular Transport Positive Regulation Of Cell-cell Adhesion Antigen Processing And Presentation Regulation Of T Cell Activation Eye Pigment Biosynthetic Process Positive Regulation Of Cell Activation Protein Localization Establishment Of Localization In Cell Regulation Of Sequestering Of Zinc Ion Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Eye Pigmentation Regulation Of Lymphocyte Activation Endosome To Melanosome Transport Pigment Granule Maturation
Tagcloud ?			absorption atomic carrier carriers cc concerning flame furnace graphite homozygotes kd micronutrient micronutrients modes mug polymorphisms rs11126936 rs561104 rs5854 rs5859 rs73924411 selenium selenoprotein sep15 solute spectrophotometry trace ultimately zinc
Tagcloud (Difference) ?			absorption atomic carrier carriers cc concerning flame furnace graphite homozygotes kd micronutrient micronutrients modes mug polymorphisms rs11126936 rs561104 rs5854 rs5859 rs73924411 selenium selenoprotein sep15 solute spectrophotometry trace ultimately zinc
Tagcloud (Intersection) ?